Pharmaceutical Formulation Development of Peptides and Proteins (The Taylor & Francis Series in Pharmaceutical Sciences)

Book Description

Pharmaceutical formulation of peptides and proteins has become an important part of modern drug development. Many new drugs are based on peptide or protein recombinant technology going hand in hand with more traditional pharmaceutical formulation. In order to develop products with optimal characters, it is important to give scientists interdisciplinary knowledge and a thorough understanding of the complex nature of pharmaceutical formulation of peptides and proteins. This comprehensive volume brings the different aspects of peptide and protein formulation into focus, beginning with the fundamentals of the production of peptides and proteins, ranging from peptide synthesis and recombinant DNA technology to protein purification. It discusses the characterization and chemical stability of peptides and proteins, before moving on to formulation, detailing peptides and proteins in solution and as suspensions, as well as lyophilized peptide and protein products. There follows a case study on drug delivery systems for alternative routes of administration. Finally, regulatory aspects are discussed in terms of chemical and pharmaceutical documentation. Each chapter is written by experts in their respective areas. Scientists in the industry and academia, and postgraduate students in pharmaceutical science will find this a valuable resource, which can be dipped in to as a reference, or studied as a whole.

Basic Protein and Peptide Protocols (Methods in Molecular Biology)

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Basic Protein and Peptide Protocols (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Paperback

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ASIN: 0896032698

Book Description

Basic Protein and Peptide Protocols offers an excellent collection of reproducible, step-by-step laboratory methods covering three major areas: (1) the quantitation and characterization of proteins, (2) the electrophoretic and blotting procedures used in protein isolation and characterization, and (3) the analysis of protein and peptide structure. THOUSANDS of labs are already using Basic Protein and Peptide Protocols-you should be too!

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Peptides: Chemistry and Biology
Norbert Sewald , and Hans-Dieter Jakubke
Manufacturer: Wiley-VCH
ProductGroup: Book
Binding: Hardcover

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ASIN: 3527304053

Book Description

Peptides play a decisive role in many physiological processes, whether as neurotransmitters, hormones or antibiotics. The rapid developments in peptide research over the past few decades make it almost impossible for newcomers to gain an overview. This means an easily comprehensible yet concise introduction is vital.

This unique work covers all the important aspects of this wide-ranging field in one handy volume. On the basis of the fundamental chemical and structural properties of peptides, this reference runs the gamut from analysis, the occurrence and biological importance of peptides, via chemical, biochemical and genetic methods of peptide synthesis, right up to peptide libraries, peptide design and their role in drug research. Yet this book offers much more than a mere overview of the latest level of research. An encyclopedic appendix with valuable data on more than 500 biological relevant peptides and proteins, a comprehensive register and details of further literature references make this the ideal reference for all questions regarding peptide research. For newcomers and specialists alike.

Protein and Peptide Analysis by Mass Spectrometry (Methods in Molecular Biology)

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A good hand-book on protein analysis by MS

Protein and Peptide Analysis by Mass Spectrometry (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0896033457

Book Description

Leading practitioners authoritatively describe the newest and most effective spectrometric techniques for the analysis of proteins and peptides. The areas covered range from the elucidation of primary and secondary protein structure and the rapid identification of proteins using database techniques to methods for sequencing, as well as methods for the quantitative determination of peptides. Other chapters provide detailed information on the analysis of glycoproteins and glycopeptides and on the use of mass spectrometry to probe the interactions of proteins, both covalent and noncovalent.

Customer Reviews:

A good hand-book on protein analysis by MS.......2000-04-21

"Protein and Peptide Analysis by Mass Spectrometry" is a very good handbook for beginners, as well as experienced people. It is written by some of the best world specialists in the field. Volume 61 of the famous "Methods in Molecular Biology" series, it is built on the usual format: Introduction, Materials, Methods and Notes. Very clear and very practical, this up-to-date book should content most people interested in protein analysis.

HPLC of Peptides and Proteins: Methods and Protocols (Methods in Molecular Biology)

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HPLC of Peptides and Proteins: Methods and Protocols (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0896039773

Book Description

Hands-on experts from academia and industry comprehensively describe how to successfully perform all the critical HPLC techniques needed for the analysis of peptides and proteins. The methods range from commonly used techniques to those for capillary to large-scale preparative isolation. The authors have also presented a number of specific applications as case studies to illustrate the analytical approaches to a particular separation or assay challenge, with examples drawn from contemporary fields in biochemistry and biotechnology.

Peptide Synthesis and Applications (Methods in Molecular Biology)

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Peptide Synthesis and Applications (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 1588293173

Book Description

Hands-on experts describe in step-by-step detail the key methodologies of contemporary peptide synthesis and illustrate their numerous applications. The techniques presented include protocols for chemical ligation, the synthesis of cyclic and phosphotyrosine-containing peptides, lipoamino acid- and sugar-conjugated peptides, and peptide purification and analyses. Additional chapters detail methodologies and instrumentation for high-throughput peptide synthesis, many different applications of peptides as novel research tools and biological probes, and the design and application of fluorescent substrate-based peptides that can be used to determine the selectivity and activity of peptidases. A practical guide to the identification of proteins using mass spectrometric analyses of peptide mixtures is also included.

Amino Acids, Peptides and Proteins (Specialist Periodical Reports)

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Amino Acids, Peptides and Proteins (Specialist Periodical Reports)
G T Young
Manufacturer: Royal Society of Chemistry
ProductGroup: Book
Binding: Hardcover

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Amino Acids, Peptides and Proteins (Specialist Periodical Reports)
R C Sheppard
Manufacturer: Royal Society of Chemistry
ProductGroup: Book
Binding: Hardcover

Amino Acids: Chemistry, Biology and Medicine

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Amino Acids: Chemistry, Biology and Medicine

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

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Book Description

The investigation of amino acids is of fundamental interest to scientists from many diverse fields. This interest derives from their role as the basic constituents of proteins in addition to their ability to serve as building blocks for the production of many classes of secondary metabolites. They can support the biosynthesis of a myriad of natural products including non-protein amino acids, cyanogenic glycosides, pharmacologically active alkaloids, certain phenols, purines and pyrimidines, nucleic acids. condensed tannins, lignins and other metabolites. The contributions contained in this work originate from the First International Congress in Amino Acid Research. This collection of papers will appeal to researchers in the fields of biochemistry, vascular and cell biology, physiology, pharmacology, endocrinology and clinical medicine.

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Antisense Nucleic Acids and Proteins
Mol
Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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Book Description

A compilation of papers from many different scientific meetings in recent years, this reference source reviews the use of antisense nucleic acids to modulate or down-regulate gene expression, provides clues on the action mechanism of sense and antisense genes as well as data on antisense nucleic aci

Book Description

Responding to an estimated 14 million cases of food-borne disease that occur every year in the United States alone, the Food and Drug Administration and US Department of Agriculture have begun implementing new regulations and guidance for the microbial testing of foods. Similarly, Europe and other regions are implementing stricter oversight, as foodborne pathogens that cause deadly diseases such as e. coli 0157:H7 have raised the stakes everywhere. Food safety scientists have acted on this growing public health risk by developing improved media for the cultivation of bacteria, fungi, and viruses, much of it geared toward specific rapid detection. Reflecting the development of these new media and the latest FDA recommendations, the second edition of the Handbook of Microbiological Media for the Examination of Food provides an essential resource for anyone involved with the monitoring of both food production and post-production quality control. Organized alphabetically by medium, the expanded edition of this highly respected handbook includes - · Descriptions of nearly 1,400 media including those recommended by the FDA, as well as media used elsewhere in the world · Concise and lucid instructions for the preparation and uses of each of the media · Cross-referenced indexing that allows the media to be found by name or specific microorganism of interest · Descriptions of expected results as they apply to microorganisms of importance for the examination of foods · Common synonyms for the various media and listings of compositions, so that alternate media an be effectively employed when needed Compiled by Ronald M. Atlas, a world-renowned researcher and author known for his pioneering work in pathogen detection, the Handbook of Microbiological Media for the Examination of Food, Second Edition, provides microbiologists with an essential tool for safeguarding public health.

Handbook of Microbiological Media, Second Edition

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Hany in any Microbiology Lab

Handbook of Microbiological Media, Second Edition
Ronald M. Atlas
Manufacturer: CRC-Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0849326389

Book Description

This second edition of CRC's bestselling Handbook of Microbiological Media carries on the CRC tradition of handbook excellence. In this updated edition, media are included from virtually all international collections of microorganisms. The Handbook includes formulations and uses of more than 3,500 media used for isolation, culture, identification, and maintenance of microorganisms.

Customer Reviews:

Hany in any Microbiology Lab.......2000-06-15

The Handbook is an enormous tome of media formulations. The index is the back is indepensible. One thing that would have improved the volume is more explaination of why certain components are in each media formulation. However, this is for sure a useful book for all who work in microbiology, from clinical labs to industrial to academia.

Book Description

After an introduction into the historical development of science in 19th and 20th century Vienna, Schrödinger's early work on kinetic theory, atmospheric electricity, and on the atomic structure of solids, as well as his papers on statistical physics, general relativity and finally his concern with philosophy is presented. In the second chapter Schrödinger's activities in Zürich are described: atomic structure, the radiation problem and his important work on statistical mechanics.

Amazon.com

Christmas in bounty hunter Stephanie Plum's world isn't quite like Christmas in Whoville. With only four days to go before December 25, she doesn't have a decorated tree in her apartment or any presents bought. Plus she's chasing an elusive bail-jumper named Sandy Claws; a hunky guy named Diesel is literally popping in and out of her apartment; and a mob of manic elves is threatening to assault her with cookies. The end result is that Stephanie is feeling a tad stressed over the holiday season. Life isn't any calmer over at her parents' home in the Burg, where Grandma Mazur is dating a new octogenarian stud muffin; sister Valerie is wailing over some unwelcome news; and Stephanie's mother is coping by belting back tumblers of Red Roses in the kitchen. Just where is the elusive Mr. Claws hiding, and why? What's causing the power blackouts all over Trenton? And what about the mysterious villain, Mr. Ring? Is all of this real, or is Stephanie just having a very bad dream?

Janet Evanovich's mysteries are eagerly awaited by fans everywhere and this holiday installment won't disappoint. With a returning cast of entertaining, quirky characters and a rock-solid setting in New Jersey wrapped around an intriguing mystery, Evanovich delivers yet another hilarious adventure featuring irrepressible bounty hunter Stephanie Plum. --Lois Faye Dyer

Book Description

It's five days before Christmas and things are not looking merry for Fugitive Apprehension Agent Stephanie Plum. She hasn't got a tree. She hasn't bought any presents. The malls are jam-packed with staggering shoppers. There's not a twinkle light anywhere to be seen in her apartment-and there's a strange man in her kitchen.Sure, this has happened to Stephanie Plum before. But this guy is different. He's mysterious, sexy-and has his own agenda. His name is Diesel, and he's on a mission. The question is, what does he want with her? Can he help her find a little old toy maker who has skipped out on his bail right before Christmas? Can he survive the Plum family holiday dinner? Can he get Stephanie a tree that doesn't look like it was grown next to a nuclear power plant? These questions and more are keeping Stephanie awake at night. Not to mention the fact that she needs to find a bunch of nasty elves, her sister Valerie has a Christmas "surprise" for the Plums, her niece Mary Alice doesn't believe in Santa anymore, and Grandma Mazur has a new stud muffin. So bring out the plastic reindeer, strap on your jingle bells, and get ready to celebrate the holidays-Jersey style.

Customer Reviews:

Janet, Janet, Janet.......2007-10-09

I was disappointed in this novella having read the entire series of Plum books. No Ranger, Hardly any Morelli and some guy named Diesel who "pops in and out". The story was not believable and the wedding at the end was ridiculous.
Janet, Janet Janet-Please keep Stephanie and the characters that surround her more convincing.

Quick fun!.......2007-08-17

I especially loved this short novel. It was fast, fun, and rang in the holiday spirit! Read it two years ago during Christmas; it's become a holiday tradition and a relaxing break for myself during the busy holiday season! Draw yourself a bubble bath, grab the book, and head for the tub. It's a great escape and you deserve it! Enjoy!

What was Janet Evanovich thinking? Oh I know, let me rip off my fans and make a quick buck..........2007-07-29

I have read the first four books from the Stephanie Plum series and found them rather enjoyable. This book however is awful. It is quite obvious that this book was written in lightning speed with not much thought or editing. I was quickly becoming a fan of Janet Evanovich but this book has turned me away from her slightly.

I was disappointed.......2007-05-24

I love the Stephanie Plum books but I didn't like this one enough to finish it. I'll stick to the number books and pass on the specials from now on. I didn't like the Thanksgiving one either.

Pretty Good Read.......2007-05-06

Janet Evanovich is a great Author. I was disappointed in this Christmas book, however. It seemed that she had rushed to meet the deadline or something. Just not as good as all the others. I did however enjoy reading another book from one of my favorite authors.

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Visions of Sugar Plums
Janet Evanovich
Manufacturer: Penguin Audiobooks
ProductGroup: Book
Binding: Audio CD

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ASIN: 014180503X

Visions Of Sugar Plums - A Stephanie Plum Holday Novel

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Visions Of Sugar Plums - A Stephanie Plum Holday Novel
Janet Evanovich
Manufacturer: St. Martin's Press
ProductGroup: Book
Binding: Hardcover
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ASIN: B000MTRQHY

AMAZING STORIES - Volume 61, number 4 - November Nov 1986: Pleasure Palace; Fungo the Unrighteous; Human Affairs; Came Up Running; Lotion Sickness; Third Time Lucky; And Visions of Sugar Plums; Tremarest; Uranus, JPL and I; Cinemasaurus Rex

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AMAZING STORIES - Volume 61, number 4 - November Nov 1986: Pleasure Palace; Fungo the Unrighteous; Human Affairs; Came Up Running; Lotion Sickness; Third Time Lucky; And Visions of Sugar Plums; Tremarest; Uranus, JPL and I; Cinemasaurus Rex
Patrick Lucien (editor) (Lillian Stewat Carl; Reginald Bretnor; Robert Coulson; Forest Arthur Ormes; Bradley Stites; T. S. Huff; Sharon N. Farber; Keith Roberts; Gene DeWeese; Baird Searles; Professor Arthur L. Klein; Andrew Joron) Price
Manufacturer: TSR - Birthright
ProductGroup: Book
Binding: Paperback
ASIN: B000IA84KA

Hard Eight: To The Nines; Ten Big Ones; Eleven on Top; Twelve Sharp; Plum Lovin; & Visions of Sugar Plums (Stephanie Plum Novels, 7 Books by Janet Evanovich)

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Hard Eight: To The Nines; Ten Big Ones; Eleven on Top; Twelve Sharp; Plum Lovin; & Visions of Sugar Plums (Stephanie Plum Novels, 7 Books by Janet Evanovich)
Janet Evanovich
Manufacturer: St. Martin's Press
ProductGroup: Book
Binding: Hardcover
ASIN: B000WSHCYM

Karo Holiday Treasury (Favority All Time Recipes)

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Karo Holiday Treasury (Favority All Time Recipes)

ProductGroup: Book
Binding: Spiral-bound
ASIN: 0785310479

Stephanie Plum Series: One for the Money, Two for the Dough, Three to Get Deadly, Four to Score, High Five, Hot Six, Seven Up, Hard Eight, To the Nines, Ten Big Ones, Eleven on Top, Twelve Sharp, Visions of Sugar Plums (Set of 13 Mystery Novels)

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Stephanie Plum Series: One for the Money, Two for the Dough, Three to Get Deadly, Four to Score, High Five, Hot Six, Seven Up, Hard Eight, To the Nines, Ten Big Ones, Eleven on Top, Twelve Sharp, Visions of Sugar Plums (Set of 13 Mystery Novels)
Janet Evanovich
Manufacturer: St. Martins Paperbacks
ProductGroup: Book
Binding: Mass Market Paperback
ASIN: B000PJN3JQ

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VISIONS OF SUGAR PLUMS
JANET IVANOVICH
Manufacturer: Unknown
ProductGroup: Book
Binding: Hardcover
ASIN: B000SI94OC

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VISIONS OF SUGAR PLUMS
Janet Evanovich
Manufacturer: St. Martin's Press
ProductGroup: Book
Binding: Paperback
ASIN: B000OTDV3K

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Visions of Sugar Plums
Mimi Sheraton
Manufacturer: Random House
ProductGroup: Book
Binding: Hardcover
ASIN: B000WII8RC

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