Adenoviral Vectors for Gene Therapy

Book Description

Adenoviral Vectors for Gene Therapy provides detailed and comprehensive coverage of these important therapeutic agents. The topics covered in this book range from the basic biology of adenoviruses, through the construction and purification of adenoviral vectors, cutting-edge vectorology and the use of adenoviral vectors in preclinical animal models, to regulatory issues which must be considered prior to the initiation of human clinical gene therapy trials. The broad scope of this unique volume provides the reader with a complete understanding of the development and use of adenoviral vectors.

Key Features
* Provides complete coverage of basic biology of adenoviruses, as well as the construction, propagation and purification of adenoviral vectors
* Introduces common strategies for the development of adenoviral vectors along with cutting-edge methods for their improvement
* Demonstrates noninvasive imaging of adenovirus-mediated gene transfer
* Discusses utility of adenoviral vectors in animal disease models
* Considers Federal Drug Administration regulations for human clinical trials

Book Description

This book offers a modern treatment of diffusion in solids, covering such core topics as the transport of mass through the lattice of a crystalline solid. Part I of the book develops basic concepts in diffusion field theory and illustrates them with several applications, while Part II focuses on key solid-state principles needed to apply diffusion theory to real materials.

Customer Reviews:

A fine modern book on a good old topic at last !!!.......2005-08-20

To the curious minds of today and tomorrow:

I've recently gotten this book as a present and read a few chapters of it to date. As I am well versed in diffusion, I presume it's ok for me to comment on the book without having fully read it.

After reading a few chapters, and perusing over the entire volume, I was most impressed with Dr. Glickman's text. He's to be commended for having done a very fine job.

Diffusion is inherently a very mathematical subject. Yet, without a proper presentation of the important aspects of the physical phenomena it is barrren and simply reduced to solving partial differential equations. Glickman's book, seems to succeed at providing the physical picture of diffusion with utmost clarity, while maintaining mathematical rigor. Furthermore, it is up to date and exposes the reader to recent developments in the study of diffusion phenomena. The treatment is primarily on the phenomenology of diffusion. If you fancy to learn more about diffusion kinetics, I recommend the book by Khachaturyan (Theory of Structural Phase Transformations in Solids).

As someone who learned diffusion from Physical Metallurgy books, Shewmon's and Carslaw's books, I find Glickman's very refreshing for it's modern, rigorous and comprehensive.

I highly recommend it.

Cheers,

Dr. E.
-----------------------------------

Not a random walk............2003-02-25

...but a coherent and organized text on diffusion.

This is a complete text on the subject of diffusion. Similar to Shewmon's original "Diffusion in Solids", but Glicksman is more complete and modern. Glicksman is worth purchasing even if you already own Shewmon.

Finally, a complete explanation..........2000-04-06

I have found that mathematically intensive books frequently leave out many of the steps that are critical to a complete understanding of the fundamental equations. Diffusion in Solids does a wonderful job of taking you from start to finish in each problem presented. It is a complete tome worth every dollar spent. Thanks Marty!

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Diffusion Phenomena: Cases and Studies
Richard Ghez
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 0306465264

Book Description

This second edition is extensively revised from the author's successful "A Primer of Diffusion Problems" (Wiley, 1988), and includes new exercises, three new appendices, and a new chapter on surface rate limitation and segregation. The goal of Diffusion Phenomena remains the same, which is to teach basic aspects of and methods of solution for diffusion phenomena through physical examples. In this introductory text, the emphasisis placed on modeling and methodology that bridge the gap between physico-chemical statements of certain kinetic processes and their reduction to diffusion problems. This concise and readable, yet authoritative book will appeal to physicists, chemists, biologists, and applied mathematicians studying diffusion regardless of origin of the phenomena or application.

Atomic Diffusion in Disordered Materials: Theory and Applications

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Atomic Diffusion in Disordered Materials: Theory and Applications

Manufacturer: World Scientific Publishing Company
ProductGroup: Book
Binding: Hardcover

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Diffusion in Crystalline Solids (Materials Science and Technology Series)

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Diffusion in Crystalline Solids (Materials Science and Technology Series)
G. E. Murch
Manufacturer: Academic Pr
ProductGroup: Book
Binding: Hardcover

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Dimeta-82 Diffusion in Metals and Alloys (Solid State Phenomena)

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Dimeta-82 Diffusion in Metals and Alloys (Solid State Phenomena)
Dimeta 82
Manufacturer: Trans Tech Publications
ProductGroup: Book
Binding: Hardcover

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Fractal Concepts in Condensed Matter Physics (Springer Series in Solid-State Sciences)

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Fractal Concepts in Condensed Matter Physics (Springer Series in Solid-State Sciences)
T. Nakayama , and K. Yakubo
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover

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ASIN: 3540050442

Book Description

Concisely and clearly written, this book provides a self-contained introduction to the basic concepts of fractals and demonstrates their use in a range of topics in condensed matter physics and statistical mechanics. The first part outlines different fractal structures observed in condensed matter. The main part of the book is dedicated to the dynamical behaviour of fractal structures, including anomalous and percolating systems. The concept of multifractals is illustrated for the metal-insulator quantum phase transition. The authors emphasize the unified description of these different dynamic problems, thus making the book accessible to readers who are new to the field.

Handbook of Gas Diffusion in Solids and Melts (06462G)

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Handbook of Gas Diffusion in Solids and Melts (06462G)
James E. Shelby
Manufacturer: ASM International
ProductGroup: Book
Binding: Hardcover

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Impurities in Semiconductors: Solubility, Migration and Interactions

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Impurities in Semiconductors: Solubility, Migration and Interactions
Victor I. Fistul
Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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Book Description

Although there is a good deal of research concerning semiconductor impurities available, most publications on the subject are very specialized and very theoretical. Until now, the field lacked a text that described the current experimental data, applications, and theory concerning impurities in semiconductor physics. Impurities in Semiconductors: Solubility, Migration and Interactions explores the behavior of impurity atoms in semiconductors, integrating experimental data with theoretical interpretation. It presents the current literature on the state and behavior of impurities in semiconductors. The author explains the basic physics of hydrogen-like impurities to help you understand the properties imparted by these impurities. He also analyzes the macroscopic and microscopic mechanisms of the solubility, and migration of impurities and defects in the crystal lattice. In addition, the book presents a systematic analysis of different effects resulting from the interactions between impurities and other defects in the crystal lattices. This book brings to light work done in the former Soviet Union and highlights several impurities that have potential, but have not yet found widespread application. As such, it will be an invaluable reference for those working in different fields involving the use of electronic materials.

Interfaces and Plasticity (Diffusion and Defect Data)

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Interfaces and Plasticity (Diffusion and Defect Data)

Manufacturer: Scitec Publications
ProductGroup: Book
Binding: Hardcover

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An Introduction to Solid State Diffusion

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An Introduction to Solid State Diffusion
Richard J. Borg , and G. J. Dienes
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

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Book Description

The energetics and mechanisms of diffusion control the kinetics of such diverse phenomena as the fabrication of semiconductors and superconductors, the tempering of steel, geological metamorphism, the precipitation hardening of nonferrous alloys and corrosion of metals and alloys. This work explains the fundamentals of diffusion in the solid state at a level suitable for upper-level undergraduate and beginning graduate students in materials science, metallurgy, mineralogy, and solid state physics and chemistry. A knowledge of physical chemistry such as is generally provided by a one-year undergraduate course is a prerequisite, though no detailed knowledge of solid state physics or crystallography is required.

Customer Reviews:

potent.......2006-12-13

A great book by a not very well known author who spares us the usual fare of passionate women suffering somewhat silently beneath the psycholgoically crushing ennui of bourgeois, male-dominated existence. Instead, we are treated to the tale of a shallow, superficial sentimentalist whose hands drip with the blood of those who fell to the first in a distressingly long line of modern, totalitarian fanaticisms. It reeks of the same kind of naked oppotunism that so many trendy leftist academics exhibit when they too loudly pronounce their oppostion to the mostly imaginary ills of American life - in which one can buy books like this, which repudiates their whole "critique", if I can honor such blather with a word both longer than one syllable and with a pompous French sufffix.

Better History than Novel.......2005-03-11

This novel makes a point of being historically accurate, and for the most part succeeds. Notes at the back of the book help the reader who is unversed in the complexities of the French Revolution understand some details. While the style of writing fits well with the unsatisfactory nature of the Terror, overall the book isn't a great read. The plot is slow to take off, and the characters are difficult to find realistic. However, if what you're looking for is less literary genuis and more history, this is the book for you.
Davies' introduction is somewhat long, providing a lengthy biography of France as well as an introduction to the book. The translation is consistent and I did not encounter any problems that could be blamed on poor translation.

Vital, trenchant, close to the best of French Lit.......2003-01-16

Anatole France's "The Gods Will Have Blood" (1912) is a meditation on the price of unbridled fanaticism. Several key personages and events of the French Revolution figure in the story; most notibly Maximllien Robespierre and the death of Jean-Paul Marat.

But don't expect exquisite characterizations, ala Flaubert, Dostoyevski, Henry James or James Joyce. Such was not France's aim. This is a cautionary tale; one that recapitulates Robespierre, the Terror and Napoleon, and prefigures the Soviets and the Nazis.

In fact, France's articulation of the maddening rationale by fanatical judges--that it is they, not their victims, who suffer as they go about the bloody work of enforcing national policies with the murder of perceived enemies--is visited through concentration camp butcher Rudolph Hoess in William Styron's "Sophie's Choice" (1976).

Only the translation prevents this novel from five stars. Given the fact that French is second only to ancient Greek in terms of damage from translation, and it becomes a minor complaint.

This is a novel by a master (Anatole France won the Nobel for Lit in 1921). Read this book; it's an education.

ponderous and rather dull.......2002-06-01

This is Anatole France's cautionary tale about ideological fanaticism during the "terror" of the French revolution. It is doubly remarkable in that it was published in the decade prior to the Soviet seizure of power, which imposed decades of political terror in Russia as we know, and in that France was a well-known member of the left. Thus, academics rightfully proclaim it as a symbol of the horrors to follow in the 20C.

Unfortunately, I did not enjoy this book very much. Not only is its tone self-important with ponderous and ever-present references to classical mythology - the myth of Orestes as well as the bacchantes - but its innumerable references to obscure figures of the French Revolution, in all their historical accuracy, make it, well, just plain boring. Moreover, the characters appear more like symbols of abstract ideas than flesh-and-blood creatures, and so are both unrealistic psychologically as well as put in situations in which they can carry out long and improbably philosophic discussions.

The plot follows the impoverished members of an apartment building during a time of grave threat to the revolution. There is a fervent young man (a painter and revolutionary fanatic), his missing sister (shacked up with an aristocrat), his simple mother, and an older cynic atheist (an ex-courtier and libertine), who gives refuge to a persecuted priest and innocent peasant girl. As the revolution takes an increasingly murderous turn, they become ever more intimately involved with each other as vehicles to portray historical events.

As such, the book seems to be written for the French high school student, all of whom memorize survey literature from secondary sources to pass rigorous examinations. This makes them able to spout facts as if they had read widely, implying depth and thoughtfulness that all too often isn't there. Of course, France obviously has great depth and his historical research is indeed exhaustive, which taught me a great deal. But the book just didn't make me feel like I was there, which was why I read it. Instead, while reading I felt like I was studying for a high school exam.

As I try to get through the classic authors, I am occasionally surprised at the banality and dullness of some of the most famous works. Perhaps this is because I read them from a rather nave perspective, open and as if they are not revered for whatever, but just as a pure reading experience. Thus, my perceptions are personal and limited to my own experience. While the overwhelming majority of classics are truly wonderful, this one was not.

Recommended only for history buffs and students of French lit.

Perhaps there's a reason this isn't widely read..........2002-03-01

I'll be frank here - I had never even heard of Anatole France before I read "The Gods Will Have Blood." Frankly, though, I don't think I was missing much. That's not to say that the novel is entirely without merit. It offers an amazingly detailed description of the French Revolution and the Reign of Terror, and the dialogue between the antireligious Brotteaux and the kindly Father Longuemare is well written and engrossing.

Nevertheless, "The Gods Will Have Blood" fails in several obvious ways. The characters are static and typecast - Anatole France might as well have hung a sign on Gamelin that reads "EVIL" and be done with it. In fact, the novel is almost completely lacking in subtlety, both in terms of the plot and the characterization as well. Also, the writing style on display here is quite monotonous. The introduction claims that it is "polished perfection", but to me it seems more nondescript and generic than anything else.

Book Description

This digital document is an article from New Criterion, published by Thomson Gale on June 1, 2007. The length of the article is 1629 words. The page length shown above is based on a typical 300-word page. The article is delivered in HTML format and is available in your Amazon.com Digital Locker immediately after purchase. You can view it with any web browser.

Citation Details
Title: Scenes from "The Man of Terror".("The Gods Will Have Blood," Anatole France)(Play)
Author: Glyn Maxwell
Publication: New Criterion (Magazine/Journal)
Date: June 1, 2007
Publisher: Thomson Gale
Volume: 25 Issue: 10 Page: 27(6)

Article Type: Play

Distributed by Thomson Gale

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The Gods Will Have Blood
Anatole/ Davies, Frederick H. France
Manufacturer: Penguin Classics
ProductGroup: Book
Binding: Paperback
ASIN: B000OJ1G1E

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