Antibodies in Diagnosis and Therapy: Technologies Mechanisms and Clinical Data (Studies in Medicinal Chemistry Series)

Book Description

Monoclonal antibodies have had their impact on biomedical research for more than a decade. Besides their exuberant use as reagents, quite a number of diagnostic and therapeutic approaches have been followed, and an impressive number of technological improvements, e.g., humanization, recombinant miniantibodies, have been elaborated to strengthen the principle. With respect to clinical applications, the first generation of antibody "drugs" is yielding promising results while second and third generation antibody constructs are already underway. This book reviews the status of technological development and brings this into the perspective of clinical results. A rapidly growing amount of clinical data is collected in an expanding number of indications. Hence, the review of clinical study results has been grouped according to the fields of oncology and of chronic and acute inflammation.

Book Description

Constructs a theoretical framework for the study of linear relations and provides underlying concepts, rules, formulae, theorems and techniques. The book compares the inversion, adjoints, completion and closure of various classes of linear operators. It highlights compact and precompact relations.

Customer Reviews:

Texas Tall Tale.......2007-03-12

Robert Franklin Bunting grew up in southwestern Pennsylvania and graduated from Washington College, Princeton Seminary and Princeton College before settling in Texas in 1852 as a Presbyterian minister. He became as ardent a racist, pro-southerner, pro-Confederacy supporter as the air of Texas could make him. In the fall of 1861 Bunting became the chaplain of the 8th Texas Cavalry, Terry's Texas Rangers, and followed that famous regiment until the end of the war. Bunting believed in a personal God who directly intervened in daily life and truly believed that God cared about the fortunes his His chosen people, in this case, the white people of the southern Confederacy. His letters home for publication have been gathered by Thomas W. Cutrer and they are well worth reading. Not only do they contain detailed information about the operations of the Texas Rangers in the Army of Tennessee, but also lengthy sermons on just how God supports the destiny of the Confederacy. Bunting interpolates each southern defeat into a silver lining; in fact, in his last letter, written on April 7, 1865, he know of the evacuation of Richmond and Petersburg, Sherman's advances in North Carolina and Jefferson Davis' flight to Danville, Virginia. Bunting says: if only Davis can escape, raise a new army, smite the dreaded abolitionists, ALL WILL BE WELL. He gets points for keeping a positive attitude. I really wonder whether these letters, which appeared in Texas newspapers, really reflect Bunting's own opinions, or whether they were meant to raise civilian courage. I suspect they really reflect Bunting's actual point of view.

Thomas W. Cutrer is an awful editor. I wonder just how much of Bunting's world view he believes. Bunting is full of brag and blast and Cutrer's editorial comments do not mitigate what Bunting claims, but really add to them. For example, Cutrer quotes a veteran Texas Ranger who claimed in the "Confederate Veteran" that the former commander of the 4th United States Cavalry admitted that the Texans killed 700 of his men throughout the Civil War (page xxii). Cutrer uses this citation twice (including in again in Wheeler's Raid after the Battle of Chickamauga). BUT, Fox's "Regimental Losses" list the 4th US Cavalry's entire Civil War casualties as 3 officers and 59 enlisted men killed or died of wounds and 109 men died of non-hostile causes. Perhaps Cutrer would have us believe the Texas Rangers killed all the 62 Yankees and then perhaps secretly poisoned the 109, and did this four times over to make a total 700 dead Yanks. Similarly, in a December 1861 skirmish with the German 32nd Indiana Infantry, Colonel Terry and 3 privates were killed and a dozen men wounded. Bunting claims that the Texas Rangers killed 114 Hoosiers and nowhere does Cutrer attempt to state the truth. (The 32nd's losses were 10 killed and two dozen wounded.) Perhaps Cutrer does this because he is a bad researcher and cannot ferret out the facts on Federal soldiers, or because he is biased and lets his world view get in the way of writing history. In either case, his editorial comments are very suspect and are the weakest part of this otherwise fine and valuable book.

Average customer rating:

Pretty Good

Soldier Life (Voices of the Civil War)

Manufacturer: Time-Life Books
ProductGroup: Book
Binding: Hardcover

General | Biographies & Memoirs | Subjects | Books

General | Americas | History | Subjects | Books

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ASIN: 078354703X

Customer Reviews:

Pretty Good.......2002-01-08

This book is your standard civil war book, with individual accounts and plenty of facts. This book would do good as a standard book for anyone doing a civil war report or the like.

Slavery in the Clover Bottoms: John McCline's Narrative of His Life During Slavery and the Civil War (Voices of the Civil War Series,)

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Slavery in the Clover Bottoms: John McCline's Narrative of His Life During Slavery and the Civil War (Voices of the Civil War Series,)
John McCline
Manufacturer: University of Tennessee Press
ProductGroup: Book
Binding: Hardcover

African-American & Black | Ethnic & National | Biographies & Memoirs | Subjects | Books

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Book Description

Drawing on the ancient and often-forgotten sources of esoteric Christianity, Valentin Tomberg reflects on the mysteries of humanity's covenant with God in history. The power of these meditations is that they reflect the author's personal spiritual journey into the depths of God's kingdom within-within the soul, within personal relationships, within nature and the cosmos. Part one of Lazarus, Come Forth!-"The Miracle of Raising Lazarus in World History"-looks at an encounter with the Father through the miracles of Creation and the Fall and through Moses and the Old Testament Covenant and the Ten Commandments. Part two, "The Ten Commandments: The Revelation on Mt. Sinai," is a meditation on the seven miracles of Christ as described in the Gospel of St. John, culminating in the raising of Lazarus, the miracle of being raised from forgetfulness, sleep, and death to remembrance, wakefulness, and resurrection. Lazarus thus becomes a paradigm for understanding the spiritual and cultural history of humanity. In part three, "Thy Kingdom Come: The Three Kingdoms of Nature, Humanity, and God," we consider the encounter with the Holy Spirit and living out the life of Christ through the Church. We are asked to reflect on the three kingdoms of God, humankind, and nature, which give natural order and meaning to the Christian life. The union of love and prayer in the Spirit is the focus of the first section of part four, "The Breath of Life," in which we are invited to see our natural breathing as breathing the breath of God. And part four ends with "Natural and Supernatural Images of the Holy Trinity," which discusses the message of the starry heaven at night, the message of the setting Sun, and the message of the birth of a new day. This volume should not be missed by anyone with a serious interest in esoteric Christianity or who merely wishes to go more deeply into the meaning of the Holy Scriptures. A previous edition of this work was titled Covenant of the Heart. It is a translation of Lazarus, komm heraus. The current edition has been revised.

Raising Lazarus: Integral Healing in Orthodox Christianity

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Raising Lazarus: Integral Healing in Orthodox Christianity

Manufacturer: Holy Cross Orthodox Press
ProductGroup: Book
Binding: Paperback

Orthodoxy | Christianity | Religion & Spirituality | Subjects | Books

General | Religion & Spirituality | Subjects | Books
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ASIN: 1885652798
Release Date: 2005-03-30

Product Description

I believe that Raising Lazarus will do much to establish pastoral counseling as a vital integrative ministry within the modern Orthodox Christian Church and off er valuable perspective to those in other denominations as well. Surely the authors have responded successfully to Archbishop Demetrios' challenge to "off er Orthodox Christianity to contemporary America." Their reward will be that they will help many persons in their eff orts to achieve spiritual growth and healing. We are all grateful. Dimitrios G. Oreopoulos Raising Lazarus takes an adventuresome approach to the fundamental practical issue raised by the Christian faith: How are we to live the union of divine and human life that is off ered to us by Christ? The book's clear reply is: Certainly not by a 'spiritual' manner of living, if that means ignoring the psychological and bodily aspects of our being. In their diff erent ways the contributors invite us to use the insights of the Fathers as well as those of contemporary depth psychology in our search for wholeness in Christ, thereby confi rming that the Tradition of the Church is quite capable of facing the challenges of the new century in a lively and constructive manner. Bishop Basil of Sergievo

Average customer rating:

Poignant, Unpretentious, and Moving
"Raising Lazarus"
Very informative! Hard to put down!

Raising Lazarus: A Memoir
Robert Jon Pensack , and Dwight Arnan Williams
Manufacturer: Backinprint.com
ProductGroup: Book
Binding: Paperback

General | Biographies & Memoirs | Subjects | Books

Medical | Professionals & Academics | Biographies & Memoirs | Subjects | Books

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ASIN: 0595349528

Book Description

Raising Lazarus is Dr. Robert Pensack's personal memoir of his battle to maintain his sanity in the face of extraordinary suffering.

Dr. Pensack's story chronicles his near life-long struggle with a mortal illness, Hypertrophic Cardiomyopathy, or HCM (formally known as IHSS), a genetic illness marked by abnormality of the heart muscle. After the disease claimed the life of his young mother, the adolescent Pensack—and his brother Richard, who also suffered from HCM—went on to become chronic-research heart patients at The National Institutes of Health in Bethesda, Maryland. They endured a litany of surgeries and multiple near-death experiences caused by cardiac arrests until, thirty years later, both received heart transplants that saved their lives. Remarkably—and coincidentally—Dr. Pensack played a vital role in the evolution of organ transplantation and in his own survival, helping to produce one of the anti-rejection drugs with which he himself was later treated at the time of his greatest need.

From recounting his feeling of being condemned to an existence laden with insufferable burden to the hope restored through the ultimate gift of life, Raising Lazarus is Dr. Pensack's inspirational story of survival and triumph.

“Extraordinary…A doctor's memoir of his struggle against his own illness…An intimate account of the remarkable medical advances of the last few decades from [a] unique point of view.”—New York Times Book Review

Customer Reviews:

Poignant, Unpretentious, and Moving.......2000-08-24

I stumbled across this book in a used book store and read it because I had nothing else on hand. It gripped me from the first page, where the author describes his four year old son, Max, staring down at the author on the floor as he suffers a heart attack. Before this book, I knew little about heart diseaseof any sort. I've learned a lot about heart disease, but also about courage and determination. This book will appeal to a broad range of readers. It is beautifully written, often amusing, and always gripping. I barely survived his heart transplant, and have a new awe for anybody who contemplates undergoing this procedure.

"Raising Lazarus".......2000-05-05

Being an HCM victim myself, I found this book highly informative, educational, moving, emotional, and inspiring. I could relate to his suffering, his motivation, and his tenacity. It's a miracle that he survived to share his experiences. This book gave me the determination to educate myself, and motivate myself to live with and survive this condition, Hypertrophic Cardiomyopathy. A great read for everyone; highly recommend!

Very informative! Hard to put down!.......1998-05-31

Having a 8 year old son with IHSS/HCM I found this book the most informative of the hundreds of articles I have read. This book gives the details patients,(or in this case parents of the patient)want to know. I have read it three times and will read it again. I like the in depth discussions about being a heart patient,both the physical and emotional affects.

Warriors Don't Cry/Nixon: A Life/Esther: Her Murder Haunts a Small Town in Oklahoma/Raising Lazarus: A Memoir (Reader's Digest Today's Best Nonfiction, Volume 32: 1995)

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Warriors Don't Cry/Nixon: A Life/Esther: Her Murder Haunts a Small Town in Oklahoma/Raising Lazarus: A Memoir (Reader's Digest Today's Best Nonfiction, Volume 32: 1995)
Melba Patillo Beals , Jonathan Aitken , Leonard Sanders , and MD Robert Pensack
Manufacturer: Reader's Digest Association
ProductGroup: Book
Binding: Hardcover
ASIN: B000GP1WJM

After the Raising of Lazarus (Cork 2005 Translation Series)

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After the Raising of Lazarus (Cork 2005 Translation Series)
Ileana Malancioiu
Manufacturer: Southword Editions
ProductGroup: Book
Binding: Paperback

General | Poetry | Literature & Fiction | Subjects | Books

Auferstehung und Leben: Joh 11,1-12,19 als Spiegel johanneischer Redaktions- und Theologiegeschichte (Biblische Untersuchungen)

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Auferstehung und Leben: Joh 11,1-12,19 als Spiegel johanneischer Redaktions- und Theologiegeschichte (Biblische Untersuchungen)
Josef Wagner
Manufacturer: Pustet
ProductGroup: Book
Binding: Perfect Paperback

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ASIN: 3791711733

Female Mourning And Tragedy in Medieval And Renaissance English Drama: From the Raising of Lazarus to King Lear (Studies in Performance and Early Modern ... in Performance and Early Modern Drama)

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Female Mourning And Tragedy in Medieval And Renaissance English Drama: From the Raising of Lazarus to King Lear (Studies in Performance and Early Modern ... in Performance and Early Modern Drama)
Katharine Goodland
Manufacturer: Ashgate Publishing
ProductGroup: Book
Binding: Hardcover

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ASIN: 0754651010

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Lazarus of Bethany
J. W Haggard
Manufacturer: distributed by Cedar Fort, Inc
ProductGroup: Book
Binding: Unknown Binding

Lazarus: A Contemporary Reading of John 11:1-46 (Zacchaeus Studies. New Testament)

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Lazarus: A Contemporary Reading of John 11:1-46 (Zacchaeus Studies. New Testament)
Brendan Byrne
Manufacturer: Liturgical Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0814656579

Marta y Maria (Historias de la Biblia para ninos)

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Marta y Maria (Historias de la Biblia para ninos)
Jaime Serrano
Manufacturer: Publications International
ProductGroup: Book
Binding: Unknown Binding

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