Polymer Therapeutics I: Polymers as Drugs, Conjugates and Gene Delivery Systems (Advances in Polymer Science)

Book Description

Strategies to reduce medical uncertainty and build evidence have become critical to the advancement of medical knowledge and modern medical practice. As new techniques and strategies have arisen, so has the need for a current reference work. Drug Discovery and Design examines the latest research in the development of these new strategies. Some of the topics covered include angiotensin converting enzyme inhibitors, HIV protease inhibitors, PPAR agonists for diabetes, and glucan synthase antifungal agents.

3D QSAR in Drug Design: Volume 3: Recent Advances (Three-Dimensional Quantitative Structure Activity Relationships)

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3D QSAR in Drug Design: Volume 3: Recent Advances (Three-Dimensional Quantitative Structure Activity Relationships)

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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Book Description

Volumes 2 and 3 of the 3D QSAR in Drug Design series aim to review the progress being made in CoMFA and other 3D QSAR approaches since the publication of the highly successful first volume about four years ago.
Volume 2 ( Ligand-Protein Interactions and Molecular Similarity) divides into three sections dealing with Ligand-Protein Interactions, Quantum Chemical Models and Molecular Dynamics Simulations, and Pharmacophore Modelling and Molecular Similarity, respectively.
Volume 3 ( Recent Advances) is also divided into three sections, namely 3D QSAR Methodology: CoMFA and Related Approaches, Receptor Models and Other 3D QSAR Approaches, and 3D QSAR Applications.
More than seventy distinguished scientists have contributed nearly forty reviews of their work and related research to these two volumes which are of outstanding quality and timeliness. These works present an up-to-date coverage of the latest developments in all fields of 3D QSAR.

Advances in Blood Substitutes, Volume 3: Industrial Opportunities and Medical Challenges (Advances in Blood Substitutes, Vol 3)

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Advances in Blood Substitutes, Volume 3: Industrial Opportunities and Medical Challenges (Advances in Blood Substitutes, Vol 3)
R. Winslow
Manufacturer: Birkhäuser Boston
ProductGroup: Book
Binding: Hardcover

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ASIN: 0817639802

Book Description

The development of a substitute for transfused red blood cells is a highly sought-after goal. Such products potentially would be safer than human (allogeneic) blood because they would eliminate the possibility of transmitting infectious agents such as HIV. In addition, red cell substitutes will revolutionize the practice of transfusion medicine: they will eliminate the need for cross-matching, and could lead to an overhaul of current blood bank operations because they may be more stable and thus easier to store than blood. Before reaching this ambitious goal, the fundamental obstacle appears to be a lack of understanding of the way in which cell-free oxygen carriers transport oxygen, with consequent implications for clinical trials and eventual approval of new products. This volume is a collection of essays by outstanding authorities in a wide range of fields. Each chapter focuses on the problem of red cell substitutes from a different perspective. The discussion in the first chapter of the world-wide impact that blood substitute products would have is of particular interest and importance. All in all, this collection elucidates the current status of red cell substitute research and development in a unique and timely manner.

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Advances in Drug Discovery Techniques

Manufacturer: John Wiley and Sons Ltd
ProductGroup: Book
Binding: Hardcover

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ASIN: 0471975095

Book Description

This invaluable volume serves as a guide to up-to-the-minute techniques for the discovery and evaluation of pharmacologically active compounds for therapeutic development. Focusing on practical applications, provided by expert practitioners from both industry and academic research laboratories, Advances in Drug Discovery Techniques covers rational drug design, high-throughput screening and genetic approaches to drug discovery. Moreover, chapters also focus on advances in the use of combinatorial chemistry and natural products, both of which support the chemical diversity for many drug screening programmes. Typical screening studies and their link to robotics and informatics are also presented in detail, together with an overview of current progress within antisense therapeutics. Overall, this book will be an excellent reference source for all individuals interested in making sense of the rapid changes in drug discovery that result from developments in molecular biology, robotics and informatics.

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Advances in Drug Research

Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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ASIN: 012013330X

Book Description

This volume continues the trend for Advances in Drug Research of shorter, but more frequent volumes. In line with the tradition of the series, chapters on general themes are interspersed with chapters on specific drug classes and targets. It will be the last volume edited by Bernard Testa and Urs A. Meyer.

Advances in High Pressure Bioscience and Biotechnology II

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Advances in High Pressure Bioscience and Biotechnology II

Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 3540009779

Book Description

At present, there is growing interest in high pressure bioscience and biotechnology. The activities are nearly equally distributed between fundamental research and applications. With original work on marine and terrestrial microbiology, biochemistry, molecular biology, deep-sea diving, food science and other industrial applications, this book covers the whole range of current high pressure bioscience. Advances in High Pressure Bioscience and Biotechnology will be welcomed by all industrial and academic researchers who are working in this field.

Advances in Medicinal Chemistry, Volume 2 (Advances in Medicinal Chemistry)

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Advances in Medicinal Chemistry, Volume 2 (Advances in Medicinal Chemistry)

Manufacturer: Elsevier
ProductGroup: Book
Binding: Hardcover

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Book Description

Volume 2 of Advances in Medicinal Chemistry is comprised of six chapters on diverse facets of medicinal chemistry. Chapter 1 deals mainly addresses enzymological considerations and the rational design of novel steroid-based 5æ-reductase inhibitors, one of which (SKF-105657)is undergoing clinical evaluation. Chapter 2 relates to the discovery, structural elucidation, anti-tumor activity and DNA cleavage properties of the calicheamicins. This continues in Chapter 3 where the authors address CC-1065 as a potent anti-tumor antibiotic with an unusual structure. Chapter 4 gives an overview on the discovery at Merck of antagonists of cholecystokinin, a peptide hormone. In Chapter 5, an elaboration of a non-classic case of finding a nonpeptide small molecule for inhibition of a peptide receptor is given. Also addressed are the structure-activity relationships for a novel series of substituted imidazoles that antagonise the angiotensin II receptor. Finally, Chapter 6 chronicles the evolution of the aldose reductase inhibitor program at Pfizer, from sorbinil to zopolrestat.

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Advances in Pharmaceutical Sciences
H. S. Bean
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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Excellent

Paradigm of Observational Consciousness

A small book that tells a lot

Highly Recommended

Interesting, Complex, and Insightful

The Dimensional Structure of Consciousness: A Physical Basis for Immaterialism
Samuel Avery
Manufacturer: Compari
ProductGroup: Book
Binding: Paperback

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Transcendence of the Western Mind: Physics, Metaphysics, and Life on Earth

Mysticism and the New Physics (Arkana)

Unified Reality Theory: The Evolution of Existence into Experience

Quantum Enigma: Physics Encounters Consciousness

The Holographic Universe

ASIN: 0964629100

Book Description

The Dimensional Structure of Consciousness is a radical interpretation of modern physics. Rather than consciousness existing in space and time, it is suggested that the strange phenomena associated with quantum and relativity physics are better understood if space and time are structures within consciousness. Light is vision itself. Matter does not exist outside of consciosness. Mass is a second time dimension. This book is written for the educated layman as well as for the professional.

Customer Reviews:

Excellent.......2005-05-12

This book has pride of place on my shelf. As a neurochemist with 30 years experience in the sciences I have always been interested in consciousness and its relationship to reality. This book tackles this subject head on, and wins me over!

The book will not be easy reading for everyone. Those without a background in this area may find certain passages heavy going. Knowledge or physics is not assumed. However, without some background knowledge of the philosophy of the New Physics, some of the statements in this book have to be taken on faith. Still the book is about consciousness and how its dimensional structure is created, not theoretical physics.

The message in the book is simple and is one that has been stated in many other books. What distinguishes this book from many others is that it discards the usual waffle and mystic lingo and concentrates on a simple description of how consciousness evolves to create a dimensional view of reality. From this view comes our concept of space, time and matter... all products of awareness.

You may find this book difficult to understand if you have not read other books on the subject, or if you take conscious experience or reality at "face value". As a neurobiologist, I am well aware how the brain is able to build its own view of reality. Try reading some of the works of Douglas E. Harding first before reading this book, if you feel that would help. At any rate, the book is short, so there is little to be lost by reading it.

Every scientist should read this book. Reading it should make them ask the question, "what does it mean to discover some new scientific fact?"

Paradigm of Observational Consciousness.......2005-05-11

A very interesting book. Written by a layman and there are three quotes of recommendation by spiritual leaders on the back. This right away intrigued me, as it reminds me of other authors of physics who recognize the religious or spiritual nature of science. In this book, Avery relates how our senses appear as separate dimensions, dimensions that share the same area of consciousness or interactions with light infiltrating all in a different way in itself.

I found interesting is Avery's explanation of the quantum jump or leap to a far distance. In that it can only land at certain particular points, leaving a tunnel of space to question where this particle was traveling at what time? But only the locational points can be observed. What Avery does not point out is the idea I have read by David Bohm, and I'm sure a lot of others, that there may be no traveling at all, no tunnel, but a non-locality, a space-free, time-free dimension where the quantum jump, or illusionary jump, takes place.

The interesting thing here is the dimensions spoken of remind me of Rupert Sheldrake's morphic fields. Although there are large amounts of different fields, while the dimensions here spoken of are 6 and in addition, the is not about formative causation in morphic resonance. So is dimensions, touch, taste, sight, hear, think, and this observer consciousness, which Avery believes to be another dimension. "Trying to see or hear life is very much like a single cell trying to "feel" sound or light. Life in observers can be experienced only when experience is not limited to perception." p. 98. And then he finds that all of these 6 dimensions, to be recognized at once, have to all enter this "one" consciousness" to be shared by all of us, the collective. The paradox here is the collective in just one consciousness. Now it stands to reason, logically, that solipsism is the only logical answer. Solipsism is the belief that you, you reading this, is the only reality, real and only one consciousness, the rest are created by your mind and imagination. Your reality is only you . . no you, no reality, no consciousness.

With this problem of solipsism, Avery comes up with an interesting answer for his paradigm. It is that the collective, that is, all the people, are evolving, as in evolutionary growth, into a society that shares all of its information, creating a one schematic for information patterning, a one collective screen or perception (not a perceptional or subjective experience as much as a collective objective) to pattern and order the informational facts. In turn, this will be the answer to quantum interpretation of all consciousness as one.

"As human civilization evolves, direct perceptual experience becomes less a part of consciousness as a whole. We learn more about the world through other people, and observational experience becomes increasingly important. We talk, read books, watch moves, and gain information through electronic technology. We use the telephone, listen to radio, and watch the world on television. Observers become more important than objects. Experience through others becomes less distant; potential perception becomes a form of actual experience. You or I do not have to be there to experience what is happening in the world. We experience Asia, Africa, and the far side of the moon without ever perceiving it. Individual experience becomes more and more absorbed in collective experience, the perspective of actual perception is factored out along with that of potential perception. The quantum screen appears more and more like a point on a six-dimensional matrix. We each see ourselves individually as small parts of a greater collective whole." p100

"Western civilization has built an expanding universe within the human mind. The world of science is human imagination, carefully contained in an explosion of space and time, balanced by mass. Science creates what it discovers. At a small corner and to the side is the life process, a cross section of life itself. The great weakness in science is that it is contained at all and cannot see itself as such. it cannot go outside without getting cold." p. 104

A small book that tells a lot.......2004-10-26

This is a small book and it goes straight to the point - no beating around the bush. It will help you to grasp the process of thoughts transforming into material reality and the fact that the only difference between a thought and a tangible thing is a difference in vibration (dimension).

If you only read through the book, all that you will have left is a little bit more of intellectual understanding - but don't stop there. Armed with understanding about the fact that your thoughts influence the energy, which expresses as matter, create your own experiments, use your mind to intend specific outcomes and create the experiences in your life you'd like to have.

The understanding from this book will open new doors for you, making you aware of the fact that some things which might have seemed impossible before are possible, if you invest your thoughts to create them.

Highly Recommended.......2004-10-26

The essence of the book revolves around the idea that was part of all inner teachings of spiritual traditions and is now part of the quantum physics - that the universe is composed out of intelligent energy, and that therefore physical reality is also composed out of energy, which appears solid to physical senses only because our senses register particular vibrations as solid. From this worldview, a thought of a table is just as real as the table - the only difference is that they vibrate at different frequencies and are thus said to exist in different dimensions.

Interesting, Complex, and Insightful.......2003-11-25

I found this book incredibly interesting...as well as linguistically arduous. Avery has a daedal idea of consciousness and dimensionality. His unique views have definitely impacted my hardcore empirical, materialistic philosophy persona. I highly recommend this book to those who are well read in the subject already and semantically sound.

Though I did not understand his entire argument (and will undoubtedly have to read it again and again to reach some sort of "complete" understanding), I found this read worth every second I gave it! My only complaints would be his lack of clarity at times...it was difficult to visualize his argument, but with effort, is possible.

...Awesome, awesome ideas...wow

Book Description

This new selection of Dickens's Christmas writings confirms his lasting influence upon our idea of the Christmas spirit: that Christmas is a time for celebration, charity, and memory. In addition to the beloved A Christmas Carol, this volume includes such festive works as "Christmas Festivities," "The Story of the Goblins Who Stole a Sexton," "A Christmas Tree," "The Seven Poor Travellers," The Haunted Man and the Ghost's Bargain, and a Christmas episode from Master Humphrey's Clock.

Customer Reviews:

Stories That Will Warm Cold Winter Nights.......2006-02-20

CHARLES DICKENS A CHRISTMAS CAROL AND OTHER CHRISTMAS WRITINGS is a wonderful collection of Christmas renderings previously published in various Charles Dickens collections. Always the holiday favorite during the Christmas season, old Ebenezer Scrooge and his cast of spirits set the stage for A CHRISTMAS CAROL, which is the highlight of the book. However, the other stories included in this volume are a delight to read and show blueprints to the CAROL as well as after thoughts, such as 'The Story of the Goblins who Stole a Sexton' and THE HAUNTED MAN AND THE GHOST'S BARGAIN.

Beyond the holly and the ivy, Charles Dickens' writings show readers his references to societal issues in nineteenth century England that revolve around Christmas. Dickens explores issues, which relate to class and memory in order to achieve deeper meaning and human qualities for the characters he creates. In an era where industry and consumption began to overtake the true meaning of Christmas, Dickens uses his craft to show readers to compassion still exists during hard times. The latter stories in the book exemplify his intentions, "A Christmas Tree", "What Christmas Is, As We Grow Older", and "The Seven Poor Travellers."

Dickens charming stories have a timeless quality that have been revered through time regardless of what century or season they have been read. For those already familiar with the Carol, the other stories will offer more insight to Dickens' writings. Overall, this is a great collection that may be read like campfire stories on a cold winter's night, or simply cozily by the fireplace.

The Birds' Christmas carol: The story of Patsy, Timothy's quest, and other stories (The writings of Kate Douglas Wiggin)

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The Birds' Christmas carol: The story of Patsy, Timothy's quest, and other stories (The writings of Kate Douglas Wiggin)
Kate Douglas Smith Wiggin
Manufacturer: Houghton, Mifflin
ProductGroup: Book
Binding: Unknown Binding

Contemporary | General | Literature & Fiction | Subjects | Books

A Christmas Carol and Other Christmas Writings.(Book Review): An article from: Reviewer's Bookwatch

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A Christmas Carol and Other Christmas Writings.(Book Review): An article from: Reviewer's Bookwatch
Pete Hodgins
Manufacturer: Midwest Book Review
ProductGroup: Book
Binding: Digital

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Book Description

This digital document is an article from Reviewer's Bookwatch, published by Midwest Book Review on January 1, 2005. The length of the article is 618 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: A Christmas Carol and Other Christmas Writings.(Book Review)
Author: Pete Hodgins
Publication: Reviewer's Bookwatch (Newsletter)
Date: January 1, 2005
Publisher: Midwest Book Review
Page: NA

Article Type: Book Review

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A Christmas Carol and Other Christmas Writings (Penguin Classics)

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A Christmas Carol and Other Christmas Writings (Penguin Classics)
Michael Slater Charles Dickens
Manufacturer: Penguin Classics
ProductGroup: Book
Binding: Paperback

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