Prokaryotic Gene Expression (Frontiers in Molecular Biology)

Book Description

Prokaryotic gene expression is not only of theoretical interest but also of highly practical significance. It has implications for other biological problems, such as developmental biology and cancer, brings insights into genetic engineering and expression systems, and has consequences for important aspects of applied research. For example, the molecular basis of bacterial pathogenicity has implications for new antibiotics and in crop development. Prokaryotic Gene Expression is a major review of the subject, providing up-to-date coverage as well as numerous insights by the prestigious authors. Topics covered include operons; protein recognition of sequence specific DNA- and RNA-binding sites; promoters; sigma factors, and variant tRNA polymerases; repressors and activators; post-transcriptional control and attenuation; ribonuclease activity, mRNA stability, and translational repression; prokaryotic DNA topology, topoisomerases, and gene expression; regulatory networks, regulatory cascades and signal transduction; phosphotransfer reactions; switch systems, transcriptional and translational modulation, methylation, and recombination mechanisms; pathogenicity, toxin regulation and virulence determinants; sporulation and genetic regulation of antibiotic production; origins of regulatory molecules, selective pressures and evolution of prokaryotic regulatory mechanisms systems. Over 1100 references to the primary literature are cited. Prokaryotic Gene Expression is a comprehensive and authoritative review of current knowledge and research in the area. It is essential reading for postgraduates and researchers in the field. Advanced undergraduates in biochemistry, molecular biology, and microbiology will also find this book useful.

Chromosomal Mutagenesis (Methods in Molecular Biology)

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Chromosomal Mutagenesis (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

Genetics | Evolution | Science | Subjects | Books

Biochemistry | Basic Science | Medicine | Subjects | Books

Book Description

Great disparities exist between organisms with regard to the relative ease of chromosomal mutagenesis and manipulation. In Chromosomal Mutagenesis, a team of experts provide a variety of chromosomal manipulation techniques, including insertional gene disruptions, gene knockouts, stimulated homologous recombination techniques and other novel tools, for both prokaryotic and eukaryotic organisms, and attempt to expand the genetic toolbox beyond model organisms. Following the format of the highly successful Methods in Molecular Biology™ format, each chapter offers step-by-step laboratory instructions, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.

Comprehensive and cutting-edge, Chomosomal Mutagenesis covers state-of-the-art techniques that are staged to expand, if not revolutionize, genetic analysis in the long neglected and relevant cell types.

DNA Repair Protocols: Prokaryotic Systems (Methods in Molecular Biology)

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DNA Repair Protocols: Prokaryotic Systems (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

Genetics | Evolution | Science | Subjects | Books

General | Science | Subjects | Books

Biochemistry | Basic Science | Medicine | Subjects | Books

Genetics | Basic Science | Medicine | Subjects | Books

Book Description

Well-versed investigators describe in step-by-step detail a wide range of DNA repair activities, from single act-alone repair proteins to complex repair systems. These practical protocols not only detail the various repair activities found in cells, but also demonstrate the use of DNA repair proteins and systems as reagents in molecular biology and biotechnology. The techniques described here include mutation and polymorphism detection, which are useful in the search for disease genes and drug response genes, as well as for breeding and trait selection in animals and plants. Compact and highly practical, DNA Repair Protocols: Prokaryotic Systems provides expert guidance to both the DNA repair researcher studying the fundamental aspects of DNA repair and the applied researcher in human genetics and biotechnology.

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Organization of the Prokaryotic Genome

Manufacturer: ASM Press
ProductGroup: Book
Binding: Hardcover

Genetics | Evolution | Science | Subjects | Books

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Bacteriology | Agricultural Sciences | Science | Subjects | Books

Microbiology | Basic Science | Medicine | Subjects | Books

Book Description

The field of genomics has seen dramatic expansion in the years following the publication of the prokaryotic genome. Must of the present effort in genomics lies in sequence production, annotation, and other bioinformatic analyses and in the beginnings of genetic and biochemical characterization of ORFs.

Organization of the Prokaryotic Genome contributes to the field by examining the importance of the gene organization in the genome and its role in the shaping of life. Intended to review and direct progress in our understanding of genome organization, this book explores the way in which genes interact with their neighbors.

Book Description

Prokaryotic Genomics provides molecular microbiologists in particular and researchers working with bacteria in general with the most important established recipes needed for their work. The volume covers both revisited classical methods and new tools for global analysis such as genomics or proteomics. It is written for those in need of a bench manual to complete their experiments and for those wanting to understand the modern tools used in microbiology.

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Prokaryotic Genomics
Michael Blot
Manufacturer: Springer (India) Private Limited
ProductGroup: Book
Binding: Paperback
ASIN: 8181281993

Book Description

Lindenmayer Systems are a mathematical formalism which was proposed by Aristid Lindenmayer in 1968 as a foundation for an axiomatic theory of development. This book presents the application of Lindenmayer Systems and Fractal Geometry to graphics-based plant modelling, a fascinating approach to visualizing growth functions in plants. For life scientists, mathematicians and computer scientists alike, this book will provide a unique and stimulating view at an interdisciplinary field of science.

Customer Reviews:

Lecture Notes in Biomathematics??.......2000-09-19

Well this gem of a book is hidden away in the biology section of my local library. Not the easiest of places for somebody interested in computer graphics to find.

This book is a great place to start if your looking for an introduction to 2D and 3D plant/organism structural modelling using computer graphics, such as modelling plant and leaf structures as well as bacteria and the like. It discusses the various types of Lindenmayer Systems and has some program code in the appendix, though the code is of poor quality.

Book Description

This volume delineates the use of fractal patterns and measures of fractal dimensions in describing and understanding general aspects of biology, particularly human physiology. After describing the ubiquitous nature of fractal phenomena, the authors give examples of the properties of fractals in space and time. Proceeding from mathematical definitions, they develop detailed practical methods for assessing the fractal characteristics of wave forms varying with time, tissue density variation, and surface irregularities. Most importantly, the authors show how fractal variation defines internal spatial or temporal correlations within the fractal system or object. Simple, recursively applied rules can give rise to complex biological structures by a variety of methods. This suggests that genetic rules govern the general structuring of an organism, while rules implied by interactions at the biochemical, cellular, and tissue levels govern ontogenic development and therefore play the major role in the growth of an organism. Chaos, or non-linear dynamics, is introduced as a stimulating way to examine biological behavior at the cellular and whole animal levels, even though proof of the chaotic nature of normal physiologic events is as yet meager. The later chapters give sets of examples of structural and behavioral fractal phenomena in nerve and muscle, in the cardiovascular and respiratory systems and in growth processes. Why molecular interactions and complex systems give rise to fractals is explored and related to the ideas of emergent properties of systems operating at high levels of complexity.

Fractal Physiology and Chaos in Medicine (Studies of Nonlinear Phenomena in Life Science, Vol 1)

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Fractal Physiology and Chaos in Medicine (Studies of Nonlinear Phenomena in Life Science, Vol 1)
Bruce J. West
Manufacturer: World Scientific Pub Co Inc
ProductGroup: Book
Binding: Hardcover

Physiology | Basic Science | Medicine | Subjects | Books

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Fractals in Chemistry, Geochemistry, and Biophysics: An Introduction

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A breakthrough in the use of fractals !

Fractals in Chemistry, Geochemistry, and Biophysics: An Introduction
K.S. Birdi
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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General | Physics | Science | Subjects | Books

Mathematical Physics | Physics | Science | Subjects | Books

Geochemistry | Earth Sciences | Science | Subjects | Books

Book Description

In this introductory text, Dr. Birdi demonstrates experimental methods and analyses of fractal dimensions in natural processes. In addition to a general overview, he discusses in detail problems in the fields of chemistry, geochemistry, and biophysics. Both students and professionals with a minimum of mathematics or physical science training will learn to find and model shapes and patterns from their own everyday observations.

Customer Reviews:

A breakthrough in the use of fractals !.......1999-04-12

After having read this book I have changed my mind regarding fractals. I have always thought of fractals as a "smart" way of making maths popular. But Professor Birdi's book really links maths, Chemistry an Physics together in an new way. If you are a student, or if you work with related subjects you will benefit from the visionary point of view in the book.

Fractal Physiology & Chaos in Medicine (Studies of Nonlinear Phenomena in Life Science)

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Fractal Physiology & Chaos in Medicine (Studies of Nonlinear Phenomena in Life Science)
Bruce J. West
Manufacturer: World Scientific Pub Co Inc
ProductGroup: Book
Binding: Paperback

Physiology | Basic Science | Medicine | Subjects | Books

General | Medicine | Subjects | Books

All Titles | Qualifying Textbooks - Fall 2007 | Stores | Books
ASIN: 9810201281

Book Description

This book discusses the application of the concepts of fractals and chaos to biomedical phenomena. In particular, it argues against the outdated notion of homeostasis; using biomedical data sets and modern mathematical concepts, the author attempts to convince the reader that life is at least a homeodynamic process with multiple states - each being capable of survival. Although relying heavily on the new mathematical ideas, the author has attempted to make the book self-contained. The mathematics is developed in a biological context and mathematical formulation for its own sake is avoided. In this book, the phenomena to be explained motivate the mathematical development rather than the other way round.

Customer Reviews:

important history in a lace stocking.......2005-03-18

While renovating an old house, a person found a lace stocking filled with love letters from a woman to a man. Also enclosed is a photo of a black woman. Instead of being correspondence between two blacks, it turns out that these letters were written by an Irish-American woman to her black male lover.

History buffs and amateur genealogists should love this book. Outside of the interracial context, this book answers how do you find more information when you come upon a historical artifact. The answer is to look at old census documents, old maps, old magazines. Also, let people know what you found and see if someone may know helpful third parties. Just as modern techniques show that we leave our DNA everywhere, for approximately 150 years or so, Americans have left photographs and writings everywhere. Your reality can be found, even a century after the fact.

The editor of this book said that the contributors knew this book must be a collaboration from the start. I actually think a historian with a background in women's history, African-American history, and local Massachusetts history could have written this book all by her- or himself.

The extant letters were written by Alice to Channing; there is no existing two-way correspondence here. However, the book stated that when relationships fell apart, women often asked their paramours for their letters back. So while I thought that Channing may have kept these letters, it was actually Alice who did so. In that same vein, the book uncovers much more about Alice than Channing. In fact, it stands out that the chapter devoted to her is deep whereas the one devoted to him is scant. Still, you gotta work with whatcha got.

This book is inspiring in that it proves such relationships did exist before Loving v. Virginia. However, that is where the inspiration ends. This relationship was riddled with abuse, jealousy, "gold digging," and misogyny. Just as Frederick Douglass wed a different white woman than the one to whom he wrote love letters, Channing never divorced his white wife to marry Alice. Patricia Hill Collins has soundly condemned the idea that this pairing is Root's "love's revolution." That stands out here. In fact, modern census figures show that couples co-habit interracially much more than they wed interracially.

While this book does mention Smith College at several points, it never brings up that Northampton is now nicknamed "Lesbianville, USA" by its own residents. Greenwich Village was known for its tolerance toward interracial couples and gay couples. The authors here never state whether Northampton residents of that era would have been equally open-minded.

This book does leave some questions unanswered. Alice was 32 when she wrote to Channing and 40 when she married another man. Did she pursue Channing because she didn't want to be an "old maid"? Channing was obviously literate, but the authors never suggest how he learned to read. They mention several times that the Civil War was a close memory for all involved. During the slavery era, it was illegal to teach blacks to read. This book never answers how Channing became one of the exceptions.

Critics have complained that books don't bring up issues of race, class, gender, and sexuality enough. Well, this book juggles all of those balls. In fact, this book spells out ways that the interracial component of this duo may have been the smallest worry of the couple's concerns. Alice never brings up race in her letters, but the authors suggest that clearly race was a salient issue at this time. I am pleased that I found this book.

Love Across the Color Line: The Letters of Alice Hanley to Channing Lewis

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Love Across the Color Line: The Letters of Alice Hanley to Channing Lewis
Helen Lefkowitz and Kathy Lee Peiss, Editors Horowitz
Manufacturer: Univ. of Massachusetts Press
ProductGroup: Book
Binding: Hardcover
ASIN: B000N371P6

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