Rho GTPases (Molecular Biology Intelligence Unit)

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Members of the Rho family of small GTP-binding proteins (GTPases) are key signal transduction proteins that mediate signals initiated by growth factors, cytokines and cell adhesion proteins. Our knowledge about Rho GTPases has rapidly expanded over the past several years and Rho GTPases is the first book to provide a comprehensive overview of the regulation and functions of this important class of proteins.
This book includes several chapters dedicated to the review of various classes of proteins that control the localization and activation state of Rho GTPases. Additional chapters discuss the wide range of biological functions that are controlled by Rho GTPases, including the organization of the actin cytoskeleton, cell proliferation and cell motility.
Rho GTPases is essential reading for cell and molecular biologists, biochemists and geneticists. The critical roles of Rho family members in cancer and inflammatory diseases makes Rho GTPases also an invaluable guide for clinical investigators and pharmacologists.

Regulators and Effectors of Small GTPases, Part D: Rho Family (Methods in Enzymology, Volume 325) (Methods in Enzymology)

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Regulators and Effectors of Small GTPases, Part D: Rho Family (Methods in Enzymology, Volume 325) (Methods in Enzymology)

Manufacturer: Academic Press
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Binding: Hardcover

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ASIN: 0121822265

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This volume and its companions ( Volumes 255, 256, 257, and the forthcoming 329) cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level.
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Bacterial Virulence Factors and Rho GTPases (Current Topics in Microbiology and Immunology)

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Bacterial Virulence Factors and Rho GTPases (Current Topics in Microbiology and Immunology)

Manufacturer: Springer
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Binding: Hardcover

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ASIN: 3540238654

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Pathogenic bacteria for human and animals have developed sophisticated weapons, termed virulence factors, to ensure their replication and persistence into their hosts. The authors in this volume show a synthesis on how the various host cellular Rho GTPases activities are manipulated by bacteria to fulfil their virulence.

Characterization of Rho GTPases during wound healing : (Dissertation)

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Characterization of Rho GTPases during wound healing : (Dissertation)
Helene Anne Benink
Manufacturer: ProQuest Information and Learning
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Binding: Digital

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Identification of Rho family GTPases in porcine sperm and their role in the acrosome reaction: Initial characterization of a Rho-mediated pathway : (Dissertation)

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Identification of Rho family GTPases in porcine sperm and their role in the acrosome reaction: Initial characterization of a Rho-mediated pathway : (Dissertation)
Clarence Carl, III Ducummon
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Binding: Digital

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Methods in Enzymology, Volume 406: Regulators and Effectors of Small GTPases: Rho Family

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Methods in Enzymology, Volume 406: Regulators and Effectors of Small GTPases: Rho Family

Manufacturer: Academic Press
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ASIN: 0121828115

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The Ras superfamily (>150 human members) encompasses Ras GTPases involved in cell proliferation, Rho GTPases involved in regulating the cytoskeleton, Rab GTPases involved in membrane targeting/fusion and a group of GTPases including Sar1, Arf, Arl and dynamin involved in vesicle budding/fission. These GTPases act as molecular switches and their activities are controlled by a large number of regulatory molecules that affect either GTP loading (guanine nucleotide exchange factors or GEFs) or GTP hydrolysis (GTPase activating proteins or GAPs). In their active state, they interact with a continually increasing, functionally complex array of downstream effectors.

Since the last Methods in Enzymology volume on this topic in 2000, Rho GTPases have continued to receive a huge amount of attention. The human genome sequence has revealed the full extent of the Rho GEF and Rho GAP families (over 80 members for each) and the challenge of identifying the molecular interactions and cellular pathways influenced by each of these regulators is a daunting prospect. This new volume describes some of the methods currently being used to examine Rho family GTPase regulation at the biochemical and cellular level.

*Describes the methods currently being used to examine Rho family GTPase regulation at the biochemical and cellular levels.
*Includes new imaging techniques that revolutionize the ability to visualize GTPase activities.
*Over 150 international contributors.

Rho Family GTPases (Proteins and Cell Regulation)

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Rho Family GTPases (Proteins and Cell Regulation)

Manufacturer: Springer
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Binding: Hardcover

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ASIN: 140203461X

Book Description

This volume provides a unique collection of detailed chapters from some of the leading research groups in the world, many of which have made key discoveries in the field. This allows for particularly insightful discussion of the current understanding of Rho function.

Work on signal transduction pathways involving Rho family GTPases started some ten years ago. There is now a realization that these highly conserved molecular switches not only serve to coordinate cytoskeletal organization but also impact on diverse aspects of cell biology such as membrane trafficking, transcriptional regulation and mitotic progression.

Humans contain more than 20 Rho type GTPases. This volume not only presents a detailed phylogenetic analysis of Rho proteins, but also discusses the possible origins of the human members. Such an analysis of human Rho GTPases has not previously been attempted.

The book includes an overview of how Rho GTPases become activated which is complemented by an extensive Chapter by Darerca Owen and Helen Mott who unravel the beautiful molecular details given to us by the many structural studies of Rho GTPases.

The key areas currently being investigated in relation to these ubiquitous proteins are described for both in vitro and in vivo systems. These are presented in a format that ensures the reader can approach the topic with minimal background knowledge, while ultimately bringing the subject to the level of an expert. Timely and highly authoritative, this volume illuminates newer findings, particularly as they relate to Rho proteins in vertebrate biology.

Small Gtpases & Their Regulators, Part B: RHO Family (Methods in Enzymology)

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Small Gtpases & Their Regulators, Part B: RHO Family (Methods in Enzymology)

Manufacturer: Academic Press
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Binding: Hardcover

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ASIN: 0121821579

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General Description of the Volume:
Small GTPases play a key role in many aspects of contemporary cell biology: control of cell growth and differentiation; regulation of cell adhesion and cell movement; the organization of the actin cytoskeleton; and the regulation of intracellular vesicular transport. This volume plus its companion Volumes 255 and 257 cover all biochemical and biological assays currently in use for analyzing the role of small GTPases in these aspects of cell biology at the molecular level. It is the first compendium of practical techniques for working with small GTPases of the Rho group.
General Description of the Series:
The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

The Rho GTPase guanine nucleotide exchange factor Vav3 enhances androgen receptor transcriptional activity through ligand-dependent and independent mechanisms: (Dissertation)

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The Rho GTPase guanine nucleotide exchange factor Vav3 enhances androgen receptor transcriptional activity through ligand-dependent and independent mechanisms: (Dissertation)
Leah Lyons
Manufacturer: ProQuest Information and Learning
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Binding: Digital

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Rho GTPases in the development and maintenance of neuronal morphology: (Dissertation)

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Rho GTPases in the development and maintenance of neuronal morphology: (Dissertation)
Ann Yukari Nakayama Goldstein
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Weakly Nonlocal Solitary Waves and Beyond-All-Orders Asymptotics: Generalized Solitons and Hyperasymptotic Perturbation Theory represents the first thorough examination of weakly nonlocal solitary waves, which are just as important in applications as their classical counterparts. The book describes a class of waves which radiate away from the core of the disturbance but are nevertheless very long-lived nonlinear disturbances. Specific examples are provided in the areas of water waves, particle physics, meteorology, oceanography, fiber optics pulses and dynamical systems theory. For many species of nonlocal solitary waves the radiation is exponentially small in 1/epsilon where epsilon is a perturbation parameter, thus lying `beyond-all-orders'. A second theme is the description of hyperasymptotic perturbation theory and other extensions of standard perturbation methods. These methods have been developed for the computation of exponentially small corrections to asymptotic series. A third theme involves the use of Chebyshev and Fourier numerical methods to compute solitary waves. Special emphasis is given to steadily-translating coherent structures, a difficult numerical problem even today. A fourth theme is the description of a large number of non-soliton problems in quantum physics, hydrodynamics, instability theory and others where `beyond-all-order' corrections arise and where the perturbative and numerical methods described earlier are essential. Later chapters provide a thorough examination of matched asymptotic expansions in the complex plane, the small denominator problem in Poincaré-Linstead (`Stokes') expansions, multiple scale expansions in powers of the hyperbolic secant and tangent functions and hyperasymptotic perturbation theory. This book will be of special interest to applied mathematicians, fluid dynamicists in mechanical and aeronautical engineering, electrical engineers interested in fiber optics, quantum chemists and atomic and particle physicists.

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Excellent book.......2000-06-23

Authored by an expert applied mathematician in atmospheric and oceanic fluid physics, the book is an excellent source for researchers in this field.

Book Description

fiction, ed w/intro by Douglas Messerli

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Strange, Beautiful Smoke.......2001-04-09

If my memory serves me well, I first learned of "Smoke and Other Early Stories" after reading an article about Douglas Messerli, founder of Sun & Moon Press in Los Angeles. Messerli spoke of his giddy discovery that the copyright on many of Barnes' short stories had run so he had the legal right to publish them. Though Barnes apparently was not pleased by this, this collection is the result. And God bless the result. These fourteen tales (puntuated by Barne's own strange and evocative pen-and-ink illustrations) should be read by anyone who loves well-crafted, provative short fiction; and it should be a must for those who are beginning writers. The first sentence of each story introduces you to a world where everyday people and things transmute inexplicably into something weird and dreamlike: "Every Saturday, just as soon as she had slipped her manila pay envelope down her neck, had done up her handkerchiefs and watered the geraniums, Paprika Johnson climbed onto the fire-escape and reached across the strings of her pawnshop banjo." (From "Paprika Johnson.") Sometimes, she sets the stage simply as with the first line of "What Do You See, Madam?": "Mamie Saloam was a dancer." As Messerli notes in the introduction, Barnes' stories were published in newspapers at a time (the first two decades of the 1900s) when the public expected to see short fiction in such venues. Reading this collection can only make you long for such an era.

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Smoke and Other Early Stories.
Djuna. BARNES
Manufacturer: Los Angeles: Sun & Moon,
ProductGroup: Book
Binding: Paperback
ASIN: B000U929KU

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Smoke and Other Early Stories
Djuna Barnes
Manufacturer: Sun & Moon Press
ProductGroup: Book
Binding: Hardcover
ASIN: B000J40O9Y

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Smoke and Other Early Stories
Djuna; Messerli, Douglas (editor) Barnes
Manufacturer: Cannon Book Distribution, Limited
ProductGroup: Book
Binding: Paperback
ASIN: B000KXALWY

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Smoke and Other Early Stories

Manufacturer: Sun & Moon Press
ProductGroup: Book
Binding: Paperback

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