Adenovirus Methods and Protocols: Volume 2: Ad Proteins and RNA, Lifecycle and Host Interactions, and Phyologenetics (Methods in Molecular Medicine)

Book Description

Adenovirus Methods and Protocols, Second Edition, now in two volumes, is an essential resource for adenovirus (Ad) researchers beginning in the field, and an inspirational starting point for researchers looking to branch into new areas of Ad study. In addition to updating and expanding important chapters from the first edition, the authors have added new chapters that address innovative, exciting areas of emphasis in Ad research, including Ad vector construction and use, real-time PCR, use of new animal models, and methods for quantification of Ad virus or virus expression/interactions. Each of the protocols presented in these volumes is written by trendsetting researchers in their respective areas of expertise.

Volume 1 addresses several important techniques for construction of adenoviruses for use as vectors and for basic research. Highlighted topics include deletion mutants, capsid modifications, insertions, and gene replacements in human, murine, bovine, and ovine adenoviruses. In Volume 2, the authors focus on methods that elucidate and quantitate the interactions of Ad with the host. Each of the protocols in these volumes provides a general introduction, followed by tried-and-true step-by-step methods. Both novice and experienced researchers will reap tremendous benefit from these groundbreaking volumes in Ad research.

Macromolecular Crystallography Protocols, Volume 2: Structure Determination (Methods in Molecular Biology)

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Macromolecular Crystallography Protocols, Volume 2: Structure Determination (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 1588299023

Book Description

In the decade since publication of the first edition of Crystallographic Methods and Protocols the field has seen several major developments that have both accelerated the pace of structure determination and made crystallography accessible to a broader range of investigators. Volume I, Preparation and Crystallization of Macromolecules is dedicated to the crystallization and ways to increase the odds of obtaining crystals in macromolecules, while Volume 2, Structure Determination, covers both computational methods for characterizing crystals and solving structures.

Ion Channel Factsbook, Volume 2: Intracellular Ligand-Gated Channels (Factsbook)

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Ion Channel Factsbook, Volume 2: Intracellular Ligand-Gated Channels (Factsbook)

Manufacturer: Academic Press
ProductGroup: Book
Binding: Paperback

Biochemistry | Biological Sciences | Science | Subjects | Books

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ASIN: 012184451X

Book Description

How do you keep track of basic information on the proteins you work with? Where do you find details of their physicochemical properties, amino acid sequences, and gene organization? Are you tired of scanning review articles, primary papers and databases to locate that elusive fact?
The Academic Press FactsBook series will satisfy scientists and clinical researchers suffering from information overload. Each volume provides a catalogue of the essential properties of families of molecules. Gene organization, sequence information, physicochemical properties, and biological activity are presented using a common, easy to follow format. Taken together they compile everything you wanted to know about proteins but were too busy to look for.
In a set of four inter-related volumes, The ION Channel FactsBook provides a comprehensive framework of facts about channel molecules central to electrical signalling phenomena in living cells.
The second volume is devoted to Intracellular Ligand-Gated Channel Families including those molecular complexes activated or modulated by: Arachidonate and its metabolites, Inositol, phosphates, Ryanodine/Caffeine, Cyclic nucleotides, ATP binding and hydrolysis, Calcium ions, Sodium ions.

Key Features
* nomenclature
* expression
* sequence analyses
* structure and function
* electrophysiology
* pharmacology
* information retrieval

2D PAGE: Sample Preparation and Fractionation, Volume 1 (Methods in Molecular Biology)

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2D PAGE: Sample Preparation and Fractionation, Volume 1 (Methods in Molecular Biology)
Anton Posch
Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

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Book Description

This book presents a broad coverage of the principles and recent developments of sample preparation and fractionation tools in Expression Proteomics in general and for two-dimensional electrophoresis (2-DE) in particular. 2-DE, with its unique capacity to resolve thousands of proteins in a single run, is still a fundamental research tool for nearly all protein-related scientific projects. The methods described here in detail are not limited to 2-DE and can also be applied to other protein separation techniques.

2D PAGE: Sample Preparation and Fractionation, Volume 2 (Methods in Molecular Biology)

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2D PAGE: Sample Preparation and Fractionation, Volume 2 (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

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Book Description

3D QSAR in Drug Design: Volume 2: Ligand-Protein Interactions and Molecular Similarity (Three-Dimensional Quantitative Structure Activity Relationships)

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3D QSAR in Drug Design: Volume 2: Ligand-Protein Interactions and Molecular Similarity (Three-Dimensional Quantitative Structure Activity Relationships)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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Book Description

Volumes 2 and 3 of the 3D QSAR in Drug Design series aim to review the progress being made in CoMFA and other 3D QSAR approaches since the publication of the highly successful first volume about four years ago.
Volume 2 ( Ligand-Protein Interactions and Molecular Similarity) divides into three sections dealing with Ligand-Protein Interactions, Quantum Chemical Models and Molecular Dynamics Simulations, and Pharmacophore Modelling and Molecular Similarity, respectively.
Volume 3 ( Recent Advances) is also divided into three sections, namely 3D QSAR Methodology: CoMFA and Related Approaches, Receptor Models and Other 3D QSAR Approaches, and 3D QSAR Applications.
More than seventy distinguished scientists have contributed nearly forty reviews of their work and related research to these two volumes which are of outstanding quality and timeliness. These works present an up-to-date coverage of the latest developments in all fields of 3D QSAR.

Advances in Protein Chemistry - Volume 2

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Advances in Protein Chemistry - Volume 2
M. L. (ed) Anson
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover
ASIN: B000OYW3S4

Calcium-Binding Protein Protocols: Volume 2: Methods and Techniques (Methods in Molecular Biology)

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Calcium-Binding Protein Protocols: Volume 2: Methods and Techniques (Methods in Molecular Biology)

Manufacturer: Humana Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 0896036898

Book Description

Blurb for Volume 2

Hans Vogel and a panel of leading researchers review the protein chemistry and behavior of this significant class proteins, and provide a comprehensive collection of proven experimental techniques for studying it both in vitro and in vivo. This second volume focuses on cutting-edge experimental techniques for studying the solution structure, stability, dynamics, calcium-binding properties, and biological activity of calcium-binding protein in general. In addition to enzymatic assays and more routine spectroscopic and protein chemistry techniques, there are also NMR approaches, thermodynamic analyses, kinetic measurements such as surface plasmon resonance, strategies for amino acid sequence alignments, and fluorescence methods to study the distribution of calcium and calcium-binding proteins in cells. The first companion volume, Reviews and Case Histories sets the stage for this volume by introducing the various classes of intra- and extra-cellular calcium-binding proteins and their mode of action.

Single Blurb for Both Volumes

Hans Vogel and a panel of leading researchers review the protein chemistry and behavior of this significant protein class, and provide a comprehensive collection of proven experimental techniques for their study both in vitro and in vivo. The first volume discusses the role of calcium in intracellular secondary messenger activation mechanisms, including unique aspects of calcium chemistry and its utilization in dairy proteins and blood clotting. Detailed case studies provide a wealth of valuable information about protein purification and characterization strategies, X-ray crystallography, and specific calcium-binding proteins and their modes of action. The second volume focuses on cutting-edge experimental techniques for studying the solution structure, stability, dynamics, calcium-binding properties, and biological activity of calcium-binding protein in general. In addition to enzymatic assays and more routine spectroscopic and protein chemistry techniques, there are also NMR approaches, thermodynamic analyses, kinetic measurements such as surface plasmon resonance, strategies for amino acid sequence alignments, and fluorescence methods to study the distribution of calcium and calcium-binding proteins in cells.

Chemical Reagents for Protein Modification, Volume 2

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Chemical Reagents for Protein Modification, Volume 2
Roger L. Lundblad , and Claudia M. Noyes
Manufacturer: Crc Pr I Llc
ProductGroup: Book
Binding: Hardcover

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Comprehensive Biochemistry, Volume 8: Proteins (Part 2) and Nucleic Ac

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Comprehensive Biochemistry, Volume 8: Proteins (Part 2) and Nucleic Ac
Marcel Florkin
Manufacturer: see notes for publisher info
ProductGroup: Book
Binding: Hardcover
ASIN: B000M44YFQ

Book Description

Schad successfully leads students on an exploration of key physical concepts and their applications in the four disciplines of physical science. By repeatedly linking the fundamental discoveries and ideas of physics and their applications in other fields, the author helps students see the underlying simplicity and unity of nature, and presents a balanced coverage of topics. Schad writes conceptually and descriptively, introducing mathematical formula and sample problems (with answers) with discretion. Features include global surveys, boxes to introduce students to the frontiers of science, and original art and diagrams.

Theory of Macroscopic Systems: A Unified Approach for Engineers, Chemists and Physicists

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Theory of Macroscopic Systems: A Unified Approach for Engineers, Chemists and Physicists
Cor Ouwerkerk
Manufacturer: Springer
ProductGroup: Book
Binding: Paperback

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ASIN: 0387515755

A unified momentum equation approach for fluid-structure interaction (FSI) problems with stationary boundaries : (Dissertation)

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A unified momentum equation approach for fluid-structure interaction (FSI) problems with stationary boundaries : (Dissertation)
Jagadish Gattu
Manufacturer: ProQuest Information and Learning
ProductGroup: Book
Binding: Digital

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Unified frameworks for optimal production planning and scheduling: Continuous-time decomposition-based approaches: (Dissertation)

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Unified frameworks for optimal production planning and scheduling: Continuous-time decomposition-based approaches: (Dissertation)
Dan Wu
Manufacturer: ProQuest Information and Learning
ProductGroup: Book
Binding: Digital

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Book Description

Medea Georgievna Sinoply Mendez is an iconic figure in her Crimean village, the last remaining pureblooded Greek in a family that has lived on that coast for centuries. Looking like "a portrait Goya had omitted to paint" in the widow's black she has worn since the death of her husband–a jolly Jewish dentist–many years before, the childless Medea is the touchstone of a large family of nieces and nephews who, together with their spouses, children, and friends, gather each spring and summer at her home.

Ageless and unflappable, Medea greets each successive wave of visitors with calm warmth and welcome, and observes with interest their romantic entanglements, disappointments, conflicts, and passions. There are her nieces (the seductive and light-hearted Nike and the shy yet passionate Masha); her nephew Georgii (who shares Medea's devotion to the Crimea); and their friends, including Valerii Butonov, a circus performer turned sports trainer who has been pursued by women since he put on his first trousers. Herself unfailingly loyal and faithful, Medea watches her nieces and nephews fall in and out of marriages and affairs. These shifting currents of erotic attraction and competition intertwine with the dramatic saga of a family surviving the upheavals that characterized Soviet life in the twentieth century, as viewed through Medea's memories of the Russian Revolution and the two world wars, her parents' early deaths, and her own late marriage. Ludmila Ulitskaya, one of contemporary Russia's greatest novelists, weaves the stories of the sprawling Sinoply family into a brilliantly detailed and richly textured tapestry.

Customer Reviews:

A Real Book Again.......2005-03-11

I can't belive I am the first person to review this book. It was one of the best I have read in a long time and I read a lot of books. This book is all about the characters and their relationships to each other. It is also a great lesson in Soviet life through much of that period. If you want quick pacing or action this is not for you. If you want a story about people you actually care about this is for you.

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