Phage Display In Biotechnology and Drug Discovery

Book Description

Until recently, the only source for information on the impact of phage display technology on drug discovery research has been laboratory manuals. A thorough reference guide and textbook, Phage Display in Biotechnology and Drug Discovery changes that scenario. It presents the theory and methods behind phage display technology, applications for peptide phage display, protein phage display, and the crucial role of phage display in the development of antibodies. Highlighting the role that phage display has and will continue to play in the discovery and development of protein therapeutics, this book provides a comprehensive overview that will excite anyone interested in recombinant antibodies.

Customer Reviews:

Up to date, in depth and understandable........2006-05-08

This puts everything in one place. This book should be the first reference for anyone interested in phage display. It will save the reader countless hours. I highly recommend.

Book Description

Unifies the complex welter of techniques used for chemical separations by clearly formulating the concepts that are common to them. The mass transport phenomena underlying all separation processes are developed in a simple physical-mathematical form. The limitations and optimum performance of alternative separation techniques and the factors enhancing and limiting separation power can thus be described and explored. Generously illustrated and contains numerous exercises. Long awaited in the scientific community, it breaks new ground in understanding separation processes.

Customer Reviews:

Unified Separation Science Review.......2001-07-31

Is a great book for people starting in any type of separation sciences. It is easy to understand and explains many important concepts that are necessary to understand the chromatographic phenomena.

Very useful and thorough.......1999-04-13

I've used this book in my own research and also in teaching grad level chemical separations course -- an excellent resource. A perfect "career bookend" to Giddings' early work "Dynamics of Chromatography".

Chromatography and Separation Science (SST) (Separation Science and Technology)

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Chromatography and Separation Science (SST) (Separation Science and Technology)
Satinder Ahuja
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

Analytic | Chemistry | Science | Subjects | Books

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ASIN: 0120449811

Book Description

The basic objectives of this book are to: provide basic information on chromatography and separation science; show how simple extraction and partition processes provide the basis for development of chromatography and separation science; describe the role of chromatography and separation science in various fields; discuss the role of chromatography and separation science in development of new methodology; and present new evolving methods and how to select an optimum method.

· The book covers the fundamental physical and chemical phenomena involved in separations
· Provides a concise overview of the basics of transport phenomena and thermodynamics
· Shows the importance of chromatography within separation science

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Validation Review

Handbook of Process Chromatography
Gail K. Sofer , and Lars Hagel
Manufacturer: Academic Press
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

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ASIN: 012654266X

Book Description

This handbook is an excellent reference for graduates and researchers in biotechnology and practitioners in the pharmaceutical industry who wish to develop a commercial chromatographic purification process. The authors guide readers through each step of the development process, beginning with basic chromatography theory and practice and incorporating examples from companies with established processes and approved biotherapeutics. They also cover properties of biological molecules, and reveal pitfalls often encountered in the process. Design strategies are discussed in depth, considering common starting materials and their impact on purification design, scale-up concerns, and validation. The authors use their extensive consulting and teaching experience to present a practical approach to developing an optimal chromatographic process, scaling it up, and meeting requirements set forth by regulatory agencies. The included diskette contains modeling exercises providing valuable insights into the influence of chromatographic parameters on separation results and the impact of process design on production costs, making the Handbook an excellent hands-on teaching tool.

Key Features
* Considers the entire scope of process chromatography, including scale up, regulatory issues, equipment, evaluation studies, scheduling, and cost-effectiveness
* Provides examples from companies with established processes and approved biotherapeutics
* Includes an appendix which lists the most pertinent regulatory documents, allowing the user to gather necessary information to comply with global regulatory expectations for process chromatography
* Contains a modeling program on the included disk

Customer Reviews:

Validation Review.......2002-07-21

Perfect for someone wanting to learn about IQ/OQ/PQ for chromatography. Easy to read. Good presentation. Useful examples. Software is great addition. Very practical approach. Plenty of useful up-to-date references. Great buy!

Plasma Source Mass Spectrometry : Current Trends and Future Developments (Special Publications)

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Plasma Source Mass Spectrometry : Current Trends and Future Developments (Special Publications)
D R Bandura , and J G Holland
Manufacturer: Royal Society of Chemistry
ProductGroup: Book
Binding: Hardcover

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ASIN: 0854046631

Product Description

Atomic spectrometry has exciting new bio-analytical horizons open to it, principally through the developments in the capabilities of ICP-MS coupled with the inventiveness of experimentalists. This is reflected in the use of the technique for ion-, capillary electrophoresis-, liquid- and gas-chromatographic separation in biological applications, as reported in this book. Traditional (environmental, semiconductor, geological and clinical) applications are also well-represented. In addition, recent and future developments in sample introduction devices, multicollector sector, reaction cells and collision cells instruments, as well as co-existence, divergence and potential convergence of atomic and biomolecular mass spectrometries, are discussed. Reflecting the current state of practical ICP-MS and drawing together the latest developments in the field, Plasma Source Mass Spectrometry: Current Trends and Future Developments is ideal for university researchers and laboratory practitioners. It will be of interest to all those involved in the development and application of this technique.

Preparative and Production Scale Chromatography (Chromatographic Science)

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Preparative and Production Scale Chromatography (Chromatographic Science)

Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

Analytic | Chemistry | Science | Subjects | Books

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Book Description

Describes the latest developments in the scaling-up and application of chromatographic operations and demonstrates that production-scale chromatography is a powerful and invaluable separation process. The book covers every important process design and reveals actual, immediately applicable techniques and is designed to appeal to design, chemical/biochemical, and research and development engineers, process development managers, bioprocess technologists, analytical and clinical chemists and biochemists, pharmacists, and upper-level undergraduate, graduate, and continuing-education students in these disciplines.

Affinity Chromatography (Chromatographic Science)

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Affinity Chromatography (Chromatographic Science)
Schott
Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

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Affinity Membranes: Their Chemistry and Performance in Adsorptive Separation Processes

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Affinity Membranes: Their Chemistry and Performance in Adsorptive Separation Processes
Elias Klein
Manufacturer: Wiley-Interscience
ProductGroup: Book
Binding: Paperback

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Nephrology | Internal Medicine | Medicine | Subjects | Books
ASIN: 0471527653

Book Description

Explores the latest findings for both selective and efficient separation devices in the field of kidney research. It is divided into three major sections. Part one deals with the ``biochemistry'' part of the problem, including how to identify ligands of interest, how to link them to synthetic membranes, and some kinetic limitations of frontal elution chromatography. The second part comprehensively discusses the various substrata used in affinity separations and the formation processes of semi-permeable membranes. The final section explores the filtration processes using membranes and the kinetics of separations based on affinity membranes.

Affinity Separations: A Practical Approach (Practical Approach Series)

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Affinity Separations: A Practical Approach (Practical Approach Series)

Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Hardcover

Biochemistry | Biological Sciences | Science | Subjects | Books

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Book Description

Affinity Separations: A Practical Approach is a new collection of affinity-based purification protocols with an international authorship from across the life sciences. The introductory chapter outlines recent advances in ligand-coupling, matrix choice, and operating modes. The second chapter describes methods for obtaining quantitative data from affinity processes. There are specific chapters describing methods for the affinity separation of proteins, nucleic acids, and oligosaccharides. Methods for immunoglobulin purification and immunoaffinity protocols are discussed in a further chapter, and the use of affinity tags in the recovery of engineered proteins in another. Finally, modern techniques for cell separations are outlined. The book presents detailed laboratory protocols together with troubleshooting advice and reviews of recent developments. It is aimed at bench scientists, both those in analytical research laboratories, and those non-specialists looking to apply affinity methods in their work.

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A Century of Separation Science

Manufacturer: CRC
ProductGroup: Book
Binding: Hardcover

Analytic | Chemistry | Science | Subjects | Books

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Book Description

A Century of Separation Science presents an extensive overview of the critical developments in separation science since 1900, covering recent advances in chromatography, electrophoresis, field-flow fractionation, countercurrent chromatography, and supercritical fluid chromatography for high-speed and high-throughput analysis.

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Chiral Chromatography
Thomas E. Beesley , and Raymond P. W. Scott
Manufacturer: Wiley
ProductGroup: Book
Binding: Hardcover

Analytic | Chemistry | Science | Subjects | Books

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Chromatography | Chemistry | Science | Subjects | Books

General | Science | Subjects | Books

Book Description

Chiral Chromatography Thomas E. Beesley Advanced Separation Technologies Inc., Whippany, New Jersey, USA Raymond P. W. Scott Chemistry Department, Georgetown University, Washington DC, USA and Chemistry Department, Birkbeck College, University of London, UK Analytical techniques based on separation processes, such as chromatography and electrophoresis, are finding a growing range of applications in chemical, pharmaceutical and clinical laboratories. The Wiley Separation Science Series provides the analyst in these laboratories with well-focused books covering individual techniques, so that they can be applied more efficiently and effectively to contemporary analytical problems. The different enantiomers of a drug can exhibit widely different physiological activity in degree and nature. As a result, the separation and identification of enantiomers is now a very important analytical problem and chiral chromatography is the natural technique to apply to the resolution of such mixtures. Chiral Chromatography provides the reader with a basic understanding of the nature of chromatographic separations and relates the principles specifically to the separation of enantiomers. The following information is included:
* chiral separations involving both gas and liquid chromatography
* descriptions of the apparatus used for both techniques
* detailed discussion on the retention mechanism that results in chiral selectivity
* the structure and synthesis of a wide range of chirally active stationary phases used in both gas and liquid chromatography
* preparative applications for large scale purification of enantiomers
* applications of capillary electrophoresis and capillary electrochromatography.
In addition to the above, a large number of examples of the separation of both commercially and physiologically interesting chiral mixtures are given, as is a detailed discussion on the mechanism of selectivity of each example. Thomas Beesley was founder and is the CEO for a leading manufacturer of chiral stationary phases and has published papers on TLC, HPLC and chiral separations involving cyclodextrins. He has also coauthored papers with Daniel W. Armstrong, an expert on modern cyclodextrin columns. Raymond Scott has worked in the field of separation science for over 40 years and has contributed extensively to the development of both gas and liquid chromatography publishing over 160 papers on the subjects.

Book Description

Pattern recognition is deemed central to cognition. It appears to follow an optimal algorithm in a wide variety of behaviors and situations. Perceiving Talking Faces proposes an invariant law of pattern recognition to describe how continuously perceived information such as speech input is processed to achieve perception of a category. The book details the author's extensive series of experiments on the use of bimodal cues in speech perception as well as the application of the Fuzzy Logical Model of Perception in speech and a variety of other domains. It presents a blend of theory, mathematical model testing, empirical results, and applications. The author's underlying purpose is to describe and defend a universal principle of psychological theory.

The final part of the book presents the science and applications of the synthetic talking face that was used in most of the speech perception experiments. The CD-ROM that accompanies the book allows the reader to experience the intriguing perceptual phenomena directly; it also provides a valuable research and teaching resource.

Perceiving Talking Faces: From Speech Perception to a Behavioral Principle (Cognitive Psychology)

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Perceiving Talking Faces: From Speech Perception to a Behavioral Principle (Cognitive Psychology)
Dominic W. Massaro
Manufacturer: The MIT Press
ProductGroup: Book
Binding: Paperback
ASIN: B000OQAIPW

Average customer rating:

Too, too scholarly. Not for lay study!

Best Bible EVER

Ultimate Edition for Study

Pass this up

not what I expected

The New Oxford Annotated Bible, New Revised Standard Version with the Apocrypha, Third Edition (Hardcover 9700A)

Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Hardcover

New Revised Standard | Translations | Bibles | Christianity | Religion & Spirituality | Subjects | Books
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The Oxford Bible Commentary

Understanding The Bible

HarperCollins Bible Dictionary

Introduction to the Bible, An (6th Edition)

The New Testament: A Historical Introduction to the Early Christian Writings

ASIN: 019528478X

Book Description

Students, professors and general readers alike have relied upon the Oxford Annotated Bible for essential scholarship and guidance to the world of the Bible for four decades. Now a new editorial board and team of contributors have completely updated this classic work. The result is a volume which maintains and extends the excellence the Annotated's users have come to expect, bringing new insights, information, and approaches to bear upon the understanding of the text of the Bible. The new edition includes a full index to all of the study material (not just to the annotations), and one that is keyed to page numbers, not to citations. And, to make certain points in the text clearer for the reader, there are approximately 40 in-text, line drawing maps and diagrams. With the best of the Annotated's traditional strengths, and the augmentation of new information and new approaches represented in current scholarship, the Third Edition will continue to serve as the reader's and student's constant resource.

Customer Reviews:

Too, too scholarly. Not for lay study!.......2007-09-12

`The New Oxford Annotated Bible' of the New Revised Standard Version (NRSV) translation, with the Apocrypha, was my first, entirely uncritical choice for a study Bible when I began teaching an adult Bible Study class. I have no trouble with the translation, as it is the translation of choice for most American Lutherans, so I accept that.
What I discovered, as I discover with so many other books with the `Oxford' imprimatur, is that while the volume is sound, it is not always the best in the field. When I started looking at other study bibles, I was skeptical of the fancy multicolored sidebars, section headings, and marginalia. Now, I'm not so sure these are such a `bad' thing, even if they don't shout `scholarship'.
The `New Oxford...' certainly shouts scholarship in its copious footnotes to the way in which certain terms have been translated by the NRSV scholars. This was how I discovered that the NRSV is a `politically correct' translation in that it changes all masculine references to terms combining genders (`we' or `men and women' in place of `he' or `man'). This is annoying, as it makes it a less satisfactory translation for scholarship, but, knowing is better than not knowing.
The volume also has superb maps. For these alone the book may be worth owning, as so many other Bible Study maps are inaccurate or lacking in detail. These are combined political and topographical maps for all major periods of Biblical history, such as Canaan in the time of Abraham to Moses, Sinai during the Exodus, Israel in Canaan, and so on. My only complaint is that most maps span two pages, and since the pages are sewn into signatures, scanning or photocopying a good image of the maps is very difficult. Even better is the index to the maps. There are also black and white political maps scattered throughout the text, but these are probably far less useful. It would have been better to gather these all in one place, but that's me. I must say that there is an index to all these maps in the text, so some forgiveness is in order.
From there, things tend to fall off a bit. The volume ends with a series of essays, tables, and a short concordance. This last item seems to me to be quite a waste of space, as it takes up 63 pages, while Strong's Concordance fills over 1800 pages. I suspect Oxford left something out! In fact, my favorite test case, a search for `olive tree', as it appears, for example, in Paul's letter to the Romans, is not to be found. While Oxford has three references to `olive', Strong has 37! The essays I find are sound, but really too short for anything but a quick introduction to their material. Especially noisome is the fact that the essay authors give no bibliography attached to the end of their essays. I did find the table of parallel texts very useful, especially those covering the Old Testament. The parallels of the Synoptic gospels are familiar enough, but the multiple occurrences of, for example, the description of the fall of Jerusalem in Jeremiah and 2 Kings is useful. I did find the chronological table of rulers a useful aide de memoir, although it would have been even more useful to express these genealogically. I seem to recall that Herod the Great, the first of his dynasty, was married to some cousin from the Hasmonean line of rulers. My primary objection to the volume is the dry and uninteresting layout of the scriptures themselves. I get practically no value from the footnoted material, as there is no flag in the text to bring your eyes down to the footnotes. There is also nothing to relieve us of the tedium of verse after verse of small Times New Roman typescript. It uses the method of very subtle verse numbers, to less interfere with the flow of the text, but I'm not so sure I like that, especially when I'm trying to find a verse.
I regret that I can't compare this to another study bible, as I have just started looking at others, thereby having the scales fall from my eyes regarding the value of the Oxford. Stay tuned for more, as I find better guides. I have heard, if you can get your hands on a copy, that the Harper Collins Study Bible, edited by Wayne Meeks, is excellent.

Best Bible EVER.......2007-08-24

This is the best Bible I've ever bought. The NRSV is an excellent, easy to read, yet still scholorly translation of the Bible, and the Oxford Annotated Bible is excellent for the common reader and for the university student. Much less like a "study bible" than the 2nd edition, and much more like something I would analyze the bible with.

Ultimate Edition for Study.......2007-07-29

This book is fantastic and totally informative. From the footnoted annotations filled with historical and interpretive information for all passages, to the linguistic orgin of the translations of each word, this bible is truly a key to grasping a historical version of Christianity.

Also this ecumenical is truly geared for all denominations to learn more about the holistic version of Christianity.

Pass this up.......2007-07-09

Look at other study Bibles like the Concordia Self-Study Bible, before you get this one. It is very limited in notes and is not a study bible at all. I own one and with so many other better choices out there I cannot understand why anyone would bother with this.

not what I expected.......2007-06-13

I was looking forward to using this new Bible for study and for prayer. I was not aware that Apocrypha was not included. No where in the ad was it mentioned that this bible did not include this element of the New Revised Standard Version. I will be able to use this Bible for some of my study program but I had to buy another Bible that included the Apocrypha to assist my prayer life.

The New Oxford Annotated Bible with the Apocrypha, Augmented Third Edition, New Revised Standard Version

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The New Oxford Annotated Bible with the Apocrypha
Poorly Manufactured
the new oxford annotated bible with the apocrypha,augmented third edition, new revised standard version

The New Oxford Annotated Bible with the Apocrypha, Augmented Third Edition, New Revised Standard Version

Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Hardcover

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ASIN: 0195288807

Book Description

Countless students, professors and general readers alike have relied upon The New Oxford Annotated Bible with the Apocrypha for essential scholarship and guidance to the world of the Bible. Now the Augmented Third Edition adds to the established reputation of this premier academic resource. A wealth of new maps, charts, and diagrams further clarify information found in the scripture pages. In addition, section introductions have been expanded and the book introductions have been made more uniform in order to enhance their utility. Of course, the Augmented Third Edition retains the features prized by students, including single column annotations at the foot of the pages, in-text background essays, charts, and maps, a page number-keyed index of all the study materials in the volume, and Oxford's renowned Bible maps. This timely edition maintains and extends the excellence the Annotated's users have come to expect, bringing still more insights, information, and approaches to bear upon the understanding of the biblical text.

Customer Reviews:

The New Oxford Annotated Bible with the Apocrypha.......2007-08-04

This is the best website for ordering books or movies! This book was like new and cost 60.00 dollars less than at the bookstore. Thanks

Poorly Manufactured.......2007-05-20

I had been looking forward to purchasing this edition of the bible The New Oxford Annotated Bible with the Apocrypha, Augmented Third Edition, New Revised Standard Version, Indexed. I researched which translation and edition would meet and, I'm sure, exceed my needs. I was immediately disappointed upon examining the book and almost immediately discovered a manufacturing defect. The edition included tabbed pages. The tabs are attached to the pages with adhesive backing and the paper behind several of the tabs were missing so that the tab stuck to the following page. I tried to gingerly separate the pages with poor results and quickly remembered that I had intended to purchase a quality product and this was not it. Amazon responded quickly to my return request and made the process easy. I would not order this edition again and am still without a bible

the new oxford annotated bible with the apocrypha,augmented third edition, new revised standard version.......2007-04-01

Nice Bible Easy Reading Love the translation

The New Oxford Annotated Bible with the Apocrypha, Augmented Third Edition, College Edition, New Revised Standard Version

Average customer rating:

Not so good study bible
Good Study Bible

The New Oxford Annotated Bible with the Apocrypha, Augmented Third Edition, College Edition, New Revised Standard Version

Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Paperback

General | Christianity | Religion & Spirituality | Subjects | Books

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ASIN: 0195288831

Book Description

Countless students and professors have relied upon The New Oxford Annotated Bible with the Apocrypha for essential scholarship and guidance to the world of the Bible. Now the Augmented Third Edition, College Edition adds to the established reputation of this premier academic resource. A wealth of new maps, charts, and diagrams further clarify information found in the scripture pages. In addition, section introductions have been expanded and the book introductions have been made more uniform in order to enhance their utility. Of course, the Augmented Third Edition retains the features prized by students, including single column annotations at the foot of the pages, in-text background essays, charts, and maps, a page number-keyed index of all the study materials in the volume, and Oxford's renowned Bible maps. This timely edition maintains and extends the excellence the Annotated's users have come to expect, bringing still more insights, information, and approaches to bear upon the understanding of the biblical text.

Customer Reviews:

Not so good study bible.......2007-09-12

Good Study Bible.......2007-05-07

I purchased this bible because I am taking theology classes at Liberty University. This paperback edition is great as it is large enough to read easily but compact enough to carry around. It has the aphocrypha included and lots of references. The study notes are just ok, I would not rely on them too much; they are sketchy at times and are generally from the liberal view of things, BUT they do give some good background info. Overall, this is a good bible for personal or class study, I really like the paperback edition, I previously had the hardcover and it was too bulky

The New Oxford Annotated Bible with the Apocrypha, Augmented Third Edition, New Revised Standard Version, Indexed

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The New Oxford Annotated Bible with the Apocrypha, Augmented Third Edition, New Revised Standard Version, Indexed

Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Leather Bound

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ASIN: 0195288858

Book Description

The New Oxford Annotated Bible with the Apocrypha, Third Edition, New Revised Standard Version

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The New Oxford Annotated Bible with the Apocrypha, Third Edition, New Revised Standard Version
Marc Z. Brettler, Carol A. Newsom, Pheme Perkins Michael D. Coogan
Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Paperback
ASIN: B000OL6MEI

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The New Oxford Annotated Bible with the Apocrypha, Third Edition, New Revised Standard Version
Michael D. Coogan
Manufacturer: Oxford University Press, USA
ProductGroup: Book
Binding: Paperback
ASIN: B000OL7I14

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