Advances in Amino Acid Mimetics and Peptidomimetics, Volume 1 (Advances in Amino Acid Mimetics and Peptidomimetics)

Book Description

Peptidomimetics are compounds which mimic the biological activity of peptides while offering the advantages of increased bioavailability, biostability, bioefficiency, and bioselectivity against the natural biological target of the parent peptide. Examples of peptidomimetics have been isolated as natural products, synthesized as libraries from novel subunits, and designed on the basis of X-ray crystallographic studies and through an intricate knowledge of the biological mode of action of natural peptides. They offer challenging synthetic targets and are increasingly important medicinal agents and biological probes. As a consequence, peptidomimetics embrace much of what is modern medicinal and organic chemistry. This volume highlights some recent and exciting developments in the area.

Customer Reviews:

A very interesting new molecular approach.......2000-04-25

This book presents a new domain, whose applications might be greatly increased in the coming years. Construction of peptidomimetic molecules it a useful tool for the development of new drugs. The major drawback of peptides as possible drugs is their poor bioavailability and their degradation in the body. Therefore, molecules resembling the tertiary structures of interesting peptides, but having more suitable bioavailability properties might proove very useful as candidate drugs. That is why this discipline is very promising. To date, i haven't found any text books addressing this issue, this book might be the first one. I liked the fact that its contents cover many medical domains. However, I would have liked that the authors have addressed the problem of increasing bacterial resistance, the need to develop new antibacterials, and eventually the possible role of peptidomimetics in that field. Another thing that i would have liked to find in the contents, is a brief review on the phage display technique, its potential of finding useful peptides that might serve for the construction of peptidomimetics.

Book Description

Faulkner examines the changing relationship of black to white and of man to the land, and weaves a complex work that is rich in understanding of the human condition.

Customer Reviews:

City of Man, City of Nature.......2007-02-09

The Southern landscape of field and swamp and woods becomes a prominent character throughout these rich, complex stories. Indeed, I'd imagine most of Go Down, Moses could provocatively serve an environmental history class. 'Pantaloon In Black' is perhaps my favorite here; this haunting tale, full of powerful, archetypal imagery, is mentioned far less often than some of the other, more well-known works, but it struck me immediately. 'The Bear,' with that sprawling coda tackling humankind's relationship with the land, is rather a reading experience unto itself.

Opaque and Exuberant.......2005-06-21

Go Down Moses was my latest stab at Faulkner. I'd certainly recommend, as someone before me has, a college course or reading group study of this book, and just about any other great Faulkner work. That being said, even a marginal understanding of this book (like mine) is worth the time and effort.

Go Down Moses is a collection of temporally fragmented novellas and stories concerning the McCaslin family's past, present, and future legacy in a southern town. Thematically, Faulkner tackles a bevy of issues--race, slavery, paternity, masculinity, the natural and supernatural. The stories are loosely centered around Isaac McCaslin, descendant of Carothers McCaslin--a plantation owner.

The best regarded and most complex story is considered to be "The Bear." Over a hundred pages long, it follows (often meandering) the hunting team that includes young Isaac, ex-Civil War officers, and a half Choctaw/half African hunter (Sam Fathers) as they obsessively pursue the invincible bear Old Ben through the years. Bursting with imagery and symbolism, "The Bear" will please Faulkner fans and hunters alike.

My personal favorites are "Was" and "The Fire and the Hearth." Lucas, half-black and the oldest living McCaslin save Isaac, searches for buried gold on Carothers Edmonds's plantation, where he farms, while his wife, fed up with his mania, gives him an ultimatum. An unlikely and graceful story of marital bonds and family values, and the triumph of humanity and dignity over birthright

Beautifully Written but Fragmented.......2004-12-15

This is in my opinion, not one of Faulkner's best books. It is, however, a beautifully written story of generations of a single exstended family. Because the book is written in that it is made up of several short stories instead of chapters, the story can seem fragmented at times, leaving you wondering what happened to the characters in the last piece. It is difficult at times to keep characters straight, but the best story in the book is by far "The Fire in the Hearth" which follows the Lucas and Molly, this part of the book is often overlooked in the shadow of the long and tedious "The Bear"- but should be read and enjoyed.
Overall the book is a good introduction to Faulkner, but may be a challenging read to some.

Beautiful, and occasionally readable.......2004-06-24

Faulkner's writing is very often beautiful. Maybe even unceasingly beautiful. But for most readers, it will only occasionally be completely readable.

Despite frequently inaccessible language and structure, the text will still likely be worthwhile to pretty much anyone fluent in the language simply because what can be read and can be understood is just that good. But ideally, a review shouldn't have to begin with the word 'despite.'

A style of writing accessible only to the author is literary (...). Joyce does a far better job of earning that description, but Faulkner isn't far behind.

Sometimes, a great writer will come along, who can relate deep meaning through simple, every day language. That's not Faulkner.

You may have to read through some of the passages in Go Down Moses three or four times in order to figure out exactly what's going on. And an absolutely fundamental plot point might be contained within three words of an almost nonsensically drawn-out sentence of otherwise little relevance.

Deriving the full meaning of a Hemingway story will probably take you a third the time deriving half the meaning of a Faulkner story will. Is it worth three times the effort to hear half the story in Faulkner's words? That's up to you.

Good Picture Words, Weak Story Line.......2004-05-26

"Go Down , Moses" was formed out of the melding of a series of short stories into a novel about the McCaslin family of Jefferson, Mississippi. Extending through the life of Ike McCaslin, his youthful experiences help him to later face a crucial test about his family's legacy. The complex racial relations of Faulkner's novels introduce the reader to a world which most of us could never understand or even imagine.

Like other Faulkner novels, I find the dialogue and stream of consciousness to be the most alluring qualities of the book. The thoughts of the characters, the descriptions of the scenes and the dialogues paint mental pictures of the action in which the reader can feel himself to be a part.

Book Description

The years 1942 to 1954 saw Faulkner's greatest success--and greatest inner anguish. Plagued by depression and alcohol, he knew he had more to achieve and a finite amount of time and energy to achieve it. This volume gathers four groundbreaking works from this fascinating period. "Go Down, Moses" is a haunting novel that explores the intertwined lives of black, white, and Indian inhabitants of Yoknapatawpha County. It includes "The Bear," one of the most famous works in American fiction. "Intruder in the Dust," a detective novel, is a compassionate story of a black man on trial and the growing moral awareness of a southern white boy. "Requiem for a Nun" tells the fate of a passionate, haunted Temple Drake and her tortured redemption. "A Fable," Faulkner's recasting of the Christ story set in World War I, earned him the Pulitzer Prize.

New Essays on Go Down, Moses (The American Novel)

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New Essays on Go Down, Moses (The American Novel)

Manufacturer: Cambridge University Press
ProductGroup: Book
Binding: Paperback

General | Essays | Literature & Fiction | Subjects | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books
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ASIN: 0521456096

Book Description

Go Down, Moses (1942) came to fruition during the second world war and was written during one of Faulkner's most traumatic periods, yet it has fallen to critical neglect amid the vast scholarship on the great Southern writer. In part, this collection aims to tilt the balance, forcing the reader beyond critical commonplaces through asking challenging questions. The five essays assembled here explore the tensions of race and gender apparent throughout the novel.

Go Down, Moses!: Daily Devotions Inspired by Old Negro Spirituals

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Negro spiritual devotion book

Go Down, Moses!: Daily Devotions Inspired by Old Negro Spirituals

Manufacturer: Judson Press
ProductGroup: Book
Binding: Paperback

General | Religion & Spirituality | Subjects | Books

Devotionals | Spirituality | Religion & Spirituality | Subjects | Books
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ASIN: 0817013725

Book Description

African American spirituals are the heart of all other American music and comprise the taproot of the musical expression of the black religious experience. "Go Down, Moses!" offers 365 daily devotions and includes a suggested Scripture reading for each day as well as a short prayer.

Tying into the inspiration generated by African American spirituals, each devotion highlights the Negro spirituals that for decades have helped define African American religious culture. The suggested Scripture readings take readers through the first five books of the Old Testament, plus Joshua, and the first four books of the New Testament, plus Acts and Revelation. Readers are guided through a reading of the Bible during the course of one year.

Customer Reviews:

Negro spiritual devotion book.......2007-04-01

The book has the words to many negro spirituals so from that angle it is helpful. I however find that the devotional aspect is too short. For the most part the devotional aspect is about 4 lines. I was looking for a full page devotion.

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Go Down Moses: Notes (Cliffs Notes)
William Faulkner
Manufacturer: Cliffs Notes
ProductGroup: Book
Binding: Paperback

General | Education | Nonfiction | Subjects | Books

Book Notes | Education | Reference | Subjects | Books

Literary Criticism & Collections | Literature | Children's Books | Subjects | Books
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ASIN: 0822005379

Book Description

As Faulkner matured, his vision was colored by optimism, where the world was capable of decent and worthwhile values. This collection presents stories of difficulty for both white and black people, yet the tone is one of compassion, not despair.

Go Down, Moses: The Story of Harriet Tubman

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Go Down, Moses: The Story of Harriet Tubman
Arline Chase
Manufacturer: Write Words, Inc.
ProductGroup: Book
Binding: Paperback

Contemporary | General | Literature & Fiction | Subjects | Books
ASIN: 1594310130
Release Date: 2004-05-04

Book Description

Through her wits, intelligence, determination, and bravery, she not only changed the course of her own life, but that of her family and countless other African-Americans.

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The Modern Library
William Faulkner
Manufacturer: The Modern Library
ProductGroup: Book
Binding: Hardcover

Threads Cable-Strong: William Faulkner's Go Down, Moses

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Bound by strong cables

Threads Cable-Strong: William Faulkner's Go Down, Moses
Dirk, Jr. Kuyk
Manufacturer: Bucknell Univ Pr
ProductGroup: Book
Binding: Hardcover

British | Short Stories | Literature & Fiction | Subjects | Books
ASIN: 0838750370

Customer Reviews:

Bound by strong cables.......2001-01-05

While I may be biased, since the author is a former professor and good friend, "Threads Cable Strong" presents a compelling argument that "Go Down, Moses" stands by itself as a complete novel rather then a collection of short stories. With particular attention to the sections of "The Bear" that make little sense lacking the context of the greater novel, this book is convincing, interesting, and well written.

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The Making of Go Down, Moses
James Early
Manufacturer: Southern Methodist Univ Pr
ProductGroup: Book
Binding: Hardcover

Book Description

When you're trying to obtain relief from debt, the last thing you need is to pay costly legal fees for bankruptcy proceedings. With this kit's detailed, easy-to-follow instructions and up-to-date forms, you can: prepare and file your own Chapter 7 Bankruptcy, Chapter 11 Reorganization or Chapter 13 Wage Earner Plan

eliminate most debts equitably adjust most secure obligations possibly stop foreclosures, repossessions and wage garnishment

28 FORMS INCLUDED: Bankruptcy Information Checklist Certification and Signature of Non-Attorney Bankruptcy Petition Preparer Voluntary Bankruptcy Petition Exhibit A to Voluntary Petition (for a business filing Chapter 11) Exhibit C to Voluntary Petition (identifies property that may pose threat to public safety) Application to Pay Filing Fees in Installments Order Approving Payment of Filing Fees in Installments List of Creditors Holding 20 Largest Unsecured Claims Summary of Schedules Schedules: A-J Declaration Concerning Debtor's Schedules Statement of Financial Affairs Chapter 7 Individual Debtor's Statement of Intention Notice of Chapter 7 Bankruptcy Case, Meeting of Creditors and Deadlines Notice of Chapter 11 Bankruptcy Case, Meeting of Creditors and Deadlines Notice of Chapter 13 Bankruptcy Case, Meeting of Creditors and Deadlines Discharge of Debtor Proof of Claim Statement of Social Security Number

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