Sensory Mechanisms of the Spinal Cord: Volume 1: Primary Afferent Neurons and the Spinal Dorsal Horn

Book Description

This text provides an historical and contemporary overview of an active field of neuroscience research on somato-visceral sensation. Medical (and indirectly veterinary) implications are emphasized. Extensive revisions have been made since the last edition, including the addition of two chapters. Many significant literature citations have been added for the period since the last edition. The illustrations have been substantially expanded, including a number that emphasize newly applied techniques.

Neural Stem Cells for Brain and Spinal Cord Repair (Contemporary Neuroscience)

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Neural Stem Cells for Brain and Spinal Cord Repair (Contemporary Neuroscience)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 1588290034

Book Description

Active neuroscientists survey NSCs as potential tools for central nervous system and spinal cord repair by explaining their clinically significant fundamental properties, manipulations, and potential therapeutic paradigms. Their discussion of the fundamental biology of NSCs illustrates the signaling pathways that regulate stem cell division and differentiation, and defines the methods of NSC expansion and propagation, neuromorphogenesis, the factors determining cell fate both in vitro and in situ, and the induction of self-reparative processes within the brain. They also present strategies that may lead to fruitful clinical applications in the near future. These range from the replacement of degenerated, dysfunctional, or maldeveloped cells to the provision of factors that may protect, correct, recruit, promote self-repair, or mediate the connectivity of host cells.

In Search of the Lost Cord: Solving the Mystery of Spinal Cord Regeneration

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Fascinating...
A medical book that reads like a mystery

In Search of the Lost Cord: Solving the Mystery of Spinal Cord Regeneration
Luba Vikhanski
Manufacturer: National Academy Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0309074371

Book Description

In Search of the Lost Cord is a scientific detective story, the stuff of science fiction en route to science fact. People trapped by the limitation of paralyzed limbs, rendered useless by devastating, catastrophic injuries to their spinal cords, may one day walk again. If the research is successful . . . if the scientists hit on the right strategy for approaching the problem, we may yet see miracles happen.

In her new book, science journalist Luba Vikhanski profiles the rapidly developing field of spinal cord injury research. She explains the field's greatest scientific challenges and introduces us to the pioneers who are working toward what would be a startling breakthrough. Perhaps the most riveting aspect of this international effort is the fact that each of these scientists is approaching the problem in very different ways. In the worldwide race to claim the prize of a cure, we witness a drama in the making.

Who will cross the finish line first? Will it be the Swiss scientist Martin Schwab, who has actually managed to heal spinal cords in rats and has restored their ability to walk? Will it be Wise Young, a Rutgers scientist who is pinning his research hopes on drug therapies? Or could Lars Olson of the Swedish Karolinska Institute hold the key to success in his efforts to construct a bridge of slender nerve filaments to connect a once-severed spinal cord? His rats are already flexing their legs.

These scientists, and others with unique and creative approaches of their own, have dared to tackle this seemingly unsolvable problem of spinal cord regeneration. Like all major medical and scientific breakthroughs, the “Eureka” moment often seems obvious in hindsight. Perhaps we'll have the same perspective when the puzzle of spinal cord regeneration is solved and the nerves are indeed healed. Until that time, there's a race to the finish line, and suspense is building. In Search of the Lost Cord is a trackside seat.

Customer Reviews:

Fascinating..........2007-06-02

Rarely do I read such an informative and riveting account of a scientific topic. I read it cover to cover and wanted to know more. It is a very comprehensive and satisfying history of spinal cord research!

A medical book that reads like a mystery.......2002-01-26

In this extremely well written book, Luba Vihanski reviews one hundred years of research on spinal record regeneration. She describes the many angles from which this topic has been approached. She explains what was previously believed and what the experiments demonstrated. Many diagrams and photographs make the topic more clear. The researchers involved are not left out in the dark: You get a feeling that you know them.

Book Description

There exists a wealth of information about the development of the spinal cord in journal articles and monographs, yet this beautifully illustrated work is the first book devoted to this important topic. Because the developing human spinal cord cannot be subjected to experimental manipulations, the knowledge gained from experimental work in animals is applied here to an interpretation of the time course and mechanisms of spinal cord development in man. The book begins with a review of our current understanding of the structure and functions of the spinal cord. Special reference is made to the phylogeny of the vertebrate spinal cord because the authors' interpretation of the development and organization of the human spinal cord is specifically an evolutionary one. Following a detailed experiment-based account of spinal cord development in the rat, the development of the human spinal cord is described, illustrated and interpreted in separate chapters during three epochs: the first trimester (the embryonic period), the second and third trimesters (the fetal period), and the first year of postnatal life. Special attention is paid to such topics as neurons, and the growth and myelination of the ascending and descending fiber tracts of the spinal cord. The book ends with a correlation of the development of motor behavior with different stages in the morphological development of the human spinal cord during the embryonic, fetal, and postnatal periods. The successive acquisition of voluntary control over different parts of the body during infancy is correlated with the progressive myelination of the corticospinal tract. * The book contains an extensive review of work on spinal cord organization and development throughout the 20th century. * The interpretations are based on experimental studies of spinal cord development in the rat carried out by the authors and their associates. * The histological material on human spinal cord development is the largest ever assembled and reproduced (combining the Carnegie, Minot, and Yakovlev Collections). * The collected material (which varies in quality and some of it has begun to fade) has been digitized and electronically reprocessed for improved reproduction. * Discrete components of the spinal cord and new developments are highlighted by color coding; typically on one side only, leaving the contralateral side untouched to allow the reader to use his own interpretation. * Summary graphs are presented, many in color, to convey important structural relationships, developmental events, or theories. * The authors revive a few forgotten theories and offer several new ones regarding the development and organization of the human spinal cord. Development of the Human Spinal Cord will be of interest to developmental biologists, neuroscientists, embryologists, molecular biologists (those working on stem cell research), pediatric neurologists, pathologists, child and developmental psychologists, and their students and trainees.

Form and Function in the Brain and Spinal Cord: Perspectives of a Neurologist (Issues in Clinical and Cognitive Neuropsychology)

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Form and Function in the Brain and Spinal Cord: Perspectives of a Neurologist (Issues in Clinical and Cognitive Neuropsychology)
Stephen G. Waxman
Manufacturer: The MIT Press
ProductGroup: Book
Binding: Paperback

Neuropsychology | Psychology & Counseling | Health, Mind & Body | Subjects | Books

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Book Description

This book reflects Stephen Waxman's three decades of research on the form and functions of the brain and spinal cord. Building on his experience as a neuroscientist studying model systems as primitive as eels and as a neurologist studying humans, Waxman discusses a wide variety of topics, including the design principles that optimize neural function; molecular and cellular substrates of behavior; the role of glial cells in the brain; the molecular basis for pain; plasticity in the brain and spinal cord; strategies for promoting functional recovery in disorders such as multiple sclerosis, spinal cord injury, and stroke; and prospects for rebuilding the brain and spinal cord. The pieces provide example after example of the elegance of design of the nervous system, of the intricate interplay between structure and function in health and disease, and of the rich borderland between neuroscience and neurology.

Stem Cells from Cord Blood, in Utero Stem Cells Development and Transplantation Inclusive Gene Therapy

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Stem Cells from Cord Blood, in Utero Stem Cells Development and Transplantation Inclusive Gene Therapy

Manufacturer: Springer-Verlag Telos
ProductGroup: Book
Binding: Hardcover

Embryology | Basic Science | Medicine | Subjects | Books

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Everybody Has a Bellybutton: Your Life Before You Were Born

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Great for kids, the artwork is exceptional

Everybody Has a Bellybutton: Your Life Before You Were Born
Laurence P. Pringle
Manufacturer: Boyds Mills Press
ProductGroup: Book
Binding: Hardcover

Anatomy & Physiology | Science, Nature & How It Works | Children's Books | Subjects | Books

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General | Baby-3 | Children's Books | Subjects | Books
ASIN: 1563970090

Customer Reviews:

Great for kids, the artwork is exceptional.......1998-06-21

The text is very informative and easily simplified when reading aloud to younger children. I thought the illustrations were warm and friendly, and beautifully done.

Autonomic Dysfunction After Spinal Cord Injury, Volume 152 (Progress in Brain Research)

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Autonomic Dysfunction After Spinal Cord Injury, Volume 152 (Progress in Brain Research)

Manufacturer: Elsevier Science
ProductGroup: Book
Binding: Hardcover

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ASIN: 0444519254

Book Description

Autonomic dysfunction is a major and poorly understood consequence of spinal cord injury. It is a cause of very serious disability and requires much more research. It should be a focus of treatment strategies. This book will be of interest to anyone involved in research and treatment of spinal cord injury since it helps to explain the tremendously negative impact on the body caused by cord injury that is not as obvious as paralysis and loss of sensation. It contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions.

The book begins with a description of the time course of autonomic dysfunctions and their ramifications from the first hours after a spinal cord injury to the more stable chronic states. The next section contains three chapters that address anatomical findings that may provide some of the foundation for autonomic dysfunctions in many of the systems. The system-specific chapters then follow in four sections. Each section begins with a chapter or two defining the clinical problems experienced by people with cord injury. The following chapters present research, basic and clinical, that address the autonomic dysfunctions.

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Cord Biology
Cord
Manufacturer: Globe Fearon
ProductGroup: Book
Binding: Hardcover

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Cord Biology Computer Test Bank
Cord
Manufacturer: Globe Fearon
ProductGroup: Book
Binding: Unknown Binding
ASIN: 0538683279

Book Description

The character of the Earth's surface is constantly changing as a result of the interactions of the great circulations of energy, water and materials that create the biogeochemical cycles between the atmosphere, hydrosphere, lithosphere, cryosphere and biosphere.

In addition human actions, from social and environmental interplay - often termed human ecology - have to be seen as part of a whole Earth system, impacting on biogeochemical cycles to produce feedbacks and responses. Some resulting impacts are readily expected, but others are less easily anticipated and all affect global environmental change.

The task of Volume Three of the Encyclopedia is to look at and analyse the interactions, feedbacks and causes from a holistic viewpoint and report upon some of the key aspects of human knowledge that are required for an integrated science.

Coverage includes:
* Human disturbance of the Earth system

* Global land cover and land use

* Global population trends

* Trends in global emissions

* Water use: Future trends, and environmental and social impacts

* Rice and its spread

* Environmental change and human health

* Environmental changes driven by civil conflict and war

Book Description

This volume of the Handbook is the second of a two-volume set of reviews devoted to the rare-earth-based high-temperature oxide superconductors (commonly known as hiTc superconductors).

Because of the rapid development of our knowledge of these materials, a review on this topic several years ago would have been hopelessly out of date even before the papers would be sent to the publisher. About five years ago the field began to mature, and it was felt it would be a good time to look into the possibility of publishing a series of review papers on rare-earth-containing hiTc superconductors.

In volume 31 we have ten chapters to complement the eight which appeared in print as volume 30 at the end of 2000 on the same topic.
These ten chapters are concerned with the electronic structure and various chemical, physical and optical properties of the hiTc oxides.

The first chapter is an extensive review of oxygen nonstoichiometry and lattice effects in Yba2Cu3Ox (YBCO). The next chapter concentrates on flux pinning effect which result in high critical current densities even at high temperatures and in high magnetic fields. The magnetoresistance and Hall effect in both normal and superconducting states of the cuprate superconductors are reviewed in chapter 3. The following two chapters are devoted to neutron scattering studies. And chapter 6 reviews some aspects of the low-temperature heat capacity of the ceramic oxide superconductors. The next three chapters are concerned with various spectroscopies - photoemission, infrared and Raman. Finally the tunneling spectra of the cuprate superconductors and the characterisation of these materials by scanning tunneling microscopy are discussed in chapter 10.

Book Description

In 1959, just one step ahead of the law, Ian Ferguson's parents left the sophisticated big-city life of Edmonton for Fort Vermilion — once a fur-trapping frontier town, now a remote aboriginal settlement in northernmost Alberta. There, Ian and his six brothers and sisters grew up without indoor plumbing, electricity, central heating, or even a radio. Beginning with the dramatic events surrounding his birth (including a paddlewheel ferry heading for destruction, a legendary rowboat trip, and a life-and-death race against time), the richly recalled events of Ferguson's life and a vivid array of characters make for a taut and appealingly idiosyncratic tale.

Customer Reviews:

A memorable case of growing up among lovable misfits .......2005-06-11

Written and narrated by author Ian Ferguson, Village Of The Small Houses: A Memoir Of Sorts is an hilarious and highly recommended account of growing up poor in the far north when in 1959, just ahead of the law, Ferguson's con-artist father Hank headed up north in a delapidated Mercury Zephyr with his pregnant wife, Louise. Hank got as far as isolated Fort Vermilion where he passed himself off as a teacher at the "Indian school" and settled his ever-expanding family in a house devoid of plumbing and electricity. The lively recounting of a scrappy childhood, Ferguson interweaves truth, tall-tale exag-geration, and a memorable case of growing up among lovable misfits in this 2 CD, 2 1/2 hour autobiographical account.

Interesting story set in the far north.......2005-04-08

The story here is about growing up in the far north. It begins in the 1950's when a con-artist father, Hank, leaves Edmonton with his pregnant wife and eventually passes himself off at the Indian school as a teacher. Hank settles his family in remote Fort Vermilion. The cast of loveable misfits struggle with the day-to-day harsh reality of being in Canada's third-poorest community. Winner of the Stephen Leacock Medal for Fiction

Brilliant!.......2004-10-14

I loved every page of this book. The writing is excellent and the story flows really well. There are so many moving moments in this book that I shed a tear on a number of occassions. I also laughed my head off quite a bit. What more can one ask of a memoir? Well done Ian!

Small houses-big characters.......2004-10-11

I read Ian Fergusons `biography of sorts` on a recent visit to Canada.The book was un-put-down-able,such well shaped characters,such wonderfully evoked scenery. Full of humour and pathos. When does the movie come out?

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