Cellular Ageing PT. 2: Concepts and Mechanisms: Mechanisms II: Translation, Transcription and Structural Properties (Interdisciplinary Topics in Gerontology)

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Mechanisms in Transcriptional Regulation provides a concise discussion of the fundamental concepts in transcription and its regulation. Beginning with an overview of RNA polymerases and the general transcriptional machinery, this book goes on to cover the mechanisms of transcriptional activation, the histone code hypothesis, the epigenetic control of transcription, and combinatorial control in signaling and development.Mechanisms in Transcriptional Regulation contains many features designed to aid understanding. More than 80 figures crystallize and amplify the ideas presented in the text. Boxes set off from the main text offer background information on important theoretical concepts and experimental methods. Thought-provoking problems test students ' understanding of key concepts. Extensive reading lists included in each chapter provide guidance for further studies. In addition, the book is accompanied by a dedicated website that includes all the art from the book in downloadable format. These features make this text an ideal resource for upper-level undergraduate, graduate and postgraduate students alike.

Mechanisms of DNA Damage Recognition in Mammalian Cells (Molecular biology intelligence unit)

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Mechanisms of DNA Damage Recognition in Mammalian Cells (Molecular biology intelligence unit)
Hanspeter Naegeli
Manufacturer: R G Landes Co
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Binding: Hardcover

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ASIN: 1570594384

Mechanisms of Transcription (Cold Spring Harbor Symposia on Quantitative Biology)

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Mechanisms of Transcription (Cold Spring Harbor Symposia on Quantitative Biology)
Cold Spring Harbor Laboratory
Manufacturer: Cold Spring Harbor Laboratory Press
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Binding: Hardcover

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Mechanisms of Transcription (Nucleic Acids and Molecular Biology, Vol. 11)

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Mechanisms of Transcription (Nucleic Acids and Molecular Biology, Vol. 11)

Manufacturer: Springer-Verlag Telos
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Binding: Hardcover

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Mechanisms of Transcription presents a unique perspective on the fundamental processes of transcription. A collection of distinguished authors draws together the underlying mechanisms involved in the process of transcription. This includes RNA polymerase function and its interaction with promoter sequences, and the structures of the various components on the transcriptional machinery. Both prokaryotic and eukaryotic systems, NMR and crystallographic structures of a number of important eukaryotic transcription factors are discussed, as well as the role of chromatin structure.

Mechanisms of Transcription: Cold Spring Harbor Symposia on Quantitative Biology (CSH Symposia on Quantitative Biology) (CSH Symposia on Quantitative Biology)

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Mechanisms of Transcription: Cold Spring Harbor Symposia on Quantitative Biology (CSH Symposia on Quantitative Biology) (CSH Symposia on Quantitative Biology)

Manufacturer: Cold Spring Harbor Laboratory Press
ProductGroup: Book
Binding: Paperback

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Oncogenes As Transcriptional Regulators (Progress in Gene Expression)

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Oncogenes As Transcriptional Regulators (Progress in Gene Expression)

Manufacturer: Birkhauser
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Binding: Hardcover

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ASIN: 0817657096

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Two volume set. Please see: Vol I: ISBN:3-7643-5486-0 & Vol II: ISBN 3-7643-5709-6

Transcription: Mechanisms and Regulation (Raven Press Series on Molecular and Cellular Biology)

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Transcription: Mechanisms and Regulation (Raven Press Series on Molecular and Cellular Biology)
Ronald C. Conaway
Manufacturer: Raven Pr
ProductGroup: Book
Binding: Hardcover

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This volume provides an up-to-date account of recent research on the basic transcriptional regulatory mechanisms that govern gene expression. Leading international experts present concise yet thorough reviews of a large number of very productive lines of research, with particular emphasis on biochemical investigations of the structures and mechanisms of action of bacterial, viral, and eukaryotic RNA polymerases and the transcription factors that control their activities throughout the transcription cycle.

Transcriptional control mechanisms: Proceedings of a Cetus-UCLA symposium held in Keystone, Colorado, April 6-13, 1986 (UCLA symposia on molecular and cellular biology)

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Transcriptional control mechanisms: Proceedings of a Cetus-UCLA symposium held in Keystone, Colorado, April 6-13, 1986 (UCLA symposia on molecular and cellular biology)

Manufacturer: A.R. Liss
ProductGroup: Book
Binding: Unknown Binding

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ASIN: 0845126512

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Comprehensive and up-to-date, this unique four-volume set offers readers a complete overview of the broad spectrum of general chemistry. It enables them to obtain a basic, yet thorough understanding of matter, the processes it undergoes, the principles that govern it, and the international cast of men and women who have been critical in the development of the science of chemistry. From elements, atoms, and molecules to sterochemistry, spectroscopy, and chemical bonding, its clear and concise explanations provide an illuminating and readily comprehensible introduction. Key presentations include forty element definition articles, each providing basic periodic table information and general information on the element in question. Ninety-five biographical articles deal with prominent chemists, while other articles provide additional historical context, particularly with respect to eighteenth-, nineteenth-, and twentieth-century developments. Four volumes

Macmillan Encyclopedia of Chemistry, 4 vols

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Macmillan Encyclopedia of Chemistry, 4 vols

Manufacturer: Macmillan, New York
ProductGroup: Book
Binding: Hardcover
ASIN: B000I9EQJO

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In this book I have tried to tell something of the life of Erwin Schrodinger in such a way that even those who are not scientists may be able to understand the greatness of his work, the range of his ideas, and the kind of person he was.

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All aspects of Schrödinger covered.......2005-12-26

Walter Moore captures the life of Erwin Schrödinger, one of the most important theoretical physicists of the 20th century, covering his career, science, philosophy and personal life.

In this ambitious book Moore tries to shed light on all aspects of Schrödinger's life, and tries to connect them, but no coherent picture evolves. I had the impression, however, that this is not Moore's fault, but that the pieces that made up Erwin Schrödinger did not fit into a coherent whole.

A gifted student from an early age on, he took on physics. After initially dwelling in different sub-fields, he developed wave mechanics at the (for creative work in theoretical physics) late age of 38. His almost unparalelled mathematical skills made this advance possible. Schrödinger never saw mathematics only as a tool, but he greatly appreciated it's beauty. Moore does an excellent job in describing the intellectual journey towards this discovery, as well as the giants on who's shoulders Schrödinger was standing. For this work Schrödinger received the Nobel prize in 1933.

In his later years, he dedicated a substantial part of his efforts to the search for a unified (quantum mechanics - relativity) theory of physics. Just like Einstein, with whom he had an extensive correspondence about the mater, he failed. Schrödinger's scientific work is explained in quite a bit of detail. Despite being quite familiar with differential equations, but without a background in theoretical physics, I must admit that I had a hard time following Schrödinger's insights as presented by Moore.

From his student days on, Erwin Schrödinger was a believer in the Indian teachings of Vedanta, proclaiming a one-ness of all minds, which make up reality. It is hard to see how a rational 20th century scientist could adhere so uncritically to an ancient religion. However, these beliefs seemingly did not influence his science much and neither did they influence his personal life.

His personal life was, nevertheless, unusual. He was a lover of interesting women, and he had many (I am all for that!), but many of his loves were still teenagers, while he was in his 30s and 40s (very weired!). For a man of such high intellectual capacity, this shows very poor moral judgment. He was not solely interested in sex, but sincerely in love with many of them and wrote them love poems.

Schrödinger also showed somewhat poor moral judgment in terms of politics, although the turmoils of the 20th century greatly affected him (he was removed from his professorship in Graz by the Nazis). He was not an opportunist, like so many of his fellow Austrian and German physicists. Although he leaned to the left, he basically was not interested in politics at all. An irresponsible neglect during the rise of fascism in Europe!

Moore brings together all these aspects of Erwin Schrödinger, and he does so with lots of knowledge of the local culture and history of the places Schrödinger visited and lived at (Vienna, Graz, Dublin, Cambridge). This is a well researched book in all aspects and one with lots of sympathy for "Erwin".

Scientific and sexual fireworks........2003-06-20

This is a masterful biography, but one need to have a profound knowledge of higher mathematics and a basic one in physics to fully understand it.

Walter Moore shows that Schrödinger's life and thought was at least controversial.

Life
Schrödinger's personal itinerary is exemplary for the 20th century. He was born in a comfortable upper-middle class, but his parents lost their savings in the German inflation after WW I. The result was famine and diseases. It marked the rest of his life. As a young man he was confronted with unemployment and nearly left physics for financial reasons!
He found a decent job only at the age of 34. Even after winning the Nobel Prize he was still confronted with 'pension' problems.

Science
Walter Moore gives us a magisterial and detailed analysis of the scientific discoveries of ES, from his humble beginnings to the elaboration of the quantum wave function and after.
It shows that ES was above all a mathematical genius and a not so brilliant experimenter.
ES remained all his life opposed to the complemantary (particle/wave) interpretation of quantum mechanics (the 'Kopenhagen oracle' for ES). For him, there were only waves!

Sex
Beside science, sex was the principal occupation of his life, with all combinations imaginable. He lived a ménage à trois and sometimes à quatre, but still fell in love with other women, also with very young ones for he had a Lolita complex. He could without doubt have been accused of paedophilia.
But his intense love affairs stimulated highly his scientific creativity.
One can only wonder if his 'wild' behaviour and negative view of bourgeois marriage were not fundamentally influenced by the fact that he couldn't marry his first true love, because her family found that he was too poor!

Politics
He had a deep contempt for the governing classes (politicians, clergy) who 'enslave men by violence and use the religious desire of many people to promote superstition to rule over the dispossessed'. He also distrusted democracy!

Philosophical world view
This is certainly one of the strangest aspects of his thoughts.
He was convinced that physics provided absolutely no answers to philosophical questions (e. g. free will). All his life he remained, like Einstein, an adept of determinism.
His philosophical views and ethical principles were completely dissociated from his real life!
As an adept of the Vedanta, he believed the Buddhist wisdom that a thing could be both A and non-A (horribile dictu)!
He was also heavily influenced by the philosophy of Schopenhauer.

This work gives excellent explanations of the Vedanta, and the philosophy of Mach and Schopenhauer.
It contains a very painful paragraph on Heidegger.

I see only one minus point: the author doesn't give Bohr's pertinent response to the EPR-article against the Copenhagen interpretation of qm.

This is a brilliant book and certainly the definitive biography of Schrödinger. It is by no means a hagiography and doesn't dodge some 'weird' aspects of Schrödinger's life.
Not to be missed.

....WOW.......2002-03-17

This book, is amazing. I came across it because I was forced to do a project for chemistry on Erwin Schrödinger, and I'm glad I did. It's a 512 page biography of him, and I think that says it all. It covers and extensive amount of ground, and is very useful for anyone doing any researh on the man. It gives a lot of background information about what was going on in his life, and the events in the world around him. Whenever he went to a new college, there was always some information on the college itself. If Schrödinger did research on a topic, there would be a small history on the scientist that came before him and how they affected him. The book is virtually packed with quotes form other people, letters, and speeches. One of the other things I liked was that it contained details of Schrödinger's personal life, such as his extramarital affairs and details on his marriage, and his family history. Want to see some pictures? There's that too. Bet you didn't know that Schrödinger wrote poetry. Well he did, and all of it is here too, in both German and an English translation. Another thing that makes the book stand out it that it is bery readable. Walter Moore did an excellent job writing the book, and it shows. I can say that you only need to read one book about Schrödinger: this one.

I tawt I taw a putty tat!.......2001-02-16

The 20th century has boasted a greater number of top-notch physicists than any prior epoch in history. The 21st century, and any future century beyond it, will be hard-pressed to match the level of scientific genius presented by the 20th. Names such as John Archibald Wheeler, Eugene Wigner, Paul Dirac, Max Planck, Louis deBroglie, Werner Heisenberg, Niels Bohr, Albert Einstein, Wolfgang Pauli, John von Neumann, Richard Feynman, Roger Penrose, Freeman Dyson and Stephen Hawking have set the standard for scientific and intellectual excellence.

Another name which belongs in this esteemed list is that of Erwin Schroedinger. Schroedinger influenced the field of quantum mechanics perhaps more than any other single scientific contributor of modern times. Here, Walter Moore has compiled his unique story so that all may have access to the life and times of this extraordinary man.

Moore's writing style is easily up to the task of keeping the interest of the reader. He does an excellent job of tracing Schroedinger's academic career as he obtained posts at the university of Jena, university of Zurich, university of Berlin [he was the hand-picked successor of none other than Max Planck], university of Oxford, university of Graz (Austria), the Dublin Institute for Advanced Studies and the university of Vienna. Schroedinger was also offered professorships at 2 US universities as well (university of Wisconsin, Madison and Princeton university), but declined both. Moore does an exquisite job in his disinterment of all the facts, personal factors and politics behind S' decisions to transfer (or not to transfer) from post to post. Moore's elucidation of S' relationship with the Nazis (who called him "Politically unreliable") is exemplery, as is his coverage of the friendships and correspondence that S shared with his peers.

What makes Moore's biography superb is that he equally concentrates on S' personal life as well as his intellectual endeavors. Moore gives an authentic and upfront treatment of S' rather bizarre love arrangements. Like the composer Richard Wagner, S had many affairs with the wives of his friends (a few of which resulted in children), as well as myriad young woman just reaching adulthood. Moore offers a credible psycho-analysis of the motivations for his sexual conquests, and comparisons to the behavior of the persona in Nabokov's "Lolita" which Moore alludes to are certainly warranted.

Like all good modern biographies, the book is filled with plenty of pictures of the personages and locales which were integrated within S' life [including the immortal assemblage of the 1927 (5th) Solvay conference]. Also, for the mathematically inclined amongst us, the work is filled with a good many of the equations that S developed and worked on during his lifetime. The good news, for those of us not so mathematically inclined, is that an understanding of them is not essential to a generic comprehension of what S accomplished.

I cannot recommend this book highly enough for all fans of and admirers of this great individual. People who have an interest in the history of science, physics in the 20th century, the philosophy of science and the psychology of the genius will also gain a great deal by reading this biographical treatise. Einstein once wrote S that "...you are my closest brother and your brain runs so similarly to mine" (p 426). This is a splendid illustration of just how pivotal he was to the history of science. In this biography, Moore set out to tell his story. HE DID!! HE DID!!

Book Description

ALEJANDRO DUMAS
EL CONDE DE MONTECRISTO
LEÍDO POR: GUILLERMO PIEDRAHITA
La venganza era su única diosa

Entre las novelas de aventuras de Alejandro Dumas, siempre ha ocupado lugar preferencial la historia de Edmundo Dantés, quien condenado injustamente a morir en la prisión de If, logra escapar, encontrar un tesoro y bajo la personalidad ficticia de Conde de Montecristo, dedica el resto de su vida a vengarse implacablemente de quienes lo llevaron al encarcelamiento, pero también a beneficiar a todos aquellos que lo ayudaron y tuvieron un gesto de bondad en el momento de necesidad. Ese personaje lleno de contradicciones y que sabe premiar a los buenos y castigar a los malos es uno de los más legendarios en toda la literatura de aventuras y la genial creación de Dumas siempre ha sido una de las preferidas del público. Es obra que nunca ha dejado de ser editada y se ofrece con orgullo dentro de esta colección. REF: 70064 cassette 80064COD. ISBN CD: 958-9494-79-X COD. ISBN CT: 958-43-0065-2

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El Conde de Monte Cristo.......2004-01-19

El Conde de Monte Cristo me trae muchos recuerdos maravillosos. Lo lei en 1973, durante un tiempo que estuve con muchos problemas y este libro fue mi escape. Me ayudo a seguir siendo valiente para seguir adelante. En 2003, le comente a mi nieto de 12 anos sobre este libro y tambien lo leyo, y le parecio estupendo.

The Count of Monte Cristo, 1944. Kniga 2 (IN RUSSIAN LANGUAGE) / Graf Monte-Kristo. V 2kn. Kn. 2 / Der Graf von Monte Christo / El conde de Montecristo /

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The Count of Monte Cristo, 1944. Kniga 2 (IN RUSSIAN LANGUAGE) / Graf Monte-Kristo. V 2kn. Kn. 2 / Der Graf von Monte Christo / El conde de Montecristo /
Alexandre dumas , Dumas Davy de la Pailleterie , and père Alexandre Dumas
Manufacturer: AST
ProductGroup: Book
Binding: Hardcover

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ASIN: 5170078935

Conde de Montecristo (Count of Monte Cristo)

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Conde de Montecristo (Count of Monte Cristo)
Alejandro Dumas
Manufacturer: Turtleback Books Distributed by Demco Media
ProductGroup: Book
Binding: Unknown Binding

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El Conde de Montecristo / The Count of Monte Cristo (Biblioteca Escolar/ School Library)

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El Conde de Montecristo / The Count of Monte Cristo (Biblioteca Escolar/ School Library)
Alexandre Dumas
Manufacturer: Grijalbo Mondadori Sa
ProductGroup: Book
Binding: Paperback

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