Combinatorial Chemistry: A Practical Approach (Practical Approach Series)

Book Description

Combinatorial Chemistry is a genuine practical guide covering all the major areas of combinatorial chemistry from an experimental and conceptual point of view. Being one of the most powerful of modern technologies, combinatorial chemistry has had implications to many areas of chemistry and biology and the current approaches to drug, catalyst, receptor, and materials development and discovery are all included in this volume. It also contains protocols on solid, liquid, and solution phase synthesis and expedient methods of library screening and evaluation. The use of automation and robotics is also explained. It is written at a level easily accessible to novices and will enable readers to use combinatorial techniques to the best advantage.

Combinatorial Chemistry: A Practical Approach (Methods and Principles in Medicinal Chemistry)

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Combinatorial Chemistry: A Practical Approach (Methods and Principles in Medicinal Chemistry)

Manufacturer: Wiley-VCH
ProductGroup: Book
Binding: Hardcover

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Book Description

As we enter the new millennium, combinatorial chemistry is providing significant impetus to new innovations in synthetic chemistry. Combinatorial chemistry has rapidly become the rising star among research methods, allowing scientists to efficiently test the feasibility of a multitude of new compounds.

The pursuit of new drugs is but one challenging field in which these combinatorial methods are particularly advantageous, helping researchers meet the modern-day demands of a highly competitive environment.

This book emphasises that modern combinatorial synthesis is possible not only in the solid phase, but also in solutions. Moreover, it discusses computer-assisted methods as well as the apparatus and instrumentation required for the combinatorial method. Successful and experienced researchers in the leading pharmaceutical companies and most renowned research institutes offer a solid insight and perspective into this diverse field.

A 'must' for every scientist in the area of pharmaceutical research.

Book Description

One of the great works of American exploration literature, this account of a scientific expedition forced to survive famine, attacks, mutiny, and some of the most dangerous rapids known to man remains as fresh and exciting today as it was in 1874.

Customer Reviews:

Bold Explorer.......2007-07-14

I got this book to read while I was rafting the Grand Canyon. It was well worth it. John Wesley Powell's description of his unbelivable expedition helped me put into words the spectacular scenes that makes up the Grand Canyon. I recommend this book to anyone who is considering traveling down the Colorado River.

Perilous journey into a sublime landscape.......2006-04-25

Anyone who is enthralled by the beauty of the Southwest, or as Powell defines it - the Colorado River watershed, should read this book. It's not the same now as it was in his day. For one thing, Glen Canyon, which he named, is now submerged under Lake Powell (could any name be more ironic?). No one today can feel the same kind of wonder and awe as Powell and his companions did as they pushed their boats into the raging rapids of the muddy Colorado without having any idea of what was ahead. Even the part of the Colorado watershed that has not been developed, and there is a considerable extent of land under protective status, today has nothing like the remoteness that Powell experienced. Everything has been mapped and carefully scutinized.

Yet, anyone who has spent some time sizing up the immense water-carved rock canyons, can still feel something of the sublimity that Powell felt. It requires more imagination; it is true, but anyone who is determined to make more of a commitment than just standing at the rim of the Grand Canyon can still experience the really sublime features of this landscape. How much more difficult will it be in the future? Will these wilderness wonders become more degraded?

The book describes by daily journal entries the historic river run of 1868 starting at the Flaming Gorge in Wyoming and ending at the Virgin River as well as a follow-up expedition the next year. Powell does not overdo the apprehensions and hardships of himself and companions, nor does he make mention that he accomplished the physical exertion of climbing the canyon walls and navigating the boats with one arm: but largely confines himself to descriptions of the events and the incredible landforms. The extent of the journey and all the spectacular features that he finds and names is impressive. That Powell's group experienced hardships there can be no doubt.

One of the more interesting parts of the book to me was the way Powell approached the Indian tribe that killed his three companions, who decided to abandon the expedition and hike out of the Canyon. In those frontier days, it was the accepted norm to meet violence with violence. But Powell, I thought here, really showed himself to be an exceptional human being. He had a inquiring mind and a sincere desire to learn everything he could without inflicting retribution.

It is shameful that students today don't know this man!.......2006-01-09

I find it totally unexcuseable that today's young college students (especially earth and environmental science types) do not know this man; yet, they all know Edward Abbey. Powell was not a scientist by today's standards but yet he managed to do many great things. He stood in opposition to the popular belief at that time that the West was a virgin Utopian land awaiting industrial and population exploitation from eastern society. He saw a great empty space in the National maps of the West and set about to explore and understand and map this area. He was a geologist, ecologist, ethnologist, and anthropologist all wrapped up in a persona that was at one time a soldier and commander. His exploration of the Grand Canyon and the Colorado River is a terrific read for anyone looking for an adventure read. Its a scientific quest turned whitewater adventure. Abbey, on the other hand, has never done anything as substantial as what Powell did for our basic knowledge and appreciation of the West. Furthermore, Powell's vision isn't clouded by the selfish, militant, eco-geek goggles through which Abbey viewed the West.

A classic, I guess.......2005-09-30

John Wesley Powell was a fascinating guy.
John Wesley Powell was a scientist, geologist, and Civil War veteran whose right arm was shot off by a cannonball; he was the man who named Glen Canyon, and the man Lake Powell was named for. He was the first man to lead an expedition down the Colorado--the first two expeditions, actually--back when the river flowed wild, without dams.
He didn't worry about all the details like a knowledgeable crew, funds, both arms, having an experienced crew, not knowing if there was a Niagara-sized waterfall around the next bend or not, and so on--he just went. He understood you don't need experience to gain experience. He and his crew paid for their inexperience by nearly drowning, nearly starving, and by misadventure after misadventure but in the end MOST of their group emerged from the southern end of the Grand Canyon with stories, experiences, and first-hand knowledge of a part of the world that few people had ever seen before.
(Three of his crew abandoned the expedition, and their fates are uncertain.)
This is Powell's story. It's also a story of the geology of the Colorado Plateau, of the Colorado River, and of the West. It's not a perfect account, but it is a classic one. Powell's prose is at times high-falutin', he recklessly combines details from his first and second expedition, and he gives too little credit to his crew, but he is always an optimist, and always fun to read.
Take a river trip, and take this along. Or, take "Down the Great Unknown" by Edward Dolnick--that's a good account of that trip as well. (I actually prefer it.)

A great adventure story .......2005-09-13

This is a classic adventure tale, inspiring in that it's a true story of courage and endurance. John Wesley Powell and his companions (including a wonderful illustrator) set out on the Colorado River to chart what was the last unexplored territory of the U.S., the Grand Canyon. Powell was a Civil War veteran who, despite the loss of one of his arms, took on the mighty untamed Colorado in wooden lorries. He is the person for whom Lake Powell is named and interestingly his story is featured in a short IMAX film about the Grand Canyon. The book had originally been sold to a magazine in serial form and Powell's adventure followed avidly by "folks back East". Reading this book transports you back to a different time when the written word was the primary means of reporting stories like this.

THE EXPLORATION OF THE COLORADO RIVER AND ITS CANYONS.

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THE EXPLORATION OF THE COLORADO RIVER AND ITS CANYONS.

Manufacturer: Dover
ProductGroup: Book
Binding: Paperback
ASIN: B000HG32PW

The romance of the Colorado River: The story of its discovery in 1540, with an account of the later explorations, and with special reference to the voyages ... the great canyons (Classics of the Old West)

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The romance of the Colorado River: The story of its discovery in 1540, with an account of the later explorations, and with special reference to the voyages ... the great canyons (Classics of the Old West)
Frederick Samuel Dellenbaugh
Manufacturer: Time-Life Books
ProductGroup: Book
Binding: Unknown Binding

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ASIN: 0809440024

Book Description

in half an hour a great wave several feet in height, could be distinctly seen flashing and sparkling in the moonlight, extending from one bank to the other and advancing swiftly upon us. While it was only a few hundred yards distant, the ebb tide continued to flow by at the rate of three miles an hour. A point of land and an exposed bar close under our lee broke the wave into several long swells, and as these met the ebb the broad sheet around us boiled up and foamed like the surface of a cauldron, and then, with scarcely a moment of slack water, the whole went whirling by in the opposite direction. In a few moments the low rollers had passed the islands and united again in a single bank of water, which swept up the narrowing channel with the thunder of a cataract.

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The Exploration of the Colorado River and Its Canyons
Major John W. Powell
Manufacturer: Dover
ProductGroup: Book
Binding: Paperback
ASIN: B000NWAI1G

The Exploration of The Colorado River and its Canyons (formerly titled: Canyons of Colorado).

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The Exploration of The Colorado River and its Canyons (formerly titled: Canyons of Colorado).
J. W. POWELL
Manufacturer: Dover
ProductGroup: Book
Binding: Paperback
ASIN: B000OFZDDK

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The Romance of the Colorado River - The Story of Its Discovery in 1540, with an Account of the Later Explorations, and with Special Reference to the Voyage of Powell Through the Line of the Great Canyons

Manufacturer: G. P. Putnam's Sons
ProductGroup: Book
Binding: Hardcover
ASIN: B000EERX5W

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The Romance of the Colorado River. The Story of its Discovery in 1540, with an Account of the Later Explorations, and with Special Reference to the Voyages of Powell through the Line of the Great Canyons.
Frederick S. DELLENBAUGH
Manufacturer: Time-Life facsimile reprint, 1982 (1902).
ProductGroup: Book
Binding: Hardcover
ASIN: B000JW0N7E

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The Exploration of the Colorado River and Its Canyons
J. W. Powell
Manufacturer: Dover Publications Inc.
ProductGroup: Book
Binding: Paperback
ASIN: B000NX0ZIG

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The Exploration of the Colorado River and Its Canyons
John Wesley Powell
Manufacturer: Penguin (Non-Classics)
ProductGroup: Book
Binding: Paperback
ASIN: B000OJ4AMQ

The Exploration of the Colorado River and Its Canyons (Penguin Classics)

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The Exploration of the Colorado River and Its Canyons (Penguin Classics)
John Wesley Powell Wallace Stegner
Manufacturer: Penguin Classics
ProductGroup: Book
Binding: Paperback
ASIN: B000OJ37SO

Customer Reviews:

Excellent as a textbook.......2006-11-22

I use this book in teaching a Bankruptcy class to California paralegal students. It is an excellent introduction to the bankruptcy system, and includes discussions of both consumer and business bankruptcies (with a definite emphasis on the consumer side). I expecially appreciate the thorough treatment of the BAPA (laws that changed in October 2005).

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Basic Bankrupt Law for Paralegals
David L. Buchinder
Manufacturer: Panel Pub
ProductGroup: Book
Binding: Paperback

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Basic Bankruptcy Law for Paralegals: Forms Manual

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Need to locate David L. Buchbinder

Basic Bankruptcy Law for Paralegals: Forms Manual
David L. Buchbinder
Manufacturer: Aspen Publishers
ProductGroup: Book
Binding: Paperback

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Customer Reviews:

Need to locate David L. Buchbinder.......2000-10-04

Dear David: I hope somehow you get this. I was a client of yours in 1992-3 with my company RNH Enterprises, Inc. I need to ask you a question or two. Hoping to hear from you. Richard

21st Century Complete Guide to Bankruptcy: Comprehensive Coverage of Federal Bankruptcy Courts and Bankruptcy Basics, the Bankruptcy Code and New Bankruptcy ... and Trustee Information (Two CD-ROM Set)

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21st Century Complete Guide to Bankruptcy: Comprehensive Coverage of Federal Bankruptcy Courts and Bankruptcy Basics, the Bankruptcy Code and New Bankruptcy ... and Trustee Information (Two CD-ROM Set)
U.S. Government
Manufacturer: Progressive Management
ProductGroup: Book
Binding: CD-ROM
ASIN: 1592482597

Book Description

This comprehensive set of two CD-ROMs provides a complete guide to bankruptcy: United States Bankruptcy Courts; U.S. Bankruptcy Court Publications, Forms, and Statistics; Bankruptcy Basics; Bankruptcy Case Opinions; United States Trustee Program; Bankruptcy Trustees; Bankruptcy Code; Bankruptcy Reform Act; Bankruptcy-Related Legislation and Activities of the 108th Congress; Chapter 7, 9, 11, 12 and 13 Bankruptcies; District Bankruptcy Courts; and Financial Privacy in Bankruptcy.

The Bankruptcy Courts-have exclusive jurisdiction over bankruptcy cases. Each of the 94 federal judicial districts handles bankruptcy matters. The primary purposes of the law of bankruptcy are: (1) to give an honest debtor a "fresh start" in life by relieving the debtor of most debts, and (2) to repay creditors in an orderly manner to the extent that the debtor has property available for payment. U.S. Bankruptcy Courts coverage includes: About the Courts; Library; Frequently Asked Questions; Fees; Basics; Official Forms; Statistical Reports; Publications; Opinions. Extensive District Court coverage includes Local District Rules, Forms and Publications; Statistics; Judges' Decisions; Judges' Procedures; Information Manuals. U. S. Trustee Program oversees the administration of bankruptcy cases and private trustees. Coverage includes: Mission Statement; Outreach; Organization and Information; Regions; Private Trustee Listings & Library; Vacancies; Rules, Decisions, Guidelines & Policy; Debtor Identification Pilot Program Report; Financial Privacy in Bankruptcy: A Case Study on Privacy in Public and Judicial Records; Articles; Cases; Statistics; Testimony; 2001 Annual Report; Trustee Region coverage for all twenty-one (21) Regions. Bankruptcy-Related Legislation and Activities of the 108th Congress coverage includes: Involuntary Bankruptcy Improvement Act of 2003; Bankruptcy Abuse Prevention and Consumer Protection Act of 2003.

In all, the disc set has over 74,000 pages reproduced using Adobe Acrobat PDF software - allowing direct viewing on Windows and Apple Macintosh systems. Reader software is included on the CD. There is no other reference that is as fast, convenient, comprehensive, and portable.

Our CD-ROMs are privately-compiled collections of official public domain U.S. government files and documents - they are not produced by the federal government. They are designed to provide a convenient user-friendly reference work, utilizing the benefits of the Acrobat format to uniformly present thousands of pages that can be rapidly reviewed or printed without untold hours of tedious searching and downloading. Vast archives of important public domain government information that might otherwise remain inaccessible are available for instant review no matter where you are. This book-on-a-disc set makes a great reference work and educational tool.

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Bankruptcy Basics
Leonidas Ralph Meacham
Manufacturer: Diane Pub Co
ProductGroup: Book
Binding: Paperback

Bankruptcy | Business | Law | Subjects | Books
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ASIN: 0788185438

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Bankruptcy Basics (028-004-00106-7)

Manufacturer: US Government Printing Office
ProductGroup: Book
Binding: Mass Market Paperback
ASIN: 0160592429

Book Description

Provides basic information to debtors, creditors, court personnel, the media, and the general public on different aspects of the federal bankruptcy laws. Designed to provide individuals who may be considering bankruptcy with a basic explanation of the different chapters under which a bankruptcy case may be filed. Answers some of the most commonly asked questions about the bankruptcy process.

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The basics of bankruptcy
William R Mapother
Manufacturer: Creditors Law Center
ProductGroup: Book
Binding: Unknown Binding

Bankruptcy | Business | Law | Subjects | Books
ASIN: B00071OUYE

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Im: Basic Bankruptcy Law Paral 5e

Manufacturer: Aspen Publishers
ProductGroup: Book
Binding: Paperback

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The New Bankruptcy Act And The Basics Of Bankruptcy, Default, Workout, Repossession And Foreclosure: A Secured Lender's Perspective

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The New Bankruptcy Act And The Basics Of Bankruptcy, Default, Workout, Repossession And Foreclosure: A Secured Lender's Perspective
Sean C. Kulka , G. Frank Nason IV , and Daniel P. Sinaiko
Manufacturer: Lorman Education Services
ProductGroup: Book
Binding: Spiral-bound
ASIN: B000KU0UIC

Product Description

Readers of this manual will gain extensive knowledge regarding the Bankruptcy Abuse Prevention and Consumer Protection Act of 2005. We will discuss loan workouts and restructuring, as well as specific basics under Georgia law such as real property foreclosure, bankruptcy, personal property repossession, and foreclosures and judgment creditor.

Teacher's manual, Basic bankruptcy law for paralegals

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Teacher's manual, Basic bankruptcy law for paralegals
David L Buchbinder
Manufacturer: Little, Brown and Co
ProductGroup: Book
Binding: Unknown Binding

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ASIN: 0316114529

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