Book Description
Dynamic Food Webs challenges us to rethink what factors may determine ecological and evolutionary pathways of food web development. It touches upon the intriguing idea that trophic interactions drive patterns and dynamics at different levels of biological organization: dynamics in species composition, dynamics in population life-history parameters and abundances, and dynamics in individual growth, size and behavior. These dynamics are shown to be strongly interrelated governing food web structure and stability and the role of populations and communities play in ecosystem functioning.
Dyanmic Food Webs not only offers over 100 illustrations, but also contains 8 riveting sections devoted to an understanding of how to manage the effects of environmental change, the protection of biological diversity and the sustainable use of natural resources.
Dyanmic Food Webs is a volume in the Theoretical Ecology series.
* Relates dynamics on different levels of biological organization: individuals, populations, and communities
* Deals with empirical and theoretical approaches
* Discusses the role of community food webs in ecosystem functioning
* Proposes methods to assess the effects of environmental change on the structure of biological communities and ecosystem functioning
* Offers an analyses of the relationship between complexity and stability in food webs
Book Description
Humans have been experimenting with lyophilization, or freeze-drying, as a method to preserve biological structures for over a thousand year. These early efforts focused on food. In recent times, freeze-drying has advanced to the point where it is a common practice for biopharmaceuticals, including blood plasma and vaccines. Lyophilization is still a method of choice for preservation of the growing list of biopharmaceutical products. This comprehensive volume, intended for scientists in both academia and industry, covers a wide range of topics relevant to the formulation of peptide and protein drugs in the freeze-dried state.
Book Description
Thoroughly acquainting the reader with freeze-drying fundamentals-including water properties critical to the process and mechanisms and means of protein stabilization-Freeze-Drying/Lyophilization of Pharmaceutical and Biological Products, Second Edition carves practical guidelines from the very latest theoretical research, technologies, and industrial procedures-ensuring the best execution of steps from closure preparation and regulatory control of products to equipment sterilization and process validation.
Book Description
Finding consistent, analytical discussions of processes and principles of lyophilization can be challenging and often frustrating. The first resource to gather information about the field, Lyophilization: Introduction and Basic Principles is still the book to have on lyophilization. Presenting information in an easy-to-read style, the book comprehensively and authoritatively covers the field. Using plain, unpretentious language, author Thomas A. Jennings pulls together information from diverse sources to provide an authoritative compendium of the lyophilization process and its basic principles. He provides important discussions about the nature of the container-closure system and the equipment, tools, and environments required. Case studies and examples of solutions illustrate the many ways problems can be addressed in the lyophilization process. The book covers: · Properties of lyophilized materials · Product formulation requirements and the thermal properties of formulations · Importance of process water · Phase changes · Thermal analytical methods · Freezing, primary, and secondary drying processes · Effect of vacuum freeze-dryers, both now and in the future Including over 150 illustrations, global symbols, and more than 350 references, this book is the complete guide to lyophilization, its analytical methods, measurement of process parameters, and equipment.
Customer Reviews:
More than introduction. Very useful.......2007-03-31
I have found this book of much aid in my work as a scientist, in fact, some doubts I had were totally dissipated from the clear explanation and practical examples showed here. It is truth that there are some flaws, but it is apparent that they come from Editor, for example Figures showing diagrms etc.
Of great help is the fact that the author gives us access to his abundant collection of data wherefrom one can learn how to handle them. I would wish all the authors make like Dr. Jennings in that sense, for the readers will gain a better comprehension of the phenomena whereby they can obtain the necessary process understanding more easily.
Concerning arrangement of the Chapters, the author used the logic, thus the book was built in such a way that the understanding of one chapter provides the basis for the understanding of the following one.
For all the reasons states, I congratulate Dr. Thomas.A.Jennings and recommend his book.
Disappointing.......2006-06-02
The book is comprehensive and somewhat useful as an introduction into the field. However, it has several flaws that make it fairly disappointing. The text is neither concise nor precise and some information is included that is of questionable value. (60 pages of experimental data in tabular form of thermal properties during cooling and warming of specific solutions are a waste of paper)
Some sections are sloppy. For example on page 64, describing the phase diagram of water, you will find an incomplete sentence, a description that doesn't match the figure (where is the dotted line A-E?), and a very poorly drawn phase diagram (water doesn't really freeze at -15 C at 100 kPa) The author frequently uses non-SI units.
A book in this price range should be properly edited and proof-read, in my opinion. This isn't, so I can't recommend it.
wonderful index included.......1999-06-04
This is THE book on lyophilization (freeze-drying). The exemplary index makes this essential for manufacturers, researchers, academicians, and pharmaceutical companies.
Average customer rating:
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Good Pharmaceutical Freeze-Drying Practice
Manufacturer: Informa Healthcare
ProductGroup: Book
Binding: Hardcover
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ASIN: 1574910310 |
Book Description
This text is devoted to pharmaceutical freeze-drying in all its forms and in all its technological variations. Whether freeze-drying nonsterile tablets or lyophilizing injectables, this book covers all the technological and regulatory requirements. Written by a panel of leading practitioners in the pharmaceutical industry -- production experts, regulatory inspectors, technical consultants, and equipment suppliers -- the information is relevant, usable, and timely. Practical, "how to" chapters serve as training aids, and each section stands on its own as a concise, easy-to-access resource for both managers and technicians.
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Cryopreservation and Freeze-Drying Protocols (Methods in Molecular Biology)
Manufacturer: Humana Press
ProductGroup: Book
Binding: Paperback
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ASIN: 0896032965 |
Book Description
This book provides detailed protocols for all the latest methodologies used to assure the long-term biostorage of a diverse range of biological materials.
Developed in expert laboratories, the protocols have been painstakingly perfected over the years to provide time-tested, step-by-step instructions that ensure robust and reproducible results. Each protocol deals with the preservation of an organelle, cell, or tissue type, and is accessible even to the nonspecialist because of its cookbook approach. Novel protocols can be readily developed with the help of the "hands-on" Notes sections.
Cryopreservation and Freeze-Drying Protocols is an indispensable reference work for both the individual researcher, and all those who want to establish or improve biostorage systems in their laboratories. Its applications range from microbial culture collections, botanic gardens, and zoos to animal husbandry, aquaculture, medicine, human fertilization, and cell and molecular biology.
Book Description
This book describes the technology of freeze-drying with particular emphasis on the properties of the material to be processed, pre-freezing (formulation) and post-drying (stability and shelf life). Materials science principles of glasses, as applied to the study of dried, mainly protein-based biopharmaceuticals and analytical methods are also covered.
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Diffusion Processes During Drying of Solids (Series in Theoretical and Applied Mechanics, Vol 11)
K. N. Shukla
Manufacturer: World Scientific Publishing Company
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ASIN: 9810202784 |
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- a case for restricted tests in clinical trials
|
The Use of Restricted Significance Tests in Clinical Trials (Statistics for Biology and Health)
David S. Salsburg
Manufacturer: Springer
ProductGroup: Book
Binding: Hardcover
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ASIN: 0387977988 |
Book Description
This thought-provoking book discusses the use of statistics in randomized clinical trials. Its aim is two-fold: firstly, it presents a clear account of the design and analysis of experiments in this setting which stresses the foundational issues involved. Secondly, the book seeks to develop the specific tools of analysis which can be derived from Neyman's model of restricted tests. The book is based on the author's many years of experience of clinical trials. Throughout, examples are used from a variety of types of study. As a result, all statisticians and research scientists who work on clinical trials will find this presentation clear and accessible, and very relevant to their own research interests.
Customer Reviews:
a case for restricted tests in clinical trials.......2001-04-07
David Salsburg is a statistician with a good knowledge of the foundations of statistics as well as being a practical statistician with a great deal of clinical trials experience. In Chapter 1 he discusses randomized controlled clinical trials. Chapters 2-5 deal with foundational issues in probability and statistics. It leads to the conclusion that hypothesis testing is appropriate for clinical trials and statistical power against alternatives is an important concept for choosing appropriate test statistics but (1)for most practical problems uniformly most powerful tests do not exist and (2)powerful tests can only be found if one is able to meaningfully restrict the class of alternative hypotheses being considered.
In Chapter 6, Salsburg makes the case for restricted tests by providing a real clinical example. Special methods are then covered in the remaining chapters. Chapter 8 deals with resampling approaches including permutation methods and the bootstrap. In Chapter 10, Neyman's often neglected theory of restricted chi-squared tests, is presented.
This is a well written and unusual book that covers methodology not seen in very many biostatistics books. However, these techniques are very relevant to the clinical trials commonly conducted at pharmaceutical companies. It is an important reference source for biostatisticians.
Those interested in statistical theory and its foundational issues will find clear and concise coverage in the first 5 chapters. However if you want more, take a look at Salsburg's new book "The Lady Tasting Tea" which just came out in 2001. In that book he raises all the same issues and more in the context of discussing the great statisticians of the 20th Century.
Book Description
Three women from different eras—the nineteenth century, mid-twentieth century, and late twentieth century—lead disturbingly parallel lives. All are a bit kinky, all have strange powers they can't explain or control, and all put themselves in harm's way through their attraction to dangerous men. What is their connection to one another? Can they discover who they are in time to save themselves from a nightmarish fate?
Interweaving Celtic myth with a compelling mystery, The Morrigan will draw you into the lives of its memorable characters, inviting you to piece the puzzle together as the story moves toward its explosive climax.
Customer Reviews:
ah the legend and might of Morrigan with a twist!.......2006-12-13
love the reincarnation twist! steamy and a thriller!
Fast paced.......2006-05-20
You will never see where the next turn of the story will take you. A good read!
A Fantastic Story about Woman Power Throughout the Ages!.......2006-03-03
The Morrigan is a special gift for readers looking for books that will turn their minds as their fingers turn the pages. This totally absorbing novel weaves out of time's tapestry three breathtaking stories that invite us to ponder large questions - and to hope that Ms. Maxberry will soon give us more grist for the mill.
A book to give you back your power!.......2006-03-02
I picked up The Morrigan to read on a 2.5 hour road trip......I read all the way there, all the way back and then stayed up that night until I finished it. The author's motto is "A Goddess is a woman that remembers her power" - she couldn't have nailed that any closer to home! I haven't been able to get the premise off of my mind in days - it's made me change the way I think about things, people I know, what I believe and how I act and think. This book will touch the lives of SO many people that are a little bit "tuned in" to their own inner powers!
Can't wait for the movie of The Morrigan!.......2006-02-06
I loved reading The Morrigan! If ever there was a story that was meant to be a movie, this is it! Fast-paced, erotic, and suspenseful, I couldn't put it down. I had fun afterwards thinking about who would play whom in a film version of this excellent story. I'm looking forward the next one by Annette Maxberry.
Books:
- E. coli in Motion (Biological and Medical Physics, Biomedical Engineering)
- Ecology and Natural History of Tropical Bees (Cambridge Tropical Biology Series)
- Encyclopedia of Biodiversity, Five-Volume Set
- Essentials of Anatomy & Physiology plus Applications Manual, Third Edition
- Ethics of the Use of Human Subjects in Research: (Practical Guide)
- Evolutionary Aesthetics
- Extreme Science: Chasing the Ghost Bat: And Other Mysteries of Nature (Extreme Science)
- Five Films by Frederick Wiseman: Titicut Follies, High School, Welfare, High School II, Public Housing
- Free-living Freshwater Protozoa: A Color Guide
- Free-Radical-Induced DNA Damage and Its Repair: A Chemical Perspective
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Aquatic Food Webs: An Ecosystem Approach
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