Large-scale Mammalian Cell Culture Technology (Biotechnology and Bioprocessing Series)

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An interdisciplinary approach, integrating biochemistry, biology, genetics, and engineering for the effective production of protein pharmaceuticals. The volume offers a biological perspective of large-scale animal cell culture and examines diverse processing strategies, process management, regulator

Animal Cell Culture and Technology : The Basics (Basics (Oxford, England).)

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Animal Cell Culture and Technology : The Basics (Basics (Oxford, England).)
Mike Butler
Manufacturer: BIOS Scientific Publ
ProductGroup: Book
Binding: Paperback

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ASIN: 1859960499

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The Basics series provide the ideal introduction to new techniques in the laboratory. This series of books will allow you to use the techniques described, and to manipulate them to suit your own basic requirements.

This book describes the basic requirements for establishing and maintaining cell cultures both in the laboratory and in large-scale operations. Minimal background knowledge of the subject is assumed and therefore it will be a readable introduction to animal cell culture for scientists intending to initiate some work in this field.

New topics are included to reflect the latest developments and trends in the field. They cover the latest theory of the biological clock (teleomeres) of cell lines, the development of improved serum-free media formulations, the increased understanding of the importance and control of protein glycosylation and the humanization of antibodies for therapeutic use.

Advances in Animal Cell Technology: Cell Engineering, Evaluation and Exploitation (Developments in Biologicals)

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Advances in Animal Cell Technology: Cell Engineering, Evaluation and Exploitation (Developments in Biologicals)
Guildford R. Spier
Manufacturer: S Karger Pub
ProductGroup: Book
Binding: Paperback

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Animal Cell Technology: Basic & Applied Aspects: Volume 8 (Animal Cell Technology)

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Anial Cell Technology: Basic & Applied Aspects:Proceedings

Animal Cell Technology: Basic & Applied Aspects: Volume 8 (Animal Cell Technology)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 0792344863

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Animal Cell Technology is a growing discipline of cell biology which aims not only to understand the structure, function and behavior of differentiated animal cells but also to ascertain their usefulness for industrial and medical purposes. The goal of animal cell technology includes clonal expansion of differentiated cells for practical applications, optimization of their culturing on an industrial scale, modulation of their ability for production of pharmaceutical proteins and monoclonal antibodies, and application to gene therapy and organ culture.
This volume gives a complete review of the state-of-the-art in Japan, a country where this field is particularly well advanced.
This book should be of interest to cell biologists, biochemists, molecular biologists, biochemical engineers and other disciplines related to animal cell culture, working in the academic environment, as well as in the biotechnology or pharmaceutical industry.

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Anial Cell Technology: Basic & Applied Aspects:Proceedings.......2000-10-22

i think it was really good. it help me understand animal cells better.

The Encyclopedia of Cell Technology, 2 Volume Set (Wiley Biotechnollogy Encyclopedias)

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The Encyclopedia of Cell Technology, 2 Volume Set (Wiley Biotechnollogy Encyclopedias)
Raymond E. Spier
Manufacturer: Wiley-Interscience
ProductGroup: Book
Binding: Hardcover

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ASIN: 0471161233

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Brings together up-to-date information on all key aspects of plant and animal cell technology in a single resource.
* Covers scientific, historical, and ethical aspects of biotechnology.
* Synthesizes a wealth of information in a valuable one-stop resource.
* Invaluable to researchers working animal or plant cell technology.

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Frontiers in Tissue Engineering

Manufacturer: Elsevier Science Pub Co
ProductGroup: Book
Binding: Hardcover

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ASIN: 0080426891

Book Description

Hardbound. Frontiers in Tissue Engineering is a carefully edited compilation of state-of-the-art contributions from an international authorship of experts in the diverse subjects that make up tissue engineering. A broad representation of the medical, scientific, industrial and regulatory community is detailed in the book. The work is an authoritative and comprehensive reference source for scientists and clinicians working in this emerging field.

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Consolidating and expanding current, fundamental notions of virology and animal cell cultivation, this practical reference examines the development of insect cell culture techniques for the production of recombinant proteins and insect pathogenic viruses.;Resolving on-the-job problems such as sparging cell damage and reduced infectivity cells, Insect Cell Culture Engineering: includes special introductory material as well as background information on insect pathogenic viruses, the molecular biology of baculoviruses and bioreactor design; offers advice on how to save time when deciding which insect cell line, bioreactor and medium to exploit; discusses the preparation of mathematical modelling in animal cell culture; addresses the concerns associated with insect cell immobilization and the use of serum-free culture media; provides insights into the protective effects of polymer additives and insect cell gene expression in pharmaceutical research; and analyzes process scale-up and reactor design.;Bridging the gap between laboratory research and pilot plant scale insect culture/baculovirus technology, Insect Cell Culture Engineering is designed as a reference for biochemical and bioprocess engineers, bioprocess technologists, biochemists, molecular and cell biologists, microbiologists, and upper-level undergraduate and graduate students in these disciplines.

Proceedings of the Fifth General Meeting of European Society of Animal Cell Technology (Developments in Biologicals)

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Proceedings of the Fifth General Meeting of European Society of Animal Cell Technology (Developments in Biologicals)
European Society of Animal Cell Technology General Meeting 1982 copen , F. Horaud , R. Spier , and B. Griffiths
Manufacturer: S Karger Pub
ProductGroup: Book
Binding: Paperback

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Reproductive Biotechnology in Finfish Aquaculture

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Reproductive Biotechnology in Finfish Aquaculture

Manufacturer: Elsevier Science
ProductGroup: Book
Binding: Hardcover

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ASIN: 0444509135

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The successful reproduction of cultured brood stock is essential to the sustainable aquaculture of aquatic organisms. This book describes recent advances in the field of finfish reproductive biotechnology. The chapters in this volume are written by eminent scientists who review the progress and assess the status of biotechnology research that is applicable to the reproduction of finfish species for aquaculture. A wide range of topics is included starting with broodstock technologies such as broodstock genetics, broodstock nutrition, environmental control of maturation and impacts of stress on broodstock, gametes and progeny.

The volume includes technologies for induction of ovulation and spermiation using synthetic hypothalamic peptides. Gamete technologies which are described include cryopreservation, chromosome set manipulation, disease prevention and control for gametes and embryos and the development of transgenic fish with enhanced production characteristics. Genetic and endocrine technologies for the production of monosex male and female fish stocks are also described.

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Prion diseases, also known as Transmissible Spongiform Encephalopathies (TSEs), exist in both humans (Creutzfeldt-Jakob disease (CJD)) and animals (scrapie, bovine spongiform encephalopathy (BSE), chronic wasting disease) and have the unique property of being infectious, sporadic or genetic in origin.
Although the precise nature of the infectious agent responsible for TSEs is not definitely identified, it is now clearly demonstrated that a protein named PrP (for Prion Protein) plays a critical role in the transmission and pathogenesis of TSEs.
This book provides the general description as well as the details of the techniques currently used for the study of prion diseases. Taking into account the pivotal role played by PrP it is not surprising that many Chapters of this book deal with the purification, the detection and the characterization of the different forms of this protein. In addition, in vitro, cellular and animal models specifically adapted to the study of TSEs, as well as bio-safety procedures are described. Each Chapter is written by scientists involved for many years in their respective domain of prion biology who give the best of their knowledge in this technical document. This volume is a very useful tool for any laboratory which recently decided to contribute to the study of TSEs as well as for teams already engaged in this field for many years but interested in extending their technical capacity toward new methods.

Features:
Purification of PrPC and the Pathological Isoform of Prion Protein (PrPsc or PrP-res)
Animal Models of TSEs
Cell Culture Models of TSEs
PrPsc Immunohistochemistry
Western Immunoblotting Techniques
Antibody Production and ELISA
TSE Strain Typing in Mice
Biosafety and Decontamination Procedures
Cell-free Conversion of Prion Proteins
Cytotoxicity of PrP Peptides
Cyclic Amplification of Prion Protein Misfolding

Book Description

Mud and mudstone, the most abundant of all sediments and sedimentary rocks, are relevant to many different human activities and disciplines and thus have a widely scattered literature. Our book provides the first elementary overview of mud and mudstone written for a broad spectrum of professionals, teachers and students in geology, petroleum geology and engineering, urban planning and development, paleontology and paleoecology, and architecture and archaeology. Mud and mudstone provide the foundations to master all their aspects and prepares you to dig deeply into the many fascinating questions of their origin, relationships to earth history and practical uses. Key topics include the production of mud, its transport, the important role of bottom oxygen, sites of deposition, burial, provenance, mudstones in basins and an overview of practical uses followed by an appendix and extended glossary.

Book Description

This volume is the first of a series on Physical Techniques in the Study of Art, Archaeology and Cultural Heritage. It follows a successful earlier publication by Elsevier (Radiation in Art and Archaeometry).

There has been an upsurge of interest world wide in cultural heritage issues, and in particular, large organizations such as UNESCO and the European Union are active in providing funding for a very diverse range of projects in cultural heritage preservation. It is perceived that it is essential to preserve the cultural heritage of societies, both to benefit the future generations of those societies, and to inform other cultures.

A growing need exists for the education of conservators and restorers because it is these professionals who will make decisions on how best to preserve our cultural heritage. This book series therefore has as its primary aim, the dissemination of technical information on scientific conservation to scientific conservators, museum curators, conservation science students, and other interested people.

Scientific conservation, as a discipline, is a comparatively modern concept. Interested scientists have for many years addressed scientific problems associated with cultural heritage artefacts. But their involvement has been sporadic and driven by the needs of individual museums, rather than a personal lifetime study of issues of conservation of for example, buildings, large functional objects, paintings, and so on.

In this book series contributors will come from both interested scientists and the museum-based scientists. The authors have been selected with an eye to involving young, and well as established, scientists.

Dr Jean Louis Boutaine, was Head of the Research Department of the Centre de Recherche et de Restauration des Musees de France at the Louvre. Dr Boutaine has had a most distinguished career within the conservation science community. He writes here on the concept of the Modern Museum.

Professor Casali is responsible for the teaching of Archaeometry at the University of Bologna. He has developed advanced equipment for both micro-Computer Tomography and for large-object Computer Tomography. His chapter deals with X-ray, neutron, and digital radiography as applied to the study of objects of cultural heritage significance.

Professor Tim Wess holds the Chair of Biomaterials in the Biophysics Division in the School of Optometry and Vision Science at Cardiff University. The systems in which he is interested contain collagen, fibrillin, and cellulose (which relate, in the cultural heritage discipline, to an interest in parchment and papers). A parallel interest is in the structure of bone and artificial composite materials (which relates to his interest in historical studies of bone materials). Chapter 3 will describe the techniques used to study alteration to structure of minerals in the bone. Preservation of intact bone mineral crystallites has been shown to relate to the endurance of amplifiable ancient DNA from archaeological and fossil bone. In collaboration with Drs K. Nielsen and Rene Larsen (School of Conservation, Copenhagen, Denmark) Tim Wess has analyzed the deterioration of historic parchments and also simulated ageing processes.
Chapter 5 has been written by Dr Andrew Hardy who began studying Middle Eastern eye cosmetics (kohls) in the early 1990's whilst working in Oman. He has continued this work at the Centre for Medical History, School of Historical, Political and Sociological Studies, Exeter University. The chapter summarizes and reviews the usage and composition of kohls in ancient (Pharaonic) Egypt. It also gives information, from later time periods, on kohl usage and its recipes, which have been studied using a wide range of experimental techniques.

· Written in a style that is readily understandable by conservation scientists, archaeologists, museum curators, and students
· Provides an introduction to the advanced fields of synchrotron radiation science, neutron science, and computed tomography
· Outstanding review of the use of modern technology to study museum and archaeological artifacts
· Offers solutions through advanced scientific techniques to a wide range of problems facing museum staff

Physical Techniques in the Study of Art, Archaeology and Cultural Heritage, Volume 1

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Physical Techniques in the Study of Art, Archaeology and Cultural Heritage, Volume 1
David; Creagh,Dudley Cecil Bradley
Manufacturer: Elsevier
ProductGroup: Book
Binding: Paperback
ASIN: B000N5L1MS

Book Description

When identical twins Judy (smart businesswoman) and Jana (a desperate housewife) swap places trouble ensues.

Identical twins and former child stars of a Barney–like program, Judith and Jana Lee Tompkins have barely spoken to each other in ten years, when Judith stole Jana Lee's fiancé in college (and all hell broke loose as a result).

But now Judith is in a personal crisis, and she desperately needs Jana Lee to come take her place in her high–powered career so no one at the office will know she's cracking up. Jana, now a young widow whose life seems to be on hold, says yes in the hopes that she can leave Judy's life in better shape than she found it, and also find out what a life as a powerful city girl would have been like. Judy takes Jana's place in their childhood home running the old homestead–a much tougher job than she ever imagined.

But as problems crop up in corporate and home life, Jana and Judy find out that the grass is always greener, and life for both displaced twins proves to be quite a challenge. Hardest of all is resisting the men the other women left behind... but these two are about to find out the bad–old–days of college are over, and maybe what is Mr. Wrong for one sister might be Mr. Right for the other!

Customer Reviews:

Overused plot produces a charming story.......2006-11-29

Jana Lee lost her husband two years ago. A single widowed mom, she lives a quiet existence in the Washington state hometown she and her identical twin were raised in - heck - even the same house. When a very frazzled Jillian begs Jana Lee to switch places with her like they used to do as kids, she balks at first - after all the last time they did that, Jillian ran off with Jana Lee's fiance! But in the interest of placating her sister, she agrees and enters the big world of finance in San Francisco.

While working at Pitman Toys, she captures the eye of the VP who Jillian dry humped at the office Christmas party. But for some reason, Jackson is suddenly attracted to his CFO... As he chases her down, she flees, making the chase all the more sweet, and the gossip hounds more angry. When her fresh ideas outside the financial arena make everyone take notice, Jana Lee wonders if sedate Washington is what she wants.

Meanwhile, Jillian is supposed to be relaxing but instead tries to do a total house makeover for Jana Lee with the help of sexy sculptor Dean Wakefield and niece Carly. He's wondering what's gotten into the usually sedate and earthy widow, and when he comes across a picture of the twins, he realizes they've switched.

MacPherson has penned another charming romantic comedy with a fair amount of romance. The overused twin swap plot is not as bad as one would imagine, and MacPherson manages to breath a distinct personality into each of women, making for a charming story about taking a second chance.

Highly Entertaining.......2006-07-30

This book was great for a good laugh. The characters are hillarious! I would recommend this to anyone over the age of about 16.

Entertaining and different.......2006-04-06

This is a great fun read that will have you laughing at the situations these two twins get themselves involved in. Real characters with real situations and feelings. I definitely recommend this one!

screwball romantic romp .......2005-11-30

After beating up the candy machine at work, stressed out Jillian Tomkins is given a week off to unwind at Serenity Spa where she pleads with her twin sister Jana Lee Tompkins Stivers to switch places like they used to until that final incident with Elliot the idiot in college led to an estrangement. The death of Jana Lee's husband led to a partial reconciliation, but the widow mother of a teen, sees a chance to escape her drudgery and further repair her relationship with her twin. Though she thinks they are doomed, she agrees.

In San Francisco at Pitman Toys, Jana Lee as Jillian immediately runs into trouble with every high heel step she takes as VP Jackson "Man-Zinger Hawks seems to desire her as he admits to himself she seems different, earthier than the corporate climber who jumped his bones last Christmas. At the same time Jillian as Jana Lee soon learns the craziness of life in the burbs from Carly the irritable and aloof teenage niece, the insane dog, and appliances that requires an engineering degree not an MBA. If she does not burn down her sister's home, Jillian's biggest zinger is repairman Dean Wakefield, who suddenly finds Jana Lee appealing.

This screwball romantic romp is a comical tale as the sisters struggle to survive what to each one is a foreign lifestyle. The twins make the tale appealing even while the audience along with Jackson wonders why Jillian could not ask for additional time off. This comedy of errors is fun as the two men suddenly in the twins' lives wonder how they missed the endearing qualities they suddenly have discovered. Fans will feel amused, absorbed and bewitched.

Harriet Klausner

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Switched, Bothered and Bewildered
Suzanne MacPherson
Manufacturer: Avon books
ProductGroup: Book
Binding: Hardcover
ASIN: 073945997X

Product Description

354 pages

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Switched, Bothered and Bewildered
Suzanne Macpherson
Manufacturer: Avon
ProductGroup: Book
Binding: Paperback
ASIN: B000OERS20

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