Histidine Kinases in Signal Transduction

Book Description

Living cells are constantly sensing environmental changes, and their abilities to sense these changes and adapt to them are essential for their survival. In bacteria, histidine kinases are the major sensors for these environmental stresses, enabling cells to adapt to new growth conditions.

Written by leading experts in the field, this book provides an up-to-date and comprehensive review on the structure and function of histidine kinases. It also provides extensive information on the physiological roles of histidine kinases in bacteria and eukaryotes.

An an essential reference for cell biologists, microbiologists, molecular biologists, and biochemists interested in signal transduction. Experimental biologists and pharmacologists studying signal transduction systems in living organisms will also find it a valuable research tool.

Key Features
* The first comprehensive book on the roles of histidine kinases in cells
* 23 in-depth chapters written by leading experts in the field
* Describes the most recent advances in the field of signal transduction

Histidine Kinases in Signal Transduction

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Histidine Kinases in Signal Transduction
Masayori Inouye
Manufacturer: Academic Press
ProductGroup: Book
Binding: Paperback
ASIN: B000OHYIUC

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Histidine Kinases in Signal Transduction
Masayori Inouye
Manufacturer: Elsevier Science & Technology Books
ProductGroup: Book
Binding: Hardcover
ASIN: B000MUWSEY

Book Description

Gain a working knowledge of thermodynamics and kinetics with a minimum of mathematics-a guide for individuals in the biological sciences

An understanding of thermodynamics and kinetics is essential for researchers investigating molecular phenomena in diverse disciplines, including bioorganic chemistry, medicinal chemistry, biochemistry, pharmaceuticals, and biology. The use of these physical chemistry tools in the biological sciences has exploded over the past fifteen years, but the majority of works on thermodynamics and kinetics require mathematical expertise beyond that of many researchers in the field. Presenting a highly accessible introduction to thermodynamics and kinetics, Thermodynamics and Kinetics for the Biological Sciences employs a minimum of mathematics, assuming only a basic calculus background, while treating a wide range of topics in a logical and easy-to-follow style. All principles and concepts are clearly illustrated through the use of relevant applications and examples from the biological sciences, and explanations are further enhanced with problems and up-to-date references. Written by a world-renowned authority on biochemical kinetics, this remarkable book also features an easy-to-understand statistical development of entropy and a more extensive coverage of chemical kinetics and ligand binding to macromolecules than is usually found in books of this kind. Readers will acquire a working knowledge of thermodynamics and kinetics that they can readily apply to biological systems and use for exploring the scientific literature.

Customer Reviews:

Excellent.......2001-05-12

I used this book as a supplement in a 4th semester chemistry course targeted for biology and premedical students this past term. It has excellent up-to-date examples and good problems. Hammes does a nice job of presenting at an appropriate level topics from thermodynamics and kinetics needed to read and understand biochemical articles. Such things as the meaning of the biochemical (as opposed to the chemical) standard state are particularly well done -- better than in other books I have seen for this audience.

But why does Wiley price [it at its cost]? Perhaps it is the nice color plates --- but at a lower price I would have had everyone in my class buy this as a suppplement to the text. At this price I am reluctant to do so.

Biologic Thermo without all the ideal gas BS.......2001-05-02

I enjoyed reading and studying this "thermodynamic/kinetics with a biochemistry twist". Most thermo books get too bogged down with ideal gases and the cost in time versus the benefits of material learned is too great. Dr. Hammes however has an easy reading style and focuses in on the "meat" of physical biochemistry pertaining to thermodynamics and kinetics. I am not a formal student, but a cardiologist interested in physical biochemistry. P-Chem learning requires doing the problems. The only drawback to Professor Hammes's textbook is that there are no solved problems or solutions manual for the problems in the back of each chapter. Nerds like me find these problems as a useful exercise in learning to insure that we have mastered the material. You will not be disappointed in this book.

Average customer rating:

good introductory work
Excellent starting for Biophysics

Biophysics
Roland Glaser
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 3540670882

Book Description

Biophysics - the science of physical principles of life itself, of biological systems - is presented here not merely as physics for biologists, but as an entirely independent subject with its own innate network of ideas and approaches. From the microscopic forces that constitute life, the intramolecular bonds and ionic interactions, to the macroscopic forces of the environment, temperature and pressure, the author presents and explains all aspects of life from a Biophysicist's point of view. Exciting biological themes such as neuronal processing and differentiation as well as current medical and environmental topics are introduced from a surprising perspective in this imaginative new textbook.

Customer Reviews:

good introductory work.......2004-09-20

This is a very thoroughly written introductory work for biophysics, an area where it is very difficult indeed to find intro-level textbooks.

Both biologists and physicists will find many new things worth exploring, and this book will certainly provide the basics for further research and study. It isn't the ten volume all-you-will-ever-want-to-know-about-biophysics, but whichever area You are starting to work with, from membrane transport to biomechanics, have a look at this book first.

Excellent starting for Biophysics.......2003-09-22

This book is written by a biologist. However, the author discussed lots of physics topics closely related to basic biological phenomena. The most important role of this book, I believe, is making the bridge between physics and biology as well as biochemistry. Untill now, most of biophyiscs text books have been a kind of biochemsitry text book like ones. This one is distingusihed from those. This is also good for biochemistry student who wants to study physical aspects of biological system beyond the scope of biochemistry. Some parts of this book might be difficult for biology and biochemistry students but surely deserves to be read.

Physical Chemistry for the Biological Sciences (Methods of Biochemical Analysis)

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Physical Chemistry for the Biological Sciences (Methods of Biochemical Analysis)
Gordon G. Hammes
Manufacturer: Wiley-Interscience
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

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Structure and Mechanism in Protein Science: A Guide to Enzyme Catalysis and Protein Folding

ASIN: 0470122021

Book Description

Gain a practical, working knowledge of the physical chemistry essential for the biological sciences

Physical Chemistry for the Biological Sciences is an excellent resource for biochemistry and biology/health science professionals and students who need a basic understanding of thermodynamics, kinetics, hydrodynamics of macromolecules, and spectroscopy in order to explore molecular structure and chemical reactions. Approachable, yet thorough, the book presents physical chemistry in conceptual terms with a minimum of mathematics. Providing the basic knowledge and tools that every biologist should have to understand the quantitative interpretation of biological phenomena, it covers:

Fundamentals of thermodynamics and chemical kinetics
Fundamentals of spectroscopy and structure determination
Ligand binding to macromolecules, hydrodynamics, and mass spectrometry

Book Description

This three-part treatment translates the technical language of research monographs on the theory of free energy transfer in biology, making the subject more accessible to those entering the field. Designed for upper-level classes in biochemistry or biophysics, it can also be used for independent study. 36 figures. 1989 edition.

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A Primer on Nonequilibrium Thermodynamics in Biochemical Systems.......2007-08-01

Catalytic cycles associated with enzymes and transporters transfer free energy between different substances and forms in cells. The mechanisms, efficiencies, and overall operation of catalytic cycles represent the basic concerns of much of the author's important and influential scientific career. This elegant and accessible monograph provides the perfect introduction to the subject in three chapters.

Kinetics and thermodynamics in biochemistry,

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Kinetics and thermodynamics in biochemistry,
H. Geoffrey Bray
Manufacturer: Academic Press
ProductGroup: Book
Binding: Unknown Binding

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Kinetics and Thermodynamics in Biochemistry.
H. Geoffrey & White, Kenneth. Bray
Manufacturer: Academic Press
ProductGroup: Book
Binding: Unknown Binding
ASIN: B0000CJMHL

Thermodynamics and Kinetics for the Biological Sciences/Spectroscopy for the Biological Sciences; 2-book Set

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Thermodynamics and Kinetics for the Biological Sciences/Spectroscopy for the Biological Sciences; 2-book Set
Gordon G. Hammes
Manufacturer: Wiley-Interscience
ProductGroup: Book
Binding: Paperback

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ASIN: 0471752142

Book Description

This title is a combination of Gordon G. Hammes' Thermodynamics and Kinetics for the Biological Sciences and Spectroscopy for the Biological Sciences.
* Includes the basic principles of thermodynamics, kinetics, and spectroscopy with a minimum of mathematics and applications to the biological sciences
* Exercises to assist in learning are presented at the end of each chapter
* Provides biology and biochemistry professionals a guide to understanding biophysical chemistry, with focus on thermodynamics, kinetics, and spectroscopy
* Coverage on spectroscopy in includes an introduction to fundamentals, electronic spectra, circular dichroism and optical rotary dispersion, vibration in macromolecules (IR, Raman, etc), magnetic resonance, X-ray crystallography, and mass spectrometry

Biophysical Thermodynamics of Intracellular Processes: Molecular Machines of the Living Cell

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Fundamentals of biophysics in the deepest

Biophysical Thermodynamics of Intracellular Processes: Molecular Machines of the Living Cell
Lev A. Blumenfeld , and Alexander N. Tikhonov
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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Book Description

The main goal of this book is to describe in physical terms the peculiar features of "machines" having molecular dimensions that play the principal role in the most important biological processes, viz., energy transduction and enzyme catalysis. Since these molecular engines work with thermal, chemical, and mechanical energy, the appropriate framework to discuss them comes from thermodynamics and chemical kinetics. The book thus begins with a review of the thermodynamics and chemical kinetics. It then discusses the notion of molecular machines, and in particular, the problems associated with applying thermodynamics to small systems such as enzymes. The authors then turn to enzyme catalysis, discussing theoretical and experimental investigations of protein dynamics. The concluding chapter deals with energy transduction in biological membranes, focusing on ATP synthesis.

Customer Reviews:

Fundamentals of biophysics in the deepest.......2000-03-29

This is one of the most thought provoking books on the fundamental issues of biophysics, including molecular machines, the relation between mechanics and statistics, and, ultimately, on the meaning of life itself. Everyone thinking deeply about basic biophysics should read it.

Book Description

Demonstrating how rock physics can be applied to predict reservoir parameters, such as lithologies and pore fluids, from seismically derived attributes, this volume provides an integrated methodology and practical tools for quantitative interpretation, uncertainty assessment, and characterization of subsurface reservoirs. Including problem sets and a case-study for which seismic and well-log data and Matlab codes are provided on the Internet (http://publishing.cambridge.org/resources/0521816017), the book is intended for students of petroleum geoscience as well as professionals in the field.

Book Description

"Nothing could be done. The thing was universal and beyond our human knowledge or control. It was death for young and old, for weak and strong, for rich and poor, without hope or possibility of escape."

Just returned from his famous adventure in the Lost World, the resourceful Professor George Challenger faces his greatest danger yet: Earth will pass through a belt of poisonous ether, and mankind might not survive. As the poison enters the atmosphere, terror and madness sweep the globe. Cities are wracked by riots, societies crumble, and soon all communication ceases. Professor Challenger and his friends, barricaded in a sealed room, can only watch their planet die.

The Poison Belt stands as one of Sir Arthur Conan Doyle's finest stories. A first-rate sequel to The Lost World, this novel continues the adventures of one of the most memorable characters in speculative fiction. Brilliant, witty, insufferable, and blessed with a booming voice and a huge black beard, Professor George Challenger is an eccentric and able champion of the human race.

Customer Reviews:

Doyle's contribution to "post-apocalyptic" literature!.......2007-09-14

While Professor George Edward Challenger, a short, stocky, hirsute bull of a man is physically the complete opposite of Doyle's more well known protagonist, Sherlock Holmes, the same cannot be said of his pomposity, arrogance and mental dexterity. In that regard, he could well have been Sherlock's and Mycroft's long lost sibling.

As a scientist of the first order, comfortable in his astute, complex analysis of "the blurring of Frauenhofer's lines in the spectra both of the planets and of the fixed stars," Challenger concluded there had been a fundamental change in the ether that would "involve the ultimate welfare of every man, woman, and child upon this planet." In fact, his private prognostications were that the end of the world was at hand and, on the basis of that certainty, he issued a peremptory summons to his friends and colleagues from the "lost world" expedition - young Edward Malone, the reporter for the Daily Gazette; Professor Summerlee, a fellow scientist; and Lord John Roxton, gentleman adventurer and sportsman - to join him and his beloved wife as witness to the world's final hours!

Having only recently completed Conan Doyle's "The Lost World", I expected "The Poison Belt" to be a garment cut of the same cloth - a swashbuckling Victorian adventure tale of the exploits of heroic men's men! Not even close ... instead Doyle served up an optimistic, post-apocalyptic tale of a world given a taste of Armageddon and an unexpected second chance. Doyle's philosophical musings, disclosed through the conversations of the last five people to remain on the face of a dying earth, touched upon such tender ideas as love and friendship in the face of death. While Doyle might not have recognized it by the more modern label, his musings even wandered into what a modern cosmological philosopher would label the "anthropic principle".

A modern reader of "The Poison Belt" will know that the notion of an all-encompassing ether in the universe has long since been debunked. But that single failing detracted not one whit from the quality of the story. That same modern reader, I expect, will also be unlikely to share Doyle's optimism regarding the world's reaction to a second chance at life. But, for myself, when I finished the story, I smiled and silently prayed that Doyle was right and I was wrong!

Enjoy!

Paul Weiss

Well written and quite exciting!.......2006-09-14

Professor Challenger is still throwing his bulk, and his vast intellect, around, making enemies and inevitably being proved right. And so, when reporter Ed Malone receives an emergency telegram from him, demanding that he bring oxygen at once, Malone hastens out and gets the oxygen! It seems that Challenger has learned that the Earth is moving towards a poisonous section of space, and has figured out a way that he can save a few members of the human race - the last people left on Earth.

Professor George Edward Challenger is the lesser known creation of Sherlock Holmes' creator, Arthur Conan Doyle (1859-1930). Unlike the cool and calculating Homes, Challenger is irascible, domineering and extremely outspoken. In short, he is a lot of fun to read. However, unlike Holmes, Professor Challenger never caught on and as such only five Challenger stories were ever written, and this was the second of the five (written in 1913).

Although more than a little dated, scientifically, I found this story to be well written and quite exciting. It reflects a world that is now gone, but is quite interesting to read about. If you like adventure stories, then you will like this one. Read this book, and learn about A.C. Doyle's other hero!

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